Fractional retention of technetium-99m-sestamibi as an index of P-glycoprotein expression in untreated breast cancer patients

Autor: Silvana DEL VECCHIO, Ciarmiello, A., Pace, L., Potena, M. I., Carriero, M. V., Mainolfi, C., Thomas, R., D Aiuto, G., Tsuruo, T., Salvatore, M.

Publikováno v: ResearcherID
Scopus-Elsevier

The multidrug-resistant phenotype is characterized by the reduced intracellular retention of several structurally and functionally unrelated cytotoxic compounds due to the energy-dependent pump activity of P-glycoprotein (Pgp). Because 99mTc-sestamib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::105b34f03f516310bad372167ba8d2bb
http://hdl.handle.net/11588/155229

Reversal of adriamycin resistance by recombinant alpha-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells

Autor: Scala S, Roberto Pacelli, Rv, Iaffaioli, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Ar, Bianco

Publikováno v: Europe PubMed Central

Reversal of the drug resistance phenotype by the use of agents which induce cell differentiation offers an experimental approach to the study of chemoresistance. In numerous in vitro models, alpha-interferon (alpha-IFN) has been shown to induce pheno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f59b81aa44f97900eb152d058ec5c41d
http://hdl.handle.net/11386/3104407

Isolation of murine and human homologues of the fission-yeast dis3+ gene encoding a mitotic-control protein and its overexpression in cancer cells with progressive phenotype

Autor: Lim J, Kuroki T, Kouichi Ozaki, Kohsaki H, Yamori T, Tsuruo T, Nakamori S, Imaoka S, Endo M, Nakamura Y

Publikováno v: Europe PubMed Central

To investigate genes involved in metastasis, we used a differential display method to compare the levels of gene expression in three cell lines derived from murine colon-adenocarcinoma 26 that show different metastatic potentials. The results, and su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f02698882787b3dbc407f2784cf4c7b9
https://pubmed.ncbi.nlm.nih.gov/9041195

Immunohistochemical detection of the multidrug transport protein P170 in human normal tissues and malignant lymphomas

Autor: Pileri, Sa, Sabattini, E, Falini, B, Tazzari, Pl, Gherlinzoni, F, Michieli, Mg, Damiani, D, Zucchini, L, Gobbi, Marco, Tsuruo, T.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3710::77f56d1b47e1ad9151dec84b38df4e36
http://hdl.handle.net/11567/380531

Distribution of multidrug resistance-associated P-glycoprotein in normal and neoplastic human tissue

Autor: van der Valk, P., van Kalken, C.K., Ketelaars, H., Broxterman, H.J., Scheffer, G., Kuijper, C.M., Tsuruo, T., Lankelma, J., Meijer, C.J.L.M., Pinedo, H.M.

Publikováno v: Annals of Oncology, 1, 56-64. Oxford University Press
van der Valk, P, van Kalken, C K, Ketelaars, H, Broxterman, H J, Scheffer, G, Kuijper, C M, Tsuruo, T, Lankelma, J, Meijer, C J L M & Pinedo, H M 1990, ' Distribution of multidrug resistance-associated P-glycoprotein in normal and neoplastic human tissue ', Annals of Oncology, vol. 1, pp. 56-64 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1abe55ff34b5393d933b80c9c381e163
https://research.vumc.nl/en/publications/1d201d99-850f-48ff-8fd1-ce0ff8dcc8a4