Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Tsuneo KOSAZUMA"'
Publikováno v:
Congenital Anomalies. 34:183-191
The maxillary regions of day-12.5 and day-13.5 ICR mouse fetuses were cultivated in a chemically-defined serumless medium by a suspension culture technique to examine the toxic effects of 5-fluorouracil (5-FU) and hydroxyurea (HU) on cultured palates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ae87f40ce092f23b1e44b8dd799662e
https://doi.org/10.1111/j.1741-4520.1994.tb00601.x
https://doi.org/10.1111/j.1741-4520.1994.tb00601.x
Publikováno v:
Cells Tissues Organs. 137:59-64
Explanted palates of day 12 and day 13 mouse fetuses were cultured in a chemically defined serumless medium for 48–72 h by a suspension culture technique. The palate of day 12 fetuses closed successfully within 72 h and that of day 13 fetuses withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d9db2f1c38e4dad3bb904775361800
https://doi.org/10.1159/000146859
https://doi.org/10.1159/000146859
Publikováno v:
Congenital anomalies. 44(2)
Using in vitro organ culture of the fetal mouse palate in a chemically defined serumless medium, the toxicity of 24 chemical compounds was investigated. Explanted palates of day-12.5 mouse fetuses were exposed for 72 h in vitro to various concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e4b97d23034ff99c152411a8059ad1
https://pubmed.ncbi.nlm.nih.gov/15198718
https://pubmed.ncbi.nlm.nih.gov/15198718
Autor:
Tsuneo Kosazuma, Toshiya Takigawa, Ming-Jen Chou, Shigehito Yamada, Sachiko Takahara, Kohei Shiota
Publikováno v:
Anatomy and embryology. 208(1)
Day-13 fetal mouse palates (plug day=day 0) were labeled with carbon particles at various sites of palatal shelves and cultivated in a chemically defined medium for up to 48 h. During the culture period, the bilateral palatal shelves came in contact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a1cc200f3142e56c501b633228cc0e
https://pubmed.ncbi.nlm.nih.gov/14986130
https://pubmed.ncbi.nlm.nih.gov/14986130
Autor:
Saju Kawauchi, Tsuneo Kosazuma
Publikováno v:
The Journal of toxicological sciences. 19(4)
The maxillary regions of day-12.5 ICR mouse fetuses were cultured in a chemically-defined serumless medium and the effects of methylxanthine derivatives on cultured palates were studied. Explanted palates were treated for 72 hr in vitro with 0.5-2 mM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf31ea21b39da8a115adde1ab5f3754
https://pubmed.ncbi.nlm.nih.gov/7884827
https://pubmed.ncbi.nlm.nih.gov/7884827
Autor:
Ichiro Makita, Hajime Shimazu, Toshifumi Hayashi, Kyoichi Takeda, Takashi Hashi, Tsuneo Kosazuma
Publikováno v:
The Journal of Toxicological Sciences. 3:87-107
Subacute toxicity test of AMI-U-II was carried out using male and female JCL:SD rats. The animals were given intravenously AMI-U-II(80, 40 and 20ml/kg) or reference solution (80 and 40ml/kg) for five weeks. Tachypnea, depression of spontaneous activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2929a681646cc853e209a32fd852775c
https://doi.org/10.2131/jts.3.87
https://doi.org/10.2131/jts.3.87
Publikováno v:
The Journal of Toxicological Sciences. 3:69-86
M73101 was given orally to pregnant mice (0, 100, 400 and 800mg/kg/day) and rats (0, 100, 300 and 600mg/kg/day) during the major organo-genesis to assess the influences of prenatal and postnatal development of progeny. There were no apparent effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03818930681f85e0da5b1366cd00c348
https://doi.org/10.2131/jts.3.69
https://doi.org/10.2131/jts.3.69
Autor:
Tsuneyoshi Tanabe, Mieko Iwata, Hiroko Togashi, Kazue Hiraga, Kotaro Shimpo, Noriko Mori, Masayo Takahashi, Hajime Shimazu, Tsuneo Kosazuma
Publikováno v:
The Journal of Toxicological Sciences. 4:139-161
By using male and female JCL:SD rats, the subacute toxicity and recovery from toxic phenomena were tested on M73101, which was newly developed as an analgesic and anti-inflammatory drug. The drug was compulsively administered perorally in doses of 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9a7c812ee8b6ba102f0ce417bcce247
https://doi.org/10.2131/jts.4.139
https://doi.org/10.2131/jts.4.139
Autor:
Hiroko Togashi, Tsuneyoshi Tanabe, Kotaro Shimpo, Hajime Shimazu, Noriko Mori, Masayo Takahashi, Tsuneo Kosazuma, Kazue Hiraga, Nobuko Aoki
Publikováno v:
The Journal of Toxicological Sciences. 4:255-277
Chronic toxicity and recovery tests of M73101, a new analgesic and antiinflammatory agent, were carried out using male and female JCL:SD rats. The drug was orally administered in doses of 0, 10, 30, 100, 300 and 1000mg/kg body weight/day for six mont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d4a98ac8cb96df67189b7101b18de13
https://doi.org/10.2131/jts.4.255
https://doi.org/10.2131/jts.4.255
Publikováno v:
The Journal of toxicological sciences. 4(2)
Pregnant female rats were given orally M73101 (0, 100, 250 and 600 mg/kg) or aspirin (225 mg/kg) on gestational days 7 to 17. About two-thirds of treated females in each group were sacrificed at day 21 of pregnancy and their fetuses were examined for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4c79cb80fd918fcf7ba1d775961d810
https://pubmed.ncbi.nlm.nih.gov/315475
https://pubmed.ncbi.nlm.nih.gov/315475