Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Tsung-Ying Shen"'
Autor:
Tsung-ying Shen, 沈宗穎
102
Affected by the Cultural Revolution in the past, China had stagnation of economic development and a serious decline in the standard of living. In order to break the closed economic system, Deng Xiaoping boldly brought up &;quot;The reform an
Affected by the Cultural Revolution in the past, China had stagnation of economic development and a serious decline in the standard of living. In order to break the closed economic system, Deng Xiaoping boldly brought up &;quot;The reform an
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/8x2788
Autor:
Tsung-Ying Shen, C.G. Yeh, X. Cai, Scannell Rt, S.-B. Hwang, J.B. Eckman, Hussoin Ms, Killian Db, Yaeger D, Changgeng Qian, Libertine-Garahan L, Ip Sh
Publikováno v:
Journal of Medicinal Chemistry. 41:1970-1979
By incorporating an N-hydroxyurea functionality onto diaryltetrahydrofurans, a novel series of compounds was investigated as dual 5-lipoxygenese (5-LO) inhibitor and platelet-activating factor (PAF) receptor antagonist. These dual functional compound
Publikováno v:
Biochemical and Biophysical Research Communications. 244:873-876
Glycosyl phosphatidylinositol phospholipase C (GPI-PLC) ofTrypanosoma bruceiis inhibited bymyo-inositol(Ins)-1-O-dodecylphosphonate (VP-602L). Several novel fluoro-substituted analogs of 2-deoxy-myo-Ins-1-O-dodecylphosphonate, among which 2-deoxy-2-f
Publikováno v:
Journal of Biological Chemistry. 271:15468-15477
Phosphatidylinositol-specific phospholipase C (PI-PLC) from Bacillus cereus is inhibited by myo-inositol-1-O-dodecylphosphonate (Ins-1-O-dodecylphosphonate) (Morris, J. C., Ping-Sheng, L., Shen, T. Y., and Mensa-Wilmot, K. (1995) J. Biol. Chem. 270,
Publikováno v:
Tetrahedron Letters. 36:7403-7406
Three 2-deoxy-2-fluorinated inositols and their 1-0-dodecylphosphonate derivatives have been synthesized as non-cleavable inhibitors of glycosyl phosphatidylinositol phospholipase C. Their structure-activity relationship is discussed.
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:1637-1642
Futoenone and a series of its derivatives have shown inhibitory activities against matrix metalloproteinases. The molecular modelings of these compounds indicate the preferred binding of the P2′ site of the enzymes.
Autor:
Tsung-Ying Shen
Publikováno v:
Journal of the Chinese Chemical Society. 42:617-621
Following the discovery of salicylates and its conversion to aspirin, natural products research has provided many promising leads for further modification as anti-inflammatory and analgesic agents. Recent studies have focused on biosynthesis inhibito
Publikováno v:
Journal of Biological Chemistry. 270:2517-2524
Glycosylphosphatidylinositol phospholipase C (GPI-PLC) from Trypanosoma brucei and phosphatidylinositol phospholipase C (PI-PLC) from Bacillus sp. both cleave glycosylphosphatidylinositols (GPIs). However, phosphatidylinositol, which is efficiently c
Autor:
Hailun Tang, Mark Brown, Yuesheng Wang, Xiaohui Chen, Yihua Zhang, Yunpeng Ye, Guofeng Huang, Tsung Ying Shen, Martin Tenniswood, Hai-Xiao Zhai
Publikováno v:
Biochemical and biophysical research communications. 307(1)
To identify inhibitors of the intrinsic N-acetylated alpha-linked acidic dipeptidase (NAALADase) activity of prostate specific membrane antigen (PSMA) that may be useful for targeting imaging agents or chemotherapeutic drugs to disseminated prostate
Publikováno v:
Ullmann's Encyclopedia of Industrial Chemistry
The article contains sections titled: 1. Introduction 2. Glucocorticoids 3. Nonsteroidal Anti-inflammatory Drugs and Selective COX-2 Inhibitors 3.1. Salicylates 3.2. ArylaceticAcids 3.3. Arylacetic Acid Prodrugs 3.4. Arylpropionic Acids 3.5. Acidic E