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pro vyhledávání: '"Tsun Ming Lok"'
Publikováno v:
Oncogene. 39:2819-2834
Mitotic slippage involves cells exiting mitosis without proper chromosome segregation. Although degradation of cyclin B1 during prolonged mitotic arrest is believed to trigger mitotic slippage, its upstream regulation remains obscure. Whether mitotic
Publikováno v:
Oncogene
Mitotic slippage involves cells exiting mitosis without proper chromosome segregation. Although degradation of cyclin B1 during prolonged mitotic arrest is believed to trigger mitotic slippage, its upstream regulation remains obscure. Whether mitotic
Publikováno v:
Cell Death and Disease, Vol 10, Iss 4, Pp 1-15 (2019)
Cell Death & Disease
Cell Death & Disease
Disrupting microtubule dynamics with spindle poisons activates the spindle-assembly checkpoint (SAC) and induces mitotic cell death. However, mitotic exit can occur prematurely without proper chromosomal segregation or cytokinesis by a process termed