Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Tsuneyuki Miyazaki"'
Autor:
Tsuneyuki Miyazaki, Yohei Shirakami, Taku Mizutani, Akinori Maruta, Takayasu Ideta, Masaya Kubota, Hiroyasu Sakai, Takashi Ibuka, Salvatore Genovese, Serena Fiorito, Vito Alessandro Taddeo, Francesco Epifano, Takuji Tanaka, Masahito Shimizu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract FXR is a member of the nuclear receptor superfamily and bile acids are endogenous ligands of FXR. FXR activation has recently been reported to inhibit intestinal inflammation and tumour development. This study aimed to investigate whether th
Externí odkaz:
https://doaj.org/article/7ce700ce2ce149d58144ddadc34ce01f
Autor:
Takayasu Ideta, Yohei Shirakami, Tsuneyuki Miyazaki, Takahiro Kochi, Hiroyasu Sakai, Hisataka Moriwaki, Masahito Shimizu
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 12, Pp 29207-29218 (2015)
Non-alcoholic fatty liver disease (NAFLD), which is strongly associated with metabolic syndrome, is increasingly a major cause of hepatic disorder. Dipeptidyl peptidase (DPP)-4 inhibitors, anti-diabetic agents, are expected to be effective for the tr
Externí odkaz:
https://doaj.org/article/ca44bf235ee3400aaabd8615461b6528
Autor:
Kenji Imai, Koji Takai, Tatsunori Hanai, Takayasu Ideta, Tsuneyuki Miyazaki, Takahiro Kochi, Atsushi Suetsugu, Makoto Shiraki, Masahito Shimizu
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 5, Pp 9612-9624 (2015)
The aim of this study was to determine whether skeletal muscle depletion predicts the prognosis of patients with hepatocellular carcinoma (HCC) that is being treated with sorafenib. We evaluated 40 consecutive HCC patients who received sorafenib trea
Externí odkaz:
https://doaj.org/article/de4f870287084b78b522e1968e12ff77
Autor:
Masahito Shimizu, Yohei Shirakami, Hiroyasu Sakai, Masaya Kubota, Takahiro Kochi, Takayasu Ideta, Tsuneyuki Miyazaki, Hisataka Moriwaki
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 3, Pp 6124-6139 (2015)
Hepatocellular carcinoma (HCC), which is a common malignancy worldwide, usually develops in a cirrhotic liver due to hepatitis virus infection. Metabolic syndrome, which is frequently complicated by obesity and diabetes mellitus, is also a critical r
Externí odkaz:
https://doaj.org/article/89bd6c0d4c3a49848e7f1d2b77f605b6
Autor:
Takashi Ibuka, Masaya Kubota, Takuji Tanaka, Francesco Epifano, Salvatore Genovese, Yohei Shirakami, Serena Fiorito, Taku Mizutani, Tsuneyuki Miyazaki, Takayasu Ideta, Vito Alessandro Taddeo, Akinori Maruta, Hiroyasu Sakai, Masahito Shimizu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
FXR is a member of the nuclear receptor superfamily and bile acids are endogenous ligands of FXR. FXR activation has recently been reported to inhibit intestinal inflammation and tumour development. This study aimed to investigate whether the novel F
Autor:
Takuji Tanaka, Hisataka Moriwaki, Takayasu Ideta, Takahiro Kochi, Masaya Kubota, Tsuneyuki Miyazaki, Hiroyasu Sakai, Masahito Shimizu, Yohei Shirakami
Publikováno v:
Oncotarget
Obesity and related metabolic abnormalities play a key role in liver carcinogenesis. Non-alcoholic steatohepatitis (NASH), which is often complicated with obesity and diabetes mellitus, is associated with the development of hepatocellular carcinoma (
Autor:
Sachiyo Ohnishi, Atsushi Suetsugu, Takayasu Ideta, Tsuneyuki Miyazaki, Kenji Imai, Hisataka Moriwaki, Takahiro Kochi, Makoto Shiraki, Masahito Shimizu, Koji Takai, Tatsunori Hanai
Publikováno v:
Hepatology Research. 46:743-751
Aim Sarcopenia impairs the outcome of patients with liver cirrhosis independently of liver function reserves. The aim of this study was to investigate whether the rate of skeletal muscle wasting predicts mortality in cirrhotic patients. Methods This
Autor:
Makoto Shiraki, Atsushi Suetsugu, Kenji Imai, Masahito Shimizu, Tatsunori Hanai, Koji Takai, Takayasu Ideta, Hisataka Moriwaki, Sachiyo Ohnishi, Takahiro Kochi, Tsuneyuki Miyazaki
Publikováno v:
Hepatology Research. 45:1083-1090
Aim Serum glycosylated Wisteria floribunda agglutinin positive Mac-2 binding protein (WFA(+) -M2BP) levels are a non-invasive and reliable marker to assess the degree of liver fibrosis. We investigated the use of WFA(+) -M2BP levels to predict mortal
Autor:
Yohei Shirakami, Masaya Kubota, Takuji Tanaka, Hisataka Moriwaki, Tomohiko Ohno, Takayasu Ideta, Hiroyasu Sakai, Masahito Shimizu, Takahiro Kochi, Tsuneyuki Miyazaki
Publikováno v:
Hepatology Research. 46:E201-E209
Aim Obesity and its related metabolic abnormalities, including oxidative stress and adipokine imbalance, are involved in liver carcinogenesis. The aim of the present study was to examine the effects of astaxanthin, a powerful biological antioxidant,
Autor:
Yusuke Suzuki, Eiichi Tomita, Tsuneyuki Miyazaki, Masahito Shimizu, Yoichi Nishigaki, Tatsunori Hanai, Shougo Shimizu, Kentarou Otsuji, Koji Takai, Takayasu Ideta, Kenji Imai, Hisataka Moriwaki, Hideki Hayashi
Publikováno v:
Hepatology Research. 45:514-522
AIM Transcatheter arterial chemoembolization (TACE) and transarterial infusion chemotherapy (TAI) are the main therapeutic strategies for treatment of advanced hepatocellular carcinoma (HCC). We conducted a randomized controlled trial to compare the