Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tsutomu Osoda"'
Autor:
Chie Sato, Jiro Shimada, Masaki Yamamoto, Hiroaki Fukunishi, Tsutomu Osoda, Mitsugu Araki, Atsuo Tamura, Kenichiro Tsuda, Shigeyuki Matsumoto, Tomoya Miyakawa, Min Ye, Takashi Kumasaka, Yoko Yoshikawa, Azusa Takeda, Tohru Kataoka, Lizhi Hu, Takeshi Sugimoto, Fumi Shima, Jingling Liao, Shin Muraoka, Yuko Nishiyama, Yuichi Ijiri
Publikováno v:
Proceedings of the National Academy of Sciences. 110:8182-8187
Mutational activation of the Ras oncogene products (H-Ras, K-Ras, and N-Ras) is frequently observed in human cancers, making them promising anticancer drug targets. Nonetheless, no effective strategy has been available for the development of Ras inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb8fcbb9f9253c27414cf3771763c3a
https://doi.org/10.1073/pnas.1217730110
https://doi.org/10.1073/pnas.1217730110
Autor:
Minoru Asogawa, Yukiko Fujiwara, Yoshiko Yamashita, Chiaki Fukushima, Masaaki Asao, Hideshi Shimadzu, Tsutomu Osoda, Ryo Shimizu, Kazuya Nakao
Publikováno v:
ChemInform. 39
Two virtual screening strategies, "query by bagging" (QBag) and "query by bagging with descriptor-sampling" (QBagDS), based on active learning were devised. The QBag strategy generates multiple structure-activity relationship rules by bagging and sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae9828e36fa90327fa7125fe87d322ea
https://doi.org/10.1002/chin.200829218
https://doi.org/10.1002/chin.200829218
Autor:
Tsutomu Osoda, Ryo Shimizu, Masaaki Asao, Minoru Asogawa, Kazuya Nakao, Hideshi Shimadzu, Yoshiko Yamashita, Chiaki Fukushima, Yukiko Fujiwara
Publikováno v:
Journal of chemical information and modeling. 48(4)
Two virtual screening strategies, "query by bagging" (QBag) and "query by bagging with descriptor-sampling" (QBagDS), based on active learning were devised. The QBag strategy generates multiple structure-activity relationship rules by bagging and sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41a8a43ef0892e7750a046eac40ffe8
https://pubmed.ncbi.nlm.nih.gov/18351729
https://pubmed.ncbi.nlm.nih.gov/18351729
Autor:
Morikazu Onji, Tomoya Miyakawa, Toshie Mashiba, Sayo Kataoka, Yoichi Hiasa, Yoko Satta, Keiko Udaka, Tsutomu Osoda, Yasuko Hirachi, Michinori Kohara
Publikováno v:
Immunogenetics. 59(3)
Developing a peptide-based vaccine for the highly variable hepatitis C virus (HCV) remains a challenging task. Variant viruses not only escape antigen presentation but also persist in a patient as quasi-species. Such variants are often antagonistic t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86dd6597e41ef765c69597340ce4e5bf
https://pubmed.ncbi.nlm.nih.gov/17225159
https://pubmed.ncbi.nlm.nih.gov/17225159
Autor:
Yukiko Fujiwara, Yoshiko Yamashita, Tsutomu Osoda, Minoru Asogawa, Chiaki Fukushima, Masaaki Asao, Hideshi Shimadzu, Kazuya Nakao, Ryo Shimizu
Publikováno v:
Journal of Chemical Information & Modeling; Mar2008, Vol. 48 Issue 4, p930-940, 11p
Autor:
Satoru Miyano, Tsutomu Osoda
Publikováno v:
Journal of Cheminformatics
Journal of Cheminformatics, Vol 3, Iss 1, p 50 (2011)
Journal of Cheminformatics, Vol 3, Iss 1, p 50 (2011)
Background Quantitative structure-activity relationships (QSAR) analysis of peptides is helpful for designing various types of drugs such as kinase inhibitor or antigen. Capturing various properties of peptides is essential for analyzing two-dimensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01935ec6c2967efdb68d8b07951dd256