Zobrazeno 1 - 10 of 500 pro vyhledávání: '"Tsukimi Y"'
1
Akademický článek
Pharmacological evaluation of a novel corticotropin-releasing factor 1 receptor antagonist T-3047928 in stress-induced animal models in a comparison with alosetron.
Autor: Itomi Y; Inflammation DDU, Pharmacological Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Tanaka T; Inflammation DDU, Pharmacological Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Matsushita K; Inflammation DDU, Pharmacological Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Kawamura T; Inflammation DDU, Pharmacological Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Kojima T; Inflammation DDU, Pharmacological Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Aso K; Inflammation DDU, Pharmacological Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Matsumoto-Okano S; Inflammation DDU, Pharmacological Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Tsukimi Y; Inflammation DDU, Pharmacological Research Division, Takeda Pharmaceutical Company Limited, Kanagawa, Japan.
Publikováno v: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society [Neurogastroenterol Motil] 2020 May; Vol. 32 (5), pp. e13795. Date of Electronic Publication: 2020 Jan 22.
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2
Akademický článek
Effects of Stress Exposure to Pain Perception in Pre-Clinical Studies: Focus on the Nociceptin/Orphanin FQ–NOP Receptor System.
Autor: Pola, Pietro1 (AUTHOR) pietro.pola@unife.it, Frezza, Alessia1 (AUTHOR) alessia.frezza@unife.it, Gavioli, Elaine C.2 (AUTHOR) elaine.gavioli@ufrn.br, Calò, Girolamo3 (AUTHOR) girolamo.calo@unipd.it, Ruzza, Chiara1,4 (AUTHOR) chiara.ruzza@unife.it
Publikováno v: Brain Sciences (2076-3425). Sep2024, Vol. 14 Issue 9, p936. 23p.
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3
Akademický článek
Effects and sites of action of a M1 receptor positive allosteric modulator on colonic motility in rats and dogs compared with 5-HT 4 agonism and cholinesterase inhibition.
Autor: Tsukimi Y; Gastroenterology Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Pustovit RV; Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Vic., Australia., Harrington AM; Visceral Pain Research Group, Centre for Neuroscience, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.; Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.; Centre for Nutrition and Gastrointestinal Diseases, Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia., Garcia-Caraballo S; Visceral Pain Research Group, Centre for Neuroscience, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.; Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.; Centre for Nutrition and Gastrointestinal Diseases, Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia., Brierley SM; Visceral Pain Research Group, Centre for Neuroscience, College of Medicine and Public Health, Flinders University, Bedford Park, SA, Australia.; Hopwood Centre for Neurobiology, Lifelong Health Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia.; Centre for Nutrition and Gastrointestinal Diseases, Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia., Di Natale M; Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Vic., Australia., Molero JC; Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Vic., Australia., Furness JB; Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Vic., Australia.
Publikováno v: Neurogastroenterology and motility [Neurogastroenterol Motil] 2020 Aug; Vol. 32 (8), pp. e13866. Date of Electronic Publication: 2020 Apr 26.
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4
Akademický článek
The healing effects of moderate exercise on acetic acid-induced gastric ulcer in male rats.
Autor: Sofiabadi, Mohammad1, Bahadoran, Ensiyeh2, SamieeRad, Fatemeh3 fsamieerad@gmail.com, Talis, Abbas4
Publikováno v: Gastroenterology & Hepatology from Bed to Bench. Summer2024, Vol. 17 Issue 3, p313-319. 7p.
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5
Akademický článek
Muscarinic receptor 1 allosteric modulators stimulate colorectal emptying in dog, mouse and rat and resolve constipation.
Autor: Pustovit RV; Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Vic., Australia., Itomi Y; Gastroenterology Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Ringuet M; Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Vic., Australia., Diwakarla S; Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Vic., Australia., Chai XY; Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Vic., Australia., McQuade RM; Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Vic., Australia., Tsukimi Y; Gastroenterology Drug Discovery Unit, Takeda Pharmaceutical Company Limited, Kanagawa, Japan., Furness JB; Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.; Department of Anatomy & Neuroscience, University of Melbourne, Parkville, Vic., Australia.
Publikováno v: Neurogastroenterology and motility [Neurogastroenterol Motil] 2019 Nov; Vol. 31 (11), pp. e13692. Date of Electronic Publication: 2019 Aug 02.
