PE.Ma-061 - L’induction précoce de la surexpression de l’interféron-alpha 1 murin in vivo induit une expansion de lymphocytes T régulateurs hautement suppressifs qui protègent contre l’arthrite expérimentale

Autor: Matyja, K. ⁽¹⁾, Ribon, M. ⁽¹⁾, Hervé, R. ⁽¹⁾, Lemeiter, D. ⁽¹⁾, Tsumiyama, K. ⁽²⁾, Shiozawa, S. ⁽²⁾, Bessis, N. ⁽¹⁾, Boissier, M.C. ⁽³⁾, Decker, P. ⁽¹⁾

Publikováno v: In Revue du rhumatisme November 2016 83 Supplement 1:A301-A302

DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus.

Autor: Shiozawa S; Institute for Rheumatic Diseases, 944-25 Fujita, Katoshi 673-1462, Japan.; Department of Medicine, Kyushu University Beppu Hospital, 4546 Tsurumihara, Beppu 874-0838, Japan.; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan.; Department of Medicine, Rheumatology and Orthopedic Surgery, Matsubara Mayflower Hospital, 944-25 Fujita, Katoshi 673-1462, Japan., Tsumiyama K; Institute for Rheumatic Diseases, 944-25 Fujita, Katoshi 673-1462, Japan.; Department of Medicine, Kyushu University Beppu Hospital, 4546 Tsurumihara, Beppu 874-0838, Japan.; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan.; Department of Medicine, Rheumatology and Orthopedic Surgery, Matsubara Mayflower Hospital, 944-25 Fujita, Katoshi 673-1462, Japan., Miyazaki Y; Department of Medicine, Kyushu University Beppu Hospital, 4546 Tsurumihara, Beppu 874-0838, Japan.; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan., Uto K; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan., Sakurai K; Institute for Rheumatic Diseases, 944-25 Fujita, Katoshi 673-1462, Japan.; Department of Medicine, Kyushu University Beppu Hospital, 4546 Tsurumihara, Beppu 874-0838, Japan., Nakashima T; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan., Matsuyama H; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan., Doi A; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan., Tarui M; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan., Izumikawa M; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan., Kimura M; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan., Fujita Y; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan., Satonaka C; Division of Bioregulation, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Sumaku, Kobe 654-0142, Japan., Horiuchi T; Department of Medicine, Kyushu University Beppu Hospital, 4546 Tsurumihara, Beppu 874-0838, Japan., Matsubara T; Department of Medicine, Rheumatology and Orthopedic Surgery, Matsubara Mayflower Hospital, 944-25 Fujita, Katoshi 673-1462, Japan., Oribe M; Oribe Clinic, 1-8-15 Higashi-Odori, Oita 870-0823, Japan., Yamane T; Department of Rheumatology, Kakogawa City Hospital, 439 Honmachi, Kakogawa 675-8611, Japan., Kagawa H; Department of Medicine, Red Cross Society Himeji Hospital, 1-12-1 Shimoteno, Himeji 670-8540, Japan., Li QZ; Department of Immunology, University of Texas Southwestern Medical Center, 6001 Forest Park Road/ND 6.504, Dallas, TX 75390-8814, USA., Mizuno K; Drug Discovery Platform, KAN Research Institute, Inc., 6-8-2 Minatojimaminamicho, Kobe 650-0047, Japan., Mukai Y; Drug Discovery Platform, KAN Research Institute, Inc., 6-8-2 Minatojimaminamicho, Kobe 650-0047, Japan., Murakami K; Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsujima, Aobaku 981-8558, Japan., Enya T; Department of Immunology, Kindai University Faculty of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan.; Department of Pediatrics, Kindai University Faculty of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan., Tsukimoto S; Department of Immunology, Kindai University Faculty of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan.; Department of Anesthesiology, Kindai University Faculty of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan., Hakata Y; Department of Immunology, Kindai University Faculty of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan., Miyazawa M; Department of Immunology, Kindai University Faculty of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan.; Kindai University Anti-Aging Center, 3-4-1 Kowakae, Higashi-Osaka, Osaka 577-8502, Japan., Shiozawa K; Department of Medicine, Rheumatology and Orthopedic Surgery, Matsubara Mayflower Hospital, 944-25 Fujita, Katoshi 673-1462, Japan.; Rheumatology and Collagen Disease Center, Hyogo Prefectural Kakogawa Medical Center, 203 Kanno, Kakogawa 675-8555, Japan.

