Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Tsutomu Hamuro"'
Autor:
Tsutomu Hamuro
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 21:337-342
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84ad58017b051efb7f7ca8360304affa
https://doi.org/10.2491/jjsth.21.337
https://doi.org/10.2491/jjsth.21.337
Autor:
Tsutomu Hamuro, Sadaaki Iwanaga, Hiroshi Kido, Yujiro Asada, Kinta Hatakeyama, Youichi Kunori, Shintaro Kamei, Takashi Kamimura, Yuushi Okumura
Publikováno v:
FEBS Journal. 274:3065-3077
Tissue factor pathway inhibitor (TFPI) is a multivalent Kunitz-type protease inhibitor that primarily inhibits the extrinsic pathway of blood coagulation. It is synthesized by various cells and its expression level increases in inflammatory environme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bb92b8814962a264c5e544e5e720cba
https://doi.org/10.1111/j.1742-4658.2007.05833.x
https://doi.org/10.1111/j.1742-4658.2007.05833.x
Autor:
Shuichi Horie, Hiroyuki Itabe, Tsutomu Hamuro, Naoki Ohkura, Sayuri Hiraishi, Tatsuya Takano, Juzo Matsuda, Yuichi Kamikubo
Publikováno v:
Antioxidants & Redox Signaling. 6:705-712
Tissue factor pathway inhibitor (TFPI) is a Kunitz-type protease inhibitor that inhibits the initial reactions of blood coagulation. In this study, we explored the nature of active components that reduce the anticoagulant activity of TFPI in oxidized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17c247324f2e92f631eab1415a67d185
https://doi.org/10.1089/1523086041361686
https://doi.org/10.1089/1523086041361686
Autor:
Yoichi Nakamura, Tsutomu Hamuro, Hiromi Matsubara, Kazufumi Nakamura, Keiko Ohta, Kengo Fukushima-Kusano, Tohru Ohe, Chikao Yutani
Publikováno v:
Thrombosis Research. 111:137-142
Introduction : Tissue factor plays a key role in the extrinsic coagulation pathway and is induced by inflammatory cytokines. Atrial myocarditis has been detected recently in some patients with lone atrial fibrillation. Virchow's triad of low blood fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd24976e2dfd2e080785c4d841ddb0b7
https://doi.org/10.1016/s0049-3848(03)00405-5
https://doi.org/10.1016/s0049-3848(03)00405-5
Autor:
Tsutomu HAMURO
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 13:80-84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faf2d567f293f5afd371dc0289a4a0a1
https://doi.org/10.2491/jjsth.13.80
https://doi.org/10.2491/jjsth.13.80
Publikováno v:
Thrombosis and Haemostasis. 86:1547-1554
SummaryWe investigated the localisation, gene expression, and activity of tissue factor pathway inhibitor (TFPI) in endothelial cells (EC) grown in static conditions or under shear stress, in the presence of unfractionated heparin (UFH) and two low-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99bd8a6f6a53d5ae5e3975545cdc7bb
https://doi.org/10.1055/s-0037-1616761
https://doi.org/10.1055/s-0037-1616761
Autor:
Tomohiro Nakagaki, Seiji Miyamoto, Tsutomu Hamuro, Akinobu Funatsu, Hisao Kato, Yu-ichi Kamikubo, Sumiyo Takemoto, Yo Nakahara, Shintaro Kamei
Publikováno v:
Thrombosis Research. 89:179-186
We have recently shown that a complex formation of tissue factor pathway inhibitor (TFPI) and factor Xa (Xa) promotes a clearance of proteoglycans-associated TFPI. In the current studies, the interaction between human recombinant TFPI (h-rTFPI) and X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ee65c30a74b563bfbf6774c78cf555
https://doi.org/10.1016/s0049-3848(98)00003-6
https://doi.org/10.1016/s0049-3848(98)00003-6
Publikováno v:
FEBS Letters. 421:197-202
Tissue factor pathway inhibitor (TFPI) is mainly synthesized in vascular endothelial cells and exhibits a strong and specific inhibitory activity against tissue factor-mediated blood coagulation. In the present study, we demonstrate that human recomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99581cb942a4263df38da980e0f9732
https://doi.org/10.1016/s0014-5793(97)01559-7
https://doi.org/10.1016/s0014-5793(97)01559-7
Autor:
Seiji Miyamoto, Akinobu Funatsu, Tsutomu Hamuro, Sumiyo Takemoto, Yo Nakahara, Yu-ichi Kamikubo
Publikováno v:
FEBS Letters. 407:116-120
Tissue-factor pathway inhibitor (TFPI) inhibits the procoagulant activity of the tissue-factor/factor VIIa complex. It was recently reported that TFPI prevented restenosis following tissue injury in a rabbit atherosclerotic model. In order to clarify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05904ada9895c1ddc9af259136ccf18
https://doi.org/10.1016/s0014-5793(97)00312-8
https://doi.org/10.1016/s0014-5793(97)00312-8
Autor:
Seiji Miyamoto, Hisao Kato, Jun-ichi Matsuda, Tsutomu Hamuro, Akinobu Funatsu, Kaoru Jyu-ri, Yu-ichi Kamikubo, Shintaro Kamei
Publikováno v:
Thrombosis Research. 83:161-173
The very rapid clearance of human recombinant tissue factor pathway inhibitor (h-rTFPI) may result from its binding to vascular proteogly can and LDL receptor-related protein (LRP). To investigate the effect of factor Xa on the clearance of h-rTFPI,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76160e50d8bb659725c09c26c3c57036
https://doi.org/10.1016/0049-3848(96)00117-x
https://doi.org/10.1016/0049-3848(96)00117-x