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6
Akademický článek
Pharmacological effects of TAK-828F: an orally available RORγt inverse agonist, in mouse colitis model and human blood cells of inflammatory bowel disease.
Autor: Igaki K; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.; Axcelead Drug Discovery Partners, Inc., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Nakamura Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.; Pharmaceutical Sciences, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Tanaka M; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Mizuno S; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Yoshimatsu Y; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Komoike Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Uga K; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.; Axcelead Drug Discovery Partners, Inc., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Shibata A; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Imaichi H; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Takayuki S; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Ishimura Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Yamasaki M; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.; Axcelead Drug Discovery Partners, Inc., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Kanai T; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Tsukimi Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Tsuchimori N; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan. noboru.tsuchimori@takeda.com.
Publikováno v: Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2019 Jun; Vol. 68 (6), pp. 493-509. Date of Electronic Publication: 2019 Apr 10.
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7
Akademický článek
Pharmacological Evaluation of TAK-828F, a Novel Orally Available RORγt Inverse Agonist, on Murine Colitis Model.
Autor: Igaki K; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.; Axcelead Drug Discovery Partners, Inc., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Nakamura Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.; Pharmaceutical Sciences, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Komoike Y; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Uga K; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.; Axcelead Drug Discovery Partners, Inc., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Shibata A; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Ishimura Y; Drug safety Research Laboratories, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Yamasaki M; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan.; Axcelead Drug Discovery Partners, Inc., 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Tsukimi Y; Gastrointestinal Drug Discovery Unit, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan., Tsuchimori N; Pharmaceutical Research Division, Takeda Pharmaceutical Company, Limited, 26-1, Muraoka-Higashi 2-chome, Fujisawa, Kanagawa, 251-8555, Japan. noboru.tsuchimori@takeda.com.
Publikováno v: Inflammation [Inflammation] 2019 Feb; Vol. 42 (1), pp. 91-102.
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8
Akademický článek
Therapeutic potential of allosteric modulators for the treatment of gastrointestinal motility disorders.
Autor: Saito A; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia., Alvi S; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia., Valant C; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia., Christopoulos A; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia., Carbone SE; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia., Poole DP; Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, Victoria, Australia.
Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Jul; Vol. 181 (14), pp. 2232-2246. Date of Electronic Publication: 2023 Jan 18.
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9
Akademický článek
Pharmacological Inhibition of Toll-Like Receptor-4 Signaling by TAK242 Prevents and Induces Regression of Experimental Organ Fibrosis.
Autor: Bhattacharyya S; Northwestern Scleroderma Program, Feinberg School of Medicine, Chicago, IL, United States., Wang W; Northwestern Scleroderma Program, Feinberg School of Medicine, Chicago, IL, United States., Tamaki Z; Northwestern Scleroderma Program, Feinberg School of Medicine, Chicago, IL, United States., Shi B; Northwestern Scleroderma Program, Feinberg School of Medicine, Chicago, IL, United States., Yeldandi A; Northwestern Scleroderma Program, Feinberg School of Medicine, Chicago, IL, United States., Tsukimi Y; Takeda Pharmaceutical Company Limited, Tokyo, Japan., Yamasaki M; Takeda Pharmaceutical Company Limited, Tokyo, Japan., Varga J; Northwestern Scleroderma Program, Feinberg School of Medicine, Chicago, IL, United States.
Publikováno v: Frontiers in immunology [Front Immunol] 2018 Oct 23; Vol. 9, pp. 2434. Date of Electronic Publication: 2018 Oct 23 (Print Publication: 2018).
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10
Akademický článek
[Pharmacological characteristics and clinical efficacies of a novel potassium-competitive acid blocker, vonoprazan fumarate].
Autor: Matsukawa J; Gastroenterology Drug Discovery Unit, Takeda California, Inc., Inatomi N; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited., Nishida H; Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited., Tsukimi Y; Gastroenterology Drug Discovery Unit, Research, Takeda Pharmaceutical Company Limited.
Publikováno v: Nihon yakurigaku zasshi. Folia pharmacologica Japonica [Nihon Yakurigaku Zasshi] 2018; Vol. 152 (3), pp. 104-110.
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