Publikováno v: IScience [iScience] 2021 Dec 02; Vol. 25 (1), pp. 103537. Date of Electronic Publication: 2021 Dec 02 (Print Publication: 2022).

Conditional Upregulation of IFN-α Alone Is Sufficient to Induce Systemic Lupus Erythematosus.

Autor: Akiyama C; Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142, Japan., Tsumiyama K; Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142, Japan.; Institute for Rheumatic Diseases, Ashiya 659-0004, Japan.; Kyushu University Beppu Hospital, Beppu 874-0838, Japan; and., Uchimura C; Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142, Japan., Honda E; Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142, Japan., Miyazaki Y; Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142, Japan., Sakurai K; Institute for Rheumatic Diseases, Ashiya 659-0004, Japan.; Kyushu University Beppu Hospital, Beppu 874-0838, Japan; and., Miura Y; Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142, Japan., Hashiramoto A; Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142, Japan., Felsher DW; Division of Oncology, Department of Medicine and Pathology, School of Medicine, Stanford University, Stanford, CA 94305., Shiozawa S; Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142, Japan; shiozawa@port.kobe-u.ac.jp.; Institute for Rheumatic Diseases, Ashiya 659-0004, Japan.; Kyushu University Beppu Hospital, Beppu 874-0838, Japan; and.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2019 Aug 15; Vol. 203 (4), pp. 835-843. Date of Electronic Publication: 2019 Jul 19.

A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell.

Autor: Hashiramoto A; From the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142., Konishi Y; From the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142., Murayama K; From the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142., Kawasaki H; From the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142., Yoshida K; From the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142., Tsumiyama K; the Department of Medicine, Rheumatic Diseases Unit, Kyushu University Beppu Hospital, Beppu 874-0838., Tanaka K; From the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142., Mizuhara M; From the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142., Shiotsuki T; From the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142., Kitamura H; From the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142., Komai K; From the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142., Kimura T; the Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, 3190 Gofuku, 930-0194 Toyama., Yagita H; the Department of Immunology, Juntendo University School of Medicine, Tokyo 113-8431, and., Shiozawa K; the Department of Rheumatology, Hyogo Prefectural Kakogawa Medical Center, Kakogawa 675-8555, Japan., Shiozawa S; the Department of Medicine, Rheumatic Diseases Unit, Kyushu University Beppu Hospital, Beppu 874-0838, shiozawa@port.kobe-u.ac.jp.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2018 Feb 09; Vol. 293 (6), pp. 1933-1943. Date of Electronic Publication: 2017 Nov 27.

Chronic Inflammation Disrupts Circadian Rhythms in Splenic CD4+ and CD8+ T Cells in Mice.

Autor: Hirose, Misa^1,2,3 (AUTHOR) misa.hirose@uni-luebeck.de, Leliavski, Alexei⁴ (AUTHOR), de Assis, Leonardo Vinícius Monteiro^1,2 (AUTHOR) l.skrum@uni-luebeck.de, Matveeva, Olga¹ (AUTHOR), Skrum, Ludmila^1,2 (AUTHOR), Solbach, Werner⁵ (AUTHOR) werner.solbach@uni-luebeck.de, Oster, Henrik^1,2 (AUTHOR) henrik.oster@uni-luebeck.de, Heyde, Isabel^1,2 (AUTHOR) henrik.oster@uni-luebeck.de

Publikováno v: Cells (2073-4409). Jan2024, Vol. 13 Issue 2, p151. 15p.