Zobrazeno 1 - 10 of 12 pro vyhledávání: '"Tsuneo Iwakawa"'
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ChemInform Abstract: Reaction of 3-Acetonyl-5-cyano-1,2,4-thiadiazole with Phenylhydrazine Hydrochlorides: Indolization and Phenylpyrazolation
Autor: Tsuneo Iwakawa, Akira Murabayashi, Giichi Sugimori, Hiroshi Nakai
Publikováno v: ChemInform. 31
Treatment of 3-acetonyl-5-cyano-1, 2, 4-thiadiazole (1) with 4-methyl or 4-methoxyphenylhydrazine hydrochloride provided 5-cyano-3-(2, 5-dimethylindol-3-yl)-1, 2, 4-thiadiazole (2) or 5-cyano-3-(5-methoxy-2-methylindol-3-yl)-1, 2, 4-thiadiazole (3) a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d6915979b6f8451262c4e066124a485
https://doi.org/10.1002/chin.200025057
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3
Reaction of 3-Acetonyl-5-cyano-1,2,4-thiadiazole with Phenylhydrazine Hydrochlorides: Indolization and Phenylpyrazolation
Autor: Tsuneo Iwakawa, Hiroshi Nakai, Akira Murabayashi, Giichi Sugimori
Publikováno v: Chemical and Pharmaceutical Bulletin. 48:160-162
Treatment of 3-acetonyl-5-cyano-1, 2, 4-thiadiazole (1) with 4-methyl or 4-methoxyphenylhydrazine hydrochloride provided 5-cyano-3-(2, 5-dimethylindol-3-yl)-1, 2, 4-thiadiazole (2) or 5-cyano-3-(5-methoxy-2-methylindol-3-yl)-1, 2, 4-thiadiazole (3) a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94497341e796f42e6387eaef9c6873c
https://doi.org/10.1248/cpb.48.160
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4
Cycloaddition in Synthesis of Sulfonamide Derivatives. IV. One-Pot Synthesis of 3-Dimethylamino-4,1,2-benzoxathiazine 1,1-Dioxides, 3-Methoxy-4-methyl-1,2,4-benzothiadiazine 1,1-Dioxide and 3-Dimethylamino-1,4,2-benzodithiazine 1,1-Dioxides
Autor: Hiroto Tamura, Yoshio Hayase, Akira Murabayashi, Tsuneo Iwakawa
Publikováno v: Chemical and Pharmaceutical Bulletin. 39:1939-1943
A novel, one-pot synthesis of 3-dimethylamino-4, 1, 2-benzoxathiazine 1, 1-dioxides (7), 3-methoxy-4-methyl-1, 2, 4-benzothiadiazine 1, 1-dioxide (9) and 3-dimethylamino-1, 4, 2-benzodithiazine 1, 1-dioxides (11) is described. The procedure in the ca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2965d4d5f086777705e30b6004613315
https://doi.org/10.1248/cpb.39.1939
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5
HU0622: a small molecule promoting GAP-43 activation and neurotrophic effects
Autor: Ken-Ichiro Uwabe, Kiyoshi Nagata, Mitsunobu Matsumoto, Koji Talkahashi, Tsuneo Iwakawa
Publikováno v: Neuropharmacology. 51(4)
During the course of neuronal development or regeneration, the axonal growth cone protein growth-associated protein 43 (GAP-43) is expressed in a great majority of differentiating neurons, suggesting that the regulation of this gene is tied to import
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea270c68811f27e138c028a06b5deb08
https://pubmed.ncbi.nlm.nih.gov/16806303
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6
A new galloylglucoside from Cleyera ochnacea DC
Autor: Akira Takashima, Tsuneo Iwakawa, Yoshimi Tanaka
Publikováno v: Chemicalpharmaceutical bulletin. 49(11)
A new galloylglucoside, 3-hydroxy-5-methylphenol 1-O-beta-D-(6'-galloyl)glucopyranoside (1) was isolated from Cleyera ochnacea DC. (Theaceae). Its structure was elucidated on the basis of chemical and spectral analysis. Compound 1 showed inhibitory a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a90061355b81d86e38eea1f2309a429
https://pubmed.ncbi.nlm.nih.gov/11724249
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7
Cycloaddition in synthesis of sulfonamide derivatives. II. Synthesis of N-arylsulfonylethoxalamides by cycloaddition of arylsulfonyl isocyanates to ethyl oxamates
Autor: Hiroto Tamura, Tsuneo Iwakawa, Yoshio Hayase
Publikováno v: Chemical and Pharmaceutical Bulletin. 38:1069-1071
A new class of sulfonamides, N2-arylsulfonyl-N1, N1-disubstituted ethoxalamidines, was synthesized by reaction of arylsulfonyl isocyanates with N, N-disubstituted ethyl oxamates. It was suggested that the reacion might proceed through [2+2] cycloaddi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5656b29b41c735afc9fae76375cf5bd2
https://doi.org/10.1248/cpb.38.1069
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9
Cycloaddition in synthesis of sulfonamide derivatives. III. Convenient synthesis of 3-alkylthio-4H-1,2,4-benzothiadiazine 1,1-dioxides
Autor: Tsuneo Iwakawa, Yoshio Hayase, Hiroto Tamura
Publikováno v: Chemical and Pharmaceutical Bulletin. 38:1075-1076
Synthesis of 3-alkylthio-4-methyl-4H-1, 2, 4-benzothiadiazine 1, 1-dioxides was conveniently achieved by [2+2] cycloaddition reaction of S-alkyl N-methyl-N-phenyldithiocarbamates with chlorosulfonyl isocyanate with subsequent loss of carbonyl sulfide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ee5537e2bf9c6bc04ff093ddbca0e07
https://doi.org/10.1248/cpb.38.1075
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10
Cycloaddition in Synthesis of Sulfonamide Derivatives. VI Unexpected Products from the Reaction of Dithiocarbamate with Chlorosulfonyl Isocyanate a Novel Synthetic Route to 5-Amino-1,2,4-dithiazol-3-one and N,N-Disubstituted N'-Chlorosulfonylcarbamimidoyl Chloride
Autor: Tsuneo Iwakawa, Akira Murabayashi, Tomohiro Sato
Publikováno v: HETEROCYCLES. 38:1015
Reaction of propyl N-methyl-N-phenyldithiocarbamate (1a) with chlorosulfonyl isocyanate in the presence of AlCl3 gives 5-(N-methylanilino)-1,2,4- dithiazol-3-one (2), 1-methyl-2-propylthio-4-quinazolinone (3) and N-methyl-N- phenyl-S-propylthiocarbam
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44c12bb2bb4097fbf869e19d380a9d87
https://doi.org/10.3987/com-93-6641
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