Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Tsung-Chih Hsieh"'
Autor:
Tsung-chih Hsieh, 謝宗智
97
JLT (Jarrow-Lando-Turnbull) model provides us an important and practical method to value some financial instrument such like the defaultable zero-coupon bonds or other credit derivatives such as credit spread options. But under the JLT model
JLT (Jarrow-Lando-Turnbull) model provides us an important and practical method to value some financial instrument such like the defaultable zero-coupon bonds or other credit derivatives such as credit spread options. But under the JLT model
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/50485884668058854482
Autor:
Tsung-Chih Hsieh, 謝宗志
95
Taiwanofungus camphoratus, a medical mushroom known only from Taiwan as ‘niu-chang chih’ or ‘jang-jy’. It is rare and expensive because it grows only on the inner heartwood wall of the endemic evergreen Cinnamonum kanehirai and is not
Taiwanofungus camphoratus, a medical mushroom known only from Taiwan as ‘niu-chang chih’ or ‘jang-jy’. It is rare and expensive because it grows only on the inner heartwood wall of the endemic evergreen Cinnamonum kanehirai and is not
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/2q7ceq
Autor:
Tsung-chih Hsieh, 謝宗志
94
Polylactic acid (PLA) and chitosan are biodegradable materials, and they can be absorbed in the human body and had excellent biocompatibility; chitosan can promote wound healing and inhibit bacteria''s further growth. PLA surgical suture comp
Polylactic acid (PLA) and chitosan are biodegradable materials, and they can be absorbed in the human body and had excellent biocompatibility; chitosan can promote wound healing and inhibit bacteria''s further growth. PLA surgical suture comp
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/48302410234779629429
Autor:
Ya-Hui Chi, Chun-Ping Chang, Teng-Kuang Yeh, Wan-Ping Wang, Yen-Ting Chen, Chia-Hua Tsai, Yan-Fu Chen, Yi-Yu Ke, Jing-Ya Wang, Ching-Ping Chen, Tsung-Chih Hsieh, Mine-Hsine Wu, Chiung-Tong Chen
Publikováno v:
Cancer Research. 83:523-523
Upregulation of Aurora kinases has been associated with increased tumor progression, and thus they are appealing targets for the development of anti-cancer therapies. In addition to have a critical role in cell cycle regulation, Aurora kinases have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d402a7430ac3bca0e58167978984b285
https://doi.org/10.1158/1538-7445.am2023-523
https://doi.org/10.1158/1538-7445.am2023-523
Publikováno v:
Future Medicinal Chemistry. 12:183-192
Aim: Cancer is a major health burden and a leading cause of death worldwide. We sought to discover potential anticancer molecules with novel scaffold for further development of more active agents to address the issue. Methodology: A series of β-carb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8d9cfab42b1f949f515605f40556beb
https://doi.org/10.4155/fmc-2019-0276
https://doi.org/10.4155/fmc-2019-0276
Autor:
Yu-Sheng Chao, Tsung-Chih Hsieh, Teng-Kuang Yeh, Mao-Chia Yuan, Yu-Ling Huang, Chung-Yu Huang, Jinq-Chyi Lee, Chiung-Tong Chen, Chun-Hsu Yao, Min-Hsien Wang, Jen-Shin Song, Yu-Chen Huang, Szu-Huei Wu
Publikováno v:
European Journal of Medicinal Chemistry. 143:611-620
Treatment of hyperglycemia with drugs that block renal glucose reabsorption via inhibition of sodium-dependent glucose cotransporter 2 (SGLT2) is a novel approach to diabetes management. In this study, twenty-seven aryl C-glycosides bearing a C=N/C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb47cb983568428dd77525b02a056b9
https://doi.org/10.1016/j.ejmech.2017.11.019
https://doi.org/10.1016/j.ejmech.2017.11.019
Autor:
Kuang-Feng Chu, Chiung-Tong Chen, Szu-Huei Wu, Jen-Shin Song, Jinq-Chyi Lee, Chun-Hsu Yao, Wei-En Chang, Min-Hsien Wang, Yu-Sheng Chao, Teng-Kuang Yeh, Tsung-Chih Hsieh, Chung-Yu Huang
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:2242-2250
Suppression of glucose reabsorption through the inhibition of sodium-dependent glucose co-transporter 2 (SGLT2) is a promising therapeutic approach for the treatment of type 2 diabetes. To investigate the effect of C6-substitution on inhibition of SG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca79b37865ad6526ec8d1996a9f83b3d
https://doi.org/10.1016/j.bmc.2016.03.058
https://doi.org/10.1016/j.bmc.2016.03.058
Autor:
Yu-Sheng Chao, Jinq-Chyi Lee, Szu-Huei Wu, Tsung-Chih Hsieh, Chun-Hsu Yao, Kuang-Feng Chu, Teng-Kuang Yeh, Chiung-Tong Chen, Jen-Shin Song, Chung-Yu Huang, Min-Hsien Wang
Publikováno v:
Bioorganic chemistry. 83
Sodium-dependent glucose co-transporter 2 (SGLT2) inhibition has been demonstrated to efficiently control hyperglycemia via an insulin secretion-independent pathway. The unique mode of action eliminates the risk of hypoglycemia and makes SGLT2 inhibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc54b1577ca1a4ed60b0ef50900cb84
https://pubmed.ncbi.nlm.nih.gov/30469144
https://pubmed.ncbi.nlm.nih.gov/30469144
Autor:
Chuan Jen Wang, Amit A. Sadani, Hsin Pang Hsieh, Elizabeth A. Gullen, Yung-Chi Cheng, Chia-Yi Cheng, Yun Chen Tien, Jing Ma, Ming Chen Chou, Chun-Ping Chang, Yi Yu Ke, Chen Fu Lo, Lun K. Tsou, Tsung Chih Hsieh, Jiing Jyh Jan, Jen Shin Song, Yu Wei Liu, Ying Chieh Wong, Chia Hua Tsai, Chien Huang Wu, Kak Shan Shia
Publikováno v:
Journal of Medicinal Chemistry. 58:1452-1465
Motivated by the pivotal role of CXCR4 as an HIV entry co-receptor, we herein report a de novo hit-to-lead effort on the identification of subnanomolar purine-based CXCR4 antagonists against HIV-1 infection. Compound 24, with an EC50 of 0.5 nM agains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa19206a3e5b5af84e76abcf8c074d1b
https://doi.org/10.1021/jm501772w
https://doi.org/10.1021/jm501772w
Autor:
Chun-Jung Lin, Tzung-Sheng Lin, Pi-Hui Liang, Hsien-Wei Yeh, Jen-Shin Song, Ya-Wen Liw, Lih-Ching Hsu, Szu-Huei Wu, Tsung-Chih Hsieh
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:6282-6291
Novel C-aryl-d-glucofuranosides were synthesized and evaluated for their capacity to inhibit human sodium-dependent glucose co-transporter 2 (hSGLT2) and hSGLT1. Compound 21q demonstrated the best in vitro inhibitory activity against SGLT2 in this se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba36b6a8245636e6b0b3523aeb402668
https://doi.org/10.1016/j.bmc.2013.08.067
https://doi.org/10.1016/j.bmc.2013.08.067