Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Tsung-I Hsu"'
Autor:
Hsien-Chung Chen, Hong-Yi Lin, Yung-Hsiao Chiang, Wen-Bin Yang, Chung-Han Wang, Pei-Yu Yang, Siou-Lian Hu, Tsung-I Hsu
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-17 (2024)
Abstract Introduction Glioblastoma (GBM) poses a significant challenge in oncology, with median survival times barely extending beyond a year due to resistance to standard therapies like temozolomide (TMZ). This study introduces a novel therapeutic s
Externí odkaz:
https://doaj.org/article/9305cadfe47840a985dd820ce646bf31
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 751-760 (2023)
Mild traumatic brain injury (mTBI) is a prevalent health concern with variable recovery trajectories, necessitating reliable prognostic markers. Insulin-like growth factor 1 (IGF-1) emerges as a potential candidate because of its role in cellular gro
Externí odkaz:
https://doaj.org/article/e7e606410f6548c4a80884b44d05631f
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Glioblastoma (GBM) is a highly aggressive and lethal brain tumor with limited treatment options, such as the chemotherapeutic agent, temozolomide (TMZ). However, many GBM tumors develop resistance to TMZ, which is a major obstacle to effecti
Externí odkaz:
https://doaj.org/article/ba2167d4f6014e08979784f9b1de8631
Autor:
Tsung-I Hsu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/18f8dfae522b4ca2ab2f0eb57022bbce
Publikováno v:
Life, Vol 14, Iss 1, p 139 (2024)
A 50-year-old male presented to the emergency room after experiencing sudden right upper limb facial numbness and dysphasia, followed by full recovery. A brain CT scan showed hyperdense lesions within the left hemispheric sulcus, which raised suspici
Externí odkaz:
https://doaj.org/article/e71499f7569e4c4ca763609d789811c0
Autor:
An-Chih Wu, Wen-Bin Yang, Kwang-Yu Chang, Jung-Shun Lee, Jing-Ping Liou, Ruei-Yuan Su, Siao Muk Cheng, Daw-Yang Hwang, Ushio Kikkawa, Tsung-I Hsu, Chih-Yang Wang, Wen-Chang Chang, Pin-Yuan Chen, Jian-Ying Chuang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-19 (2022)
Abstract Background Glioblastoma (GBM) is the most aggressive and lethal brain tumor. Although the histone deacetylase (HDAC)/transcription factor axis promotes growth in GBM, whether HDACs including HDAC6 are involved in modulating long non-coding R
Externí odkaz:
https://doaj.org/article/d9672530025d48d3b6d942240400f4bd
Autor:
Wen-Bin Yang, An-Chih Wu, Tsung-I Hsu, Jing-Ping Liou, Wei-Lun Lo, Kwang-Yu Chang, Pin-Yuan Chen, Ushio Kikkawa, Shung-Tai Yang, Tzu-Jen Kao, Ruei-Ming Chen, Wen-Chang Chang, Chiung-Yuan Ko, Jian-Ying Chuang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 10, Pp 1-13 (2021)
Abstract DNA repair promotes the progression and recurrence of glioblastoma (GBM). However, there remain no effective therapies for targeting the DNA damage response and repair (DDR) pathway in the clinical setting. Thus, we aimed to conduct a compre
Externí odkaz:
https://doaj.org/article/0550dd11627c4cb1b510f29cabb3b452
Autor:
Chie-Hong Wang, Hsuan-Cheng Wu, Chen-Wei Hsu, Yun-Wei Chang, Chiung-Yuan Ko, Tsung-I Hsu, Jian-Ying Chuang, Tsui-Hwa Tseng, Shao-Ming Wang
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14727 (2022)
Myeloid zinc finger 1 (MZF1), also known as zinc finger protein 42, is a zinc finger transcription factor, belonging to the Krüppel-like family that has been implicated in several types of malignancies, including glioblastoma multiforme (GBM). MZF1
Externí odkaz:
https://doaj.org/article/994897ef970a4b32af532cf84701327b
Autor:
Chia-Hung Chien, Jian-Ying Chuang, Shun-Tai Yang, Wen-Bin Yang, Pin-Yuan Chen, Tsung-I Hsu, Chih-Yuan Huang, Wei-Lun Lo, Ka-Yen Yang, Ming-Sheng Liu, Jui-Mei Chu, Pei-Hsuan Chung, Jr-Jiun Liu, Shao-Wen Chou, Shang-Hung Chen, Kwang-Yu Chang
Publikováno v:
Journal of Biomedical Science, Vol 26, Iss 1, Pp 1-16 (2019)
Abstract Background Intratumor subsets with tumor-initiating features in glioblastoma are likely to survive treatment. Our goal is to identify the key factor in the process by which cells develop temozolomide (TMZ) resistance. Methods Resistant cell
Externí odkaz:
https://doaj.org/article/a4d420e0b4e94a6d81430e61fa42269e
Autor:
Shao-Ming Wang, Hong-Yi Lin, Yen-Lin Chen, Tsung-I Hsu, Jian-Ying Chuang, Tzu-Jen Kao, Chiung-Yuan Ko
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-12 (2019)
Abstract Background The small population of glioma stem-like cells (GSCs) contributes to tumor initiation, malignancy, and recurrence in glioblastoma. However, the maintenance of GSC properties in the tumor microenvironment remains unclear. In glioma
Externí odkaz:
https://doaj.org/article/a18f117ea2824020ad47a4e7e861366d