Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Tsun Leung, Chan"'
Autor:
Ava Kwong, Cecilia Yuen Sze Ho, Vivian Yvonne Shin, Chun Hang Au, Tsun-Leung Chan, Edmond Shiu Kwan Ma
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Background The popularity of multigene testing increases the probability of identifying variants of uncertain significance (VUS). While accurate variant interpretation enables clinicians to be better informed of the genetic risk of their pat
Externí odkaz:
https://doaj.org/article/7783bc06d4f8473ebd28c6a2080cce23
Autor:
Wai Sing Chan, Yuk Man Lam, Janet Hei Yin Law, Tsun Leung Chan, Edmond Shiu Kwan Ma, Bone Siu Fai Tang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract We extracted one-year genomic data (August 2020–July 2021) from GISAID EpiCoV™ database and estimated monthly proportions of 11 SARS-CoV-2 variants in various geographical regions. From continental perspective, Delta VOC predominated in
Externí odkaz:
https://doaj.org/article/688128d455f644a8b77f956352f6ef2d
Publikováno v:
Biomedicines, Vol 11, Iss 9, p 2344 (2023)
The goal of this study was to evaluate the performance of a commercial reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay (Detect COVID-19 Test) in the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2
Externí odkaz:
https://doaj.org/article/8248eebd18cd479c9b1994f1ed267bc0
Autor:
Ava Kwong, Cecilia Yuen Sze Ho, Vivian Yvonne Shin, Chun Hang Au, Wing Pan Luk, Ling Hiu Fung, Tsun‐Leung Chan, Karen Kar Loen Chan, Hextan Yuen Sheung Ngan, Edmond Shiu Kwan Ma
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 10, Iss 7, Pp n/a-n/a (2022)
Abstract Background Ovarian and breast cancers are known to have significant genetic components. Considering the differences in the mutation spectrum across ethnicity, it is important to identify hereditary breast and ovarian cancer (HBOC) genes muta
Externí odkaz:
https://doaj.org/article/0824d0fd5fc744bca7f83b5f4a1a44ff
Autor:
Ava Kwong, Vivian Yvonne Shin, Cecilia Y. S. Ho, Chun Hang Au, Thomas P. Slavin, Jeffrey N. Weitzel, Tsun-Leung Chan, Edmond S. K. Ma
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Germline TP53 mutations are associated with Li-Fraumeni syndrome, a severe and rare hereditary cancer syndrome. Despite the rarity of germline TP53 mutations, the clinical implication for mutation carriers and their families is si
Externí odkaz:
https://doaj.org/article/00741944e70547149fff3695430a3e4a
Autor:
Wai Sing Chan, Chun Hang Au, Yvonne Chung, Henry Chi Ming Leung, Dona N. Ho, Elaine Yue Ling Wong, Tak Wah Lam, Tsun Leung Chan, Edmond Shiu Kwan Ma, Bone Siu Fai Tang
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-7 (2020)
Abstract Objective We designed and tested a Nanopore sequencing panel for direct tuberculosis drug resistance profiling. The panel targeted 10 resistance-associated loci. We assessed the feasibility of amplifying and sequencing these loci from 23 cli
Externí odkaz:
https://doaj.org/article/af72930adee84b7f87ab0e4890f02345
Autor:
Wai Sing Chan, Tsun Leung Chan, Chun Hang Au, Chin Pang Leung, Man Yan To, Man Kin Ng, Sau Man Leung, May Kwok Mei Chan, Edmond Shiu Kwan Ma, Bone Siu Fai Tang
Publikováno v:
Diagnostic Pathology, Vol 15, Iss 1, Pp 1-18 (2020)
Abstract Background Human papillomavirus (HPV) testing has been employed by several European countries to augment cytology-based cervical screening programs. A number of research groups have demonstrated potential utility of next-generation sequencin
Externí odkaz:
https://doaj.org/article/283a96f2d0344ea2a8c1ab1b98ca1d26
Autor:
Wai Sing Chan, Chun Hang Au, Sau Man Leung, Dona N. Ho, Elaine Yue Ling Wong, Man Yan To, Man Kin Ng, Tsun Leung Chan, Edmond Shiu Kwan Ma, Bone Siu Fai Tang
Publikováno v:
Diagnostic Pathology, Vol 15, Iss 1, Pp 1-7 (2020)
Abstract Background Diversified etiology of lower respiratory tract infection renders diagnosis challenging. The mainstay microbial culture is time-consuming and constrained by variable growth requirements. In this study, we explored the use of Nanop
Externí odkaz:
https://doaj.org/article/2af95a2e6acc4d30aaaf66675b1b72dc
Autor:
Ricky Y. T. Chiu, Noah Kojima, Garrett L. Mosley, Kwok Kin Cheng, David Y. Pereira, Matthew Brobeck, Tsun Leung Chan, Jonpaul Sze-Tsing Zee, Harsha Kittur, Cheuk Yiu Tenny Chung, Eric Tsang, Kajal Maran, Raymond Wai-Hung Yung, Alex Chin-Pang Leung, Ryan Ho-Ping Siu, Jessica Pui-Ling Ng, Tsz Hei Choi, Mei Wai Fung, Wai Sing Chan, Ho Yin Lam, Koon Hung Lee, Sean Parkin, Felix C. Chao, Stephen Ka-Nung Ho, Daniel R. Marshak, Edmond Shiu-Kwan Ma, Jeffrey D. Klausner
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
ABSTRACT As the COVID-19 pandemic progresses, there is an increasing need for rapid, accessible assays for SARS-CoV-2 detection. We present a clinical evaluation and real-world implementation of the INDICAID COVID-19 rapid antigen test (INDICAID rapi
Externí odkaz:
https://doaj.org/article/356fa2dd893c4f01a0719a006dd47bfb
Autor:
Sze-Tsing Zee, Lam-Fung Kwok, Ka-Man Kee, Ling-Hiu Fung, Wing-Pan Luk, Tsun-Leung Chan, Chin-Pang Leung, Pik-Wa Yu, Jhan Hung, Kit-Ying SzeTo, Wai-Leng Chan, Siu-Fai Tang, Wai-Chi Lin, Shiu-Kwan Ma, Koon-Hung Lee, Chor-Chiu Lau, Wai-Hung Yung
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1322 (2022)
Immune escape is observed with SARS-CoV-2 Omicron (Pango lineage B.1.1.529), the predominant circulating strain worldwide. A booster dose was shown to restore immunity against Omicron infection; however, real-world data comparing mRNA (BNT162b2; Comi
Externí odkaz:
https://doaj.org/article/b27532d2cc504d3db104a461a3309c2b