Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Tsuneo Takadera"'
Publikováno v:
Molecular Biology Reports. 48:4517-4525
Calcium ions mediate a variety of physiological responses of developing neurons including survival. The purpose of this study was to examine the effect of calcium influx through L-type calcium channels (LTCCs) or NMDA receptors on prostaglandin E2 (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cc63bb2199cd21ba61ed2572b7873b5
https://doi.org/10.1007/s11033-021-06472-0
https://doi.org/10.1007/s11033-021-06472-0
Autor:
Yuya Nakayama, Kayo Sugitani, Kazuhiro Ogai, Seiichi Matsugo, Tsuneo Takadera, Yoshiki Koriyama, Satoru Kato
Publikováno v:
Neuroscience Research. 77(1-2):87-96
Activated microglial cells play an important role in immune and inflammatory responses in CNS and play a role in neurodegenerative diseases. We examined the effects of lipoic acid (LA) on inflammatory responses of BV-2 microglial cells activated by l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b99e83e7e6b826160678b8f38dd4048
http://hdl.handle.net/2297/36255
http://hdl.handle.net/2297/36255
Autor:
Yoshiki Koriyama, Kazuhiro Ogai, Kunizo Arai, Tsuneo Takadera, Marie Kamiya, Satoru Kato, Kayo Sugitani
Publikováno v:
Neurochemistry International. 61:1242-1253
Nipradilol (Nip), which has α1- and β-adrenoceptor antagonist and nitric oxide (NO)-donating properties, has clinically been used as an anti-glaucomatous agent in Japan. NO mediates cellular signaling pathways that regulate physiological functions.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d00dca5128368fa65983d1ec03e89b
https://doi.org/10.1016/j.neuint.2012.09.004
https://doi.org/10.1016/j.neuint.2012.09.004
Publikováno v:
Neurotoxicity Research. 21:309-316
In the central nervous system, members of the Src family of tyrosine kinases (SFKs) are widely expressed and are abundant in neurons. The purpose of this study is to examine whether glycogen synthase-3 (GSK-3) is involved in SFK inhibitor-induced apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42db232eec3545bfd391bac7e704efe
https://doi.org/10.1007/s12640-011-9284-5
https://doi.org/10.1007/s12640-011-9284-5
Publikováno v:
Cellular and Molecular Neurobiology. 30:193-198
Calcium ion is a secondary messenger that mediates a variety of physiological responses of neurons, including cell survival responses. To determine the role of calcium in regulating neuronal survival and death, we examined whether chelation of extrac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df5a6c6f0b975ed36ee538aed2e4a27
https://doi.org/10.1007/s10571-009-9442-y
https://doi.org/10.1007/s10571-009-9442-y
Autor:
Tsuneo Takadera, Takao Ohyashiki
Publikováno v:
Journal of Biomedical Science. 15:767-770
The purpose of this study is to examine whether benzyl alcohol affects N-methyl-D-aspartate (NMDA) receptor in cortical cells. Benzyl alcohol (0.5-2 mM) inhibited NMDA-induced cytotoxicity. The protective effect of benzyl alcohol on NMDA-induced toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e035ad9e89912eaf9143e25b50c63846
https://doi.org/10.1007/s11373-008-9276-5
https://doi.org/10.1007/s11373-008-9276-5
Autor:
Tsuneo Takadera, Takao Ohyashiki
Publikováno v:
Brain Research. 1133:20-26
Calcineurin is selectively enriched within neurons of the central nervous system. The mechanism of calcineurin inhibitor-induced neurotoxicity remains poorly understood. The purpose of this study is to examine whether glycogen synthase-3 (GSK-3) is i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a91301e2ff41f848aa0a41b1b1f352
https://doi.org/10.1016/j.brainres.2006.11.037
https://doi.org/10.1016/j.brainres.2006.11.037
Autor:
Takao Ohyashiki, Tsuneo Takadera
Publikováno v:
Life Sciences. 78:1878-1883
The activation of glutamate receptors, particularly N-methyl-D-aspartate (NMDA) receptors, initiates ischemic cascade in the early stages of cerebral ischemia. Postischemia, cerebral ischemia is also associated with an inflammatory reaction that cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49cc3e9634e770f609ad9ae43a961d8
https://doi.org/10.1016/j.lfs.2005.08.026
https://doi.org/10.1016/j.lfs.2005.08.026
Publikováno v:
Toxicology and Applied Pharmacology. 210:100-107
Recent data suggest that anesthetic drugs cause neurodegeneration during development. Ketamine is frequently used in infants and toddlers for elective surgeries. The purpose of this study is to determine whether glycogen synthase kinase-3 (GSK-3) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ebd45220b9798964277f9ec38a128f
https://doi.org/10.1016/j.taap.2005.10.005
https://doi.org/10.1016/j.taap.2005.10.005
Publikováno v:
Biological & Pharmaceutical Bulletin. 28(6):941-946
Exposure of rat phenochromocytoma cells (PC12 cells) to aluminum maltolate complex, Al(maltol)3, induced a decrease in intracellular glutathione (GSH) concentration, resulting in a facilitated release of lactate dehydrogenase (LDH) from the cell and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1c5a4b6d3d352ffb8f984a859aafd7
http://id.nii.ac.jp/1247/00000509/
http://id.nii.ac.jp/1247/00000509/