Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Tsutomu Okimura"'
Publikováno v:
Japanese Journal of Pharmacology. 58:314
Autor:
Ikuo Nagata, Tsutomu Okimura
Publikováno v:
Immunopharmacology and Immunotoxicology. 8:327-346
Oral administration of diazepam at doses of 5-10 mg/kg to restraint-stressed mice resulted in almost complete recovery in the stress-induced suppression of the antibody response to sheep red blood cell (SRBC). Moreover, this compound restored the sup
Publikováno v:
Japanese Journal of Pharmacology. 41:237-246
We investigated the correlation between restraint stress-induced alteration of antibody responses and adrenal hormones. Adrenalectomy (Adx) blocked both the suppression of antibody response against T cell-dependent (TD) antigen and the enhancement of
Publikováno v:
Folia Pharmacologica Japonica. 89:1-7
We used lumin (4,4'-(3[2(1-ethyl-4-(1-H)quinolidene) ethylidene]) propenylene [bis(1-ethyl quinolinium iodide)]) as a photosensitive cyanin dye and studied its effects on various allergic reactions. We obtained the following results: Lumin slightly i
Autor:
Hitoshi Ohmori, Kurozumi Seiji, Tsutomu Okimura, Keiji Komoriya, Itaru Yamamoto, Yoshinobu Hashimoto, Tatsuyuki Naruchi, Takeo Ohba
Publikováno v:
Ensho. 1:139-144
TEI-3096は, 他の免疫調節剤同様, 抗炎症作用を有しないが, アジュバント関節炎を10, 50mg/kgの経口投与で有意に抑制した.in vitroでマウス脾臓リンパ球に対するTEI-3096の作用を検討したところ,
Publikováno v:
Folia Pharmacologica Japonica. 89:9-13
Lumin was administered at doses of 0.1 to 100 micrograms/kg for 5 months to NZB/W F1 mice as the model animal for studying systemic lupus erythematosus (SLE), a human autoimmune disease. The increase in anti-thymic autoantibody level was significantl
Publikováno v:
Journal of Immunopharmacology. 4:285-301
TEI-3096 [6-p-chlorobenzyl-5H-2,3,6,7-terahydro-5,7-dioxothiazolo (3,2-a) pyrimidine], a novel thiazolopyrimidine compound has been shown to suppress adjuvant arthritis in rats without any effect on conventional inflammation. We examined the immuno-p
Publikováno v:
Japanese Journal of Pharmacology. 41:239-246
Several experiments were conducted to evaluate the influences of restraint stress on cell-mediated immune events in mice. Delayed type hypersensitivity response to sheep red blood cells was inhibited by the stress, regardless of the timing of restrai
Publikováno v:
Japanese Journal of Pharmacology. 40:513-525
The influences of restraint stress on the functions of T cells, B cells and adherent cells in antibody responses were investigated. Antibody response against sheep red blood cells (SRBC), a T cell-dependent antigen, in cultured splenocytes from restr
Autor:
Tsutomu Okimura
Publikováno v:
Journal of pharmacobio-dynamics. 9(8)
Intraperitoneal administration of neurotropin (NSP) did not modify the antibody response to sheep red blood cells (SRBC) in normal BALB/c mice. However, the suppressed antibody responses to SRBC in restraint-stressed mice were favorably restored to n