Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Tsukimi Washizu"'
Publikováno v:
Veterinary dermatology. 6(4)
— Two Pugs and two Miniature Schnauzers with multiple pigmented epidermal nevi were investigated. The four dogs had pigmented cutaneous maculae and plaques. Histopathological evaluation showed papillated or digitated epidermal hyperplasia with hype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784bd4848bd7802ef53277a9cb5b67c3
https://pubmed.ncbi.nlm.nih.gov/34644894
https://pubmed.ncbi.nlm.nih.gov/34644894
Autor:
Sena Kurita, Kenichiro Ono, Tsukimi Washizu, Hiroyuki Tani, Makoto Bonkobara, Kyoichi Tamura, Ryo Miyamoto, Shiori Kuroki, Masato Kobayashi
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 40:101-104
Canine malignant melanoma (CMM) is a highly aggressive and fatal neoplasm. To identify potential therapeutic compounds and/or targets, 320 compounds were screened for their growth inhibitory activity in a CMM line (CMM-1) using a chemical library kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88be7f57f50cc90d7ec6c5efd06b193c
https://doi.org/10.1111/jvp.12336
https://doi.org/10.1111/jvp.12336
Autor:
Masato Kobayashi, Kyoichi Tamura, Tsukimi Washizu, Yukari Moriya, Yuji Uehara, Shiori Kuroki, Yu Tanaka, Makoto Bonkobara, Yukari Kozutumi, Kenichiro Ono
Publikováno v:
European Journal of Haematology. 95:524-531
Although imatinib has therapeutic activity for certain subsets of patients with mastocytosis, it is not always curative. Here, molecular mechanisms that confer imatinib resistance to neoplastic mast cells were investigated using an imatinib-sensitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df9c31366fa17fa93592ffc37afad51
https://doi.org/10.1111/ejh.12526
https://doi.org/10.1111/ejh.12526
Reconstruction of stratum corneum in organotypically cultured canine keratinocyte-derived CPEK cells
Autor:
Tsukimi Washizu, Nao Shinozaki, Toshiki Okumura, Yu Sasaki, Makoto Bonkobara, Shiori Kuroki, Kenichiro Ono, Keita Ito, Hiroko Yagihara, Eri Shiomi
Publikováno v:
Veterinary Research Communications. 35:433-437
The stratum corneum of epidermis is an essential barrier against the external environment and water loss. This study aimed to develop an organotypic culture model that targets the reconstruction of the stratum corneum using canine keratinocyte-derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7062e24d3d34ead00a817c3fbb130e
https://doi.org/10.1007/s11259-011-9477-7
https://doi.org/10.1007/s11259-011-9477-7
Autor:
Tsukimi Washizu, Osamu Yamada, Yasuhito Fujino, Hiroko Yagihara, Makoto Bonkobara, Mayu Isotani, Kenichiro Ono, Joshua L. Lachowicz, Kyoichi Tamura
Publikováno v:
British Journal of Haematology. 148:144-153
The purpose of the current study was to investigate the mutation status of KIT in feline mast cell tumours (MCTs) and to examine the effects of tyrosine kinase inhibition on the phosphorylation of mutant kit in vitro and in clinical cases of cats. Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43e97ddedb5b57af20dadc9e2e4b1e5d
https://doi.org/10.1111/j.1365-2141.2009.07926.x
https://doi.org/10.1111/j.1365-2141.2009.07926.x
Autor:
Tsukimi Washizu, M. Tominaga, Kenichiro Ono, Makoto Bonkobara, Michio Fujita, Mayu Isotani, T. Kobayashi, Yozo Fujino, S. Ochi, Kyoichi Tamura, N. Ishida, Hiroko Yagihara, R. Kato, Asuka Setoguchi
Publikováno v:
Journal of Veterinary Internal Medicine. 22:985-988
Background: Imatinib mesylate is a small molecule targeted at dysregulated protein-tyrosine kinase. Mutation of c-kit exon 11, which induces constitutive phosphorylation of KIT, is one of the mechanisms for the development or progression of mast cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0f483da8579108d4d08bb9dd2340ac
https://doi.org/10.1111/j.1939-1676.2008.00132.x
https://doi.org/10.1111/j.1939-1676.2008.00132.x
Autor:
Tsukimi Washizu, Kenichiro Ono, Mayu Isotani, Makoto Bonkobara, Hiroyoshi Arai, Kyoichi Tamura, Misato Yamada, Hiroko Yagihara
Publikováno v:
The Veterinary Journal. 175:126-129
To establish the basis for the use of dendritic cells (DC) in the treatment of canine melanoma, dogs were vaccinated using autologous DC pulsed with canine melanoma CMM2 cell lysate in the presence of keyhole limpet haemocyanin (KLH) in vitro (CMM2-K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::717e58c09e621a95a44f7810a61a598d
https://doi.org/10.1016/j.tvjl.2006.11.005
https://doi.org/10.1016/j.tvjl.2006.11.005
Autor:
Satoshi Tamahara, Tsukimi Washizu, Kenichiro Ono, Makoto Bonkobara, Mizuki Tomihari, Yukiho Asahara, Ken Sago, Akihiro Takei, Naoaki Matsuki
Publikováno v:
Journal of Veterinary Medical Science. 70:353-357
To investigate in vitro differentiation of canine adipose tissue-derived stromal cells (ATSCs) into neuronal cells, ATSCs from celiac adipose tissue in clinically healthy beagle dogs were treated with 100 muM dibutyryl cyclic adenosine monophosphate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbf3b2162e4de555f87ca84acddc862
https://doi.org/10.1292/jvms.70.353
https://doi.org/10.1292/jvms.70.353
Autor:
Tsukimi Washizu, Hiroko Yagihara, Makoto Bonkobara, Kenichiro Ono, Kyoichi Tamura, Mayu Isotani, Michiko Hikosaka
Publikováno v:
Veterinary Immunology and Immunopathology. 114:168-172
The gain-of-function mutations within c-kit, a protooncogene encoding KIT, induce constitutive ligand-independent kinase activation and are important for the pathogenesis of mast cell proliferative disease in humans as well as in dogs. Despite the cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73fc0c1ac24a5e9a1476d63ac286904d
https://doi.org/10.1016/j.vetimm.2006.07.004
https://doi.org/10.1016/j.vetimm.2006.07.004
Autor:
Kenichiro Ono, Y. Terada, Tsukimi Washizu, F. Hidaka, Kiyoshi Ariizumi, Osamu Yamada, Makoto Bonkobara, