Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Tsung-I. Hsu"'
Autor:
Yu-Ting Tsai, Wei-Lun Lo, Pin-Yuan Chen, Chiung-Yuan Ko, Jian-Ying Chuang, Tzu-Jen Kao, Wen-Bing Yang, Kwang-Yu Chang, Chia-Yang Hung, Ushio Kikkawa, Wen-Chang Chang, Tsung-I. Hsu
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-17 (2022)
Abstract Background Sp1 is involved in the recurrence of glioblastoma (GBM) due to the acquirement of resistance to temozolomide (TMZ). Particularly, the role of Sp1 in metabolic reprogramming for drug resistance remains unknown. Methods RNA-Seq and
Externí odkaz:
https://doaj.org/article/41e5eb2931d64c3ea1398dfe091319be
Autor:
Tzu-Chi Chen, Jian-Ying Chuang, Chiung-Yuan Ko, Tzu-Jen Kao, Pei-Yu Yang, Chun-Hui Yu, Ming-Sheng Liu, Siou-Lian Hu, Yu-Ting Tsai, Hardy Chan, Wen-Chang Chang, Tsung-I. Hsu
Publikováno v:
Redox Biology, Vol 30, Iss , Pp - (2020)
Drug resistance is the main obstacle in the improvement of chemotherapeutic efficacy in glioblastoma. Previously, we showed that dehydroepiandrosterone (DHEA), one kind of androgen/neurosteroid, potentiates glioblastoma to acquire resistance through
Externí odkaz:
https://doaj.org/article/6055e2a7341b4dfda7f02b0e7adbc303
Autor:
Kwang-Yu Chang, Tsung-I. Hsu, Che-Chia Hsu, Shan-Yin Tsai, Jr-Jiun Liu, Shao-Wen Chou, Ming-Sheng Liu, Jing-Ping Liou, Chiung-Yuan Ko, Kai-Yun Chen, Jan-Jong Hung, Wen-Chang Chang, Cheng-Keng Chuang, Tzu-Jen Kao, Jian-Ying Chuang
Publikováno v:
Redox Biology, Vol 13, Iss C, Pp 655-664 (2017)
Acquisition of temozolomide (TMZ) resistance is a major factor leading to the failure of glioblastoma (GBM) treatment. The exact mechanism by which GBM evades TMZ toxicity is not always related to the expression of the DNA repair enzyme O6-methylguan
Externí odkaz:
https://doaj.org/article/2cfb7d3e1f924bd3bbb0af1a34f9768a
Autor:
Hsien-Chung Chen, Hong-Yi Lin, Yung-Hsiao Chiang, Wen-Bin Yang, Chung-Han Wang, Pei-Yu Yang, Siou-Lian Hu, Tsung-I Hsu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Introduction Glioblastoma (GBM) poses a significant challenge in oncology, with median survival times barely extending beyond a year due to resistance to standard therapies like temozolomide (TMZ). This study introduces a novel therapeutic s
Externí odkaz:
https://doaj.org/article/9305cadfe47840a985dd820ce646bf31
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 751-760 (2023)
Mild traumatic brain injury (mTBI) is a prevalent health concern with variable recovery trajectories, necessitating reliable prognostic markers. Insulin-like growth factor 1 (IGF-1) emerges as a potential candidate because of its role in cellular gro
Externí odkaz:
https://doaj.org/article/e7e606410f6548c4a80884b44d05631f
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Glioblastoma (GBM) is a highly aggressive and lethal brain tumor with limited treatment options, such as the chemotherapeutic agent, temozolomide (TMZ). However, many GBM tumors develop resistance to TMZ, which is a major obstacle to effecti
Externí odkaz:
https://doaj.org/article/ba2167d4f6014e08979784f9b1de8631
Autor:
Tsung-I Hsu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/18f8dfae522b4ca2ab2f0eb57022bbce
Publikováno v:
Life, Vol 14, Iss 1, p 139 (2024)
A 50-year-old male presented to the emergency room after experiencing sudden right upper limb facial numbness and dysphasia, followed by full recovery. A brain CT scan showed hyperdense lesions within the left hemispheric sulcus, which raised suspici
Externí odkaz:
https://doaj.org/article/e71499f7569e4c4ca763609d789811c0
Autor:
An-Chih Wu, Wen-Bin Yang, Kwang-Yu Chang, Jung-Shun Lee, Jing-Ping Liou, Ruei-Yuan Su, Siao Muk Cheng, Daw-Yang Hwang, Ushio Kikkawa, Tsung-I Hsu, Chih-Yang Wang, Wen-Chang Chang, Pin-Yuan Chen, Jian-Ying Chuang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Glioblastoma (GBM) is the most aggressive and lethal brain tumor. Although the histone deacetylase (HDAC)/transcription factor axis promotes growth in GBM, whether HDACs including HDAC6 are involved in modulating long non-coding R
Externí odkaz:
https://doaj.org/article/d9672530025d48d3b6d942240400f4bd
Autor:
Wen-Bin Yang, An-Chih Wu, Tsung-I Hsu, Jing-Ping Liou, Wei-Lun Lo, Kwang-Yu Chang, Pin-Yuan Chen, Ushio Kikkawa, Shung-Tai Yang, Tzu-Jen Kao, Ruei-Ming Chen, Wen-Chang Chang, Chiung-Yuan Ko, Jian-Ying Chuang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Abstract DNA repair promotes the progression and recurrence of glioblastoma (GBM). However, there remain no effective therapies for targeting the DNA damage response and repair (DDR) pathway in the clinical setting. Thus, we aimed to conduct a compre
Externí odkaz:
https://doaj.org/article/0550dd11627c4cb1b510f29cabb3b452