Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Tsutomu, Kawata"'
Autor:
Motoji Kogushi, Kenichi Chiba, Takashi Musha, Shuichi Suzuki, Akiharu Kajiwara, Ieharu Hishinuma, Tetsuya Kawahara, Tsutomu Kawata, Toshiyuki Matsuoka, Kimiyo Murakami, Akifumi Kimura, Hiroko Kuramochi
Publikováno v:
European Journal of Pharmacology. 666:158-164
Thrombin is a powerful agonist for a variety of cellular responses including platelet aggregation and vascular smooth muscle cell (SMC) proliferation. These actions are mediated by a thrombin receptor known as protease-activated receptor-1 (PAR-1). R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298dd42cf3f3923e39da5826e9872958
https://doi.org/10.1016/j.ejphar.2011.05.034
https://doi.org/10.1016/j.ejphar.2011.05.034
Publikováno v:
Journal of Endotoxin Research. 10:185-194
E5564, a lipid A analogue, is a potent antagonist of lipopolysaccharide (LPS). Clinically, E5564 was developed as a possible therapy for treatment of sepsis and septic shock. Surface plasmon resonance (SPR) analysis indicates that E5564 binds to LPS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702385f385c182aab464c03f12f58faf
https://doi.org/10.1177/09680519040100030501
https://doi.org/10.1177/09680519040100030501
Autor:
Shoutaro Tsuji, Shizuo Akira, Takashi Akazawa, Kumao Toyoshima, Tsutomu Kawata, Osamu Takeuchi, Junji Uehori, Misako Matsumoto, Tsukasa Seya, Ichiro Azuma
Publikováno v:
Infection and Immunity. 71:4238-4249
The Mycobacterium bovis bacillus Calmette-Guérin (BCG) cell wall skeleton (CWS) consists of mycolic acids, arabinogalactan, and peptidoglycan (PGN) and activates Toll-like receptor 2 (TLR2) and TLR4. Here we investigated the ability of the essentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7c73c6df769894eadcaefb4e14a4a42
https://doi.org/10.1128/iai.71.8.4238-4249.2003
https://doi.org/10.1128/iai.71.8.4238-4249.2003
Autor:
Manabu Murakami, Seiji Yoshikawa, Tsutomu Kawata, Tatsuo Horizoe, Hiroe Minami, Yorihisa Hoshino, Shinya Abe, Hitoshi Harada, Junsaku Nagaoka, Nobuyuki Yasuda, Isao Tanaka, Osamu Asano, Takashi Inoue, Seiichi Kobayashi, Kaya Nagata
Publikováno v:
European Journal of Pharmacology. 459:159-166
The adenosine receptor subtype mediating glucose production by glycogenolysis and gluconeogenesis was studied in primary cultured rat hepatocytes. Adenosine and adenosine agonists caused cyclic AMP accumulation in rat hepatocytes. The order of potenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c263362bdd6124061c366caffb8799e
https://doi.org/10.1016/s0014-2999(02)02832-7
https://doi.org/10.1016/s0014-2999(02)02832-7
Autor:
Daniel P. Rossignol, Maureen A. Mullarkey, J R Bristol, Tsutomu Kawata, Fabian Gusovsky, Melinda Przetak, Akufumi Kimura, William J. Christ, Jesse Chow, Jeffrey Rose, Seiichi Kobayashi
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 304:1093-1102
Alpha-D-glucopyranose,3-O-decyl-2-deoxy-6-O-[2-deoxy-3-O-[(3R)-3-methoxydecyl]-6-O-methyl-2-[[(11Z)-1-oxo-11-octadecenyl]amino]-4-O-phosphono-beta-D-glucopyranosyl]-2-[(1,3-dioxotetradecyl)amino]-1-(dihydrogen phosphate), tetrasodium salt (E5564) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3e6c351af996936ca8c0e87b66746d
https://doi.org/10.1124/jpet.102.044487
https://doi.org/10.1124/jpet.102.044487
Publikováno v:
Journal of Japan Institute of Electronics Packaging. 5:166-170
Bumpless ILB (Inner Lead Bonding) technology is characterized by the use of ultrasonic bonding method to bond gold plated inner leads directly to the aluminum electrodes of semiconductor device without forming metallic bumps on the electrodes. This p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33775239a13d0fb92d0bfb02a9f359cb
https://doi.org/10.5104/jiep.5.166
https://doi.org/10.5104/jiep.5.166
Autor:
Shinya Abe, Junsaku Nagaoka, Takashi Inoue, Osamu Asano, Kaya Nagata, Manabu Murakami, Hitoshi Harada, Nobuyuki Yasuda, Seiichi Kobayashi, Isao Tanaka, Tatsuo Horizoe, Tsutomu Kawata
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:2709-2726
A series of 2-alkynyl-8-aryladenine derivatives bearing an amide moiety at the 9-position of adenine was synthesized. These analogues were evaluated for inhibitory activity on N-ethylcarboxamidoadenosine (NECA)-induced glucose production in primary c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20dd288283ff82ab759f40afe7693646
https://doi.org/10.1016/s0968-0896(01)00201-2
https://doi.org/10.1016/s0968-0896(01)00201-2
Publikováno v:
The Astrophysical Journal. 550:1075-1092
Recent high-resolution observations from photospheric magnetograms made with the SOHO/Michelson Doppler Imager instrument and the Swedish Vacuum Solar Telescope on La Palma showed that magnetic flux tubes in the quiet photospheric network of the sola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff954ce3a4bed34a91171c80e71dab00
https://doi.org/10.1086/319802
https://doi.org/10.1086/319802
Publikováno v:
The Astrophysical Journal. 537:1063-1072
To explain the observed dynamics of the small-scale magnetic flux tubes in the quiet photospheric network, Furusawa & Sakai presented simulation results on the collision of two flux tubes. They found that shock waves appear during the collision of tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac451bb7d8b889cd21e6f37436c31e55
https://doi.org/10.1086/309064
https://doi.org/10.1086/309064