Zobrazeno 1 - 5 of 5 pro vyhledávání: '"Tsun Sing, Chow"'
2
Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2)
Autor: Larry M.C. Chow, Chin-Fung Chan, Man Chun Law, Xuezhen Zhu, Tsz Cheung Chong, Zhen Liu, Tsun Sing Chow, Jiahua Cui, Kin-Fai Chan, Tak Hang Chan, Iris L. K. Wong
Publikováno v: Journal of Medicinal Chemistry. 64:14311-14331
We synthesize various substituted triazole-containing flavonoids and identify potent, nontoxic, and highly selective BCRP inhibitors. Ac18Az8, Ac32Az19, and Ac36Az9 possess m-methoxycarbonylbenzyloxy substitution at C-3 of the flavone moiety and subs
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e263f6d662e83c7fb1095f6382fe523f
https://doi.org/10.1021/acs.jmedchem.1c00779
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3
Disruption of SND1–MTDH Interaction by a High Affinity Peptide Results in SND1 Degradation and Cytotoxicity to Breast Cancer Cells In Vitro and In Vivo
Autor: Teng Chen, Xiaochun Su, Tak Hang Chan, Wenqin Sun, Peng Li, Tsun Sing Chow, Larry M.C. Chow, Iris L. K. Wong, Kit Ying Choy, Xinqing Yang, Yunjiao He
Publikováno v: Molecular Cancer Therapeutics. 20:76-84
Staphylococcal nuclease domain-containing protein 1 (SND1) is a multifunctional oncoprotein overexpressed in breast cancer. Binding of metadherin (MTDH) to SND1 results in the stabilization of SND1 and is important in the initiation and progression o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b68c0524d4e66e32addbca589c8a5fbf
https://doi.org/10.1158/1535-7163.mct-20-0130
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4
Disruption of SND1-MTDH Interaction by a High Affinity Peptide Results in SND1 Degradation and Cytotoxicity to Breast Cancer Cells
Autor: Peng, Li, Yunjiao, He, Teng, Chen, Kit-Ying, Choy, Tsun Sing, Chow, Iris L K, Wong, Xinqing, Yang, Wenqin, Sun, Xiaochun, Su, Tak-Hang, Chan, Larry M C, Chow
Publikováno v: Molecular cancer therapeutics. 20(1)
Staphylococcal nuclease domain-containing protein 1 (SND1) is a multifunctional oncoprotein overexpressed in breast cancer. Binding of metadherin (MTDH) to SND1 results in the stabilization of SND1 and is important in the initiation and progression o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a7899791e4970e3f13c88ae835fc466f
https://pubmed.ncbi.nlm.nih.gov/33268570
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