Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Tsuneaki Hida"'
Autor:
Andrew S. Judd, Tsuneaki Hida, Philippe Breton, Stephen F. Martin, Philip R. Kym, Masayuki Yamashita, Erica Kraynack, Paul J. Hergenrother, W.‐C. Lee, Michael S. Loft, Anne V. Hodgson
Publikováno v:
Tetrahedron. 63:5709-5729
We report the details of the first total synthesis of erythromycin B using two different strategies for the end game. The first of these follows a classical approach in which the desosamine and cladinose residues are sequentially appended to a macroc
Publikováno v:
The Journal of Antibiotics. 48:12-20
We detected potent angiostatic activity in a MeOH extract from the mycelia of microbial strain S-45628 in the chick chorioallantoic membrane (CAM) assay. The producer was taxonomically characterized as Streptomyces purpurascens. Active principles des
Autor:
Tsuneaki Hida, Masayuki Takizawa, Akiko Hiramoto, Takashi Horiguchi, Seiichi Tanida, Setsuo Harada
Publikováno v:
The Journal of Antibiotics. 48:579-588
The microbial lipopeptides, TAN-1511 A, B and C, were isolated from the culture broth of Streptosporangium amethystogenes subsp. fukuiense AL-23456. Their structures were elucidated on the basis of their reactions and spectroscopic analyses. These li
Autor:
Seiichi Tanida, Kozo Hayashi, Setsuo Harada, Noriaki Kawamura, Tsuneaki Hida, Koichi Yukishige
Publikováno v:
The Journal of Antibiotics. 48:589-603
TAN-1511 analogues were synthesized and their effects on the proliferation of bone marrow cells were examined. To exert potent activity the following conditions are necessary: the configuration of the 2-amino-6, 7-dihydroxy-4-thiaheptanoic acid moiet
Publikováno v:
International Journal of Immunopharmacology. 16:67-74
Sperabillin polymers, which have been shown recently to have antitumor activity, are new basic peptidyl polymers composed of a pseudo-peptide antibiotic, sperabillin A. The polymers, HP-2 (MW 9990), AP-2 (MW 20,100) and AB-2 (MW 35,000), were found t
Publikováno v:
Bulletin of the Chemical Society of Japan. 66:863-869
Sperabillins, novel antibiotics, were isolated from the culture filtrate of Pseudomonas fluorescens YK-437. The structure of sperabillin A was elucidated to be 3-[[(3R,5R)-3-amino-6-[(2E,4Z)-2,4-hexadienoylamino]-5-hydroxyhexanoyl]amino]propanamidine
Autor:
Yoshio Kozai, Shigetoshi Tsubotani, Morio Murakami, Akira Hori, Setsuo Harada, Tsuneaki Hida, Hideaki Natsugari
Publikováno v:
Chemical and Pharmaceutical Bulletin. 41:889-893
Sperabillin A, 3-[[(3R, 5R)-3-amino-6-[(2E, 4Z)-2, 4-hexadienoylamino]-5-hydroxyhexanoyl]amino]propanamidine dihydrochloride, was polymerized on standing for several days under a highly humid atmosphere or in the presence of radical initiators. The a
Publikováno v:
ChemInform. 24
Sperabillins, novel antibiotics, were isolated from the culture filtrate of Pseudomonas fluorescens YK-437. The structure of sperabillin A was elucidated to be 3-[[(3R,5R)-3-amino-6-[(2E,4Z)-2,4-hexadienoylamino]-5-hydroxyhexanoyl]amino]propanamidine
Publikováno v:
ChemInform. 26
Dnacin A1 and B1 were revealed to be new naphthyridinomycin-type antitumor antibiotics with formulae of C20H23N5O4 and C19H24N4O5, respectively. The gross structure of dnacin A1 was elucidated by the spectroscopic analyses. Conversion of dnacin B1 in
Autor:
Atsushi Kakinuma, Yumiko Kitamura, Shigemi Iinuma, Tsuneo Asano, Takaki Hayakawa, Koichi Kato, Makoto Kobayashi, Kunio Matsuoka, Tsuneaki Hida
Publikováno v:
ChemInform. 25
Four kinds of retrovirus protease inhibitors (RPI-856 A, B, C and D) were isolated as white powder from the culture filtrate of a soil isolate, Streptomyces sp. AL-322 by column chromatography using Diaion HP-20, Sephadex LH-20, ODS reversed phase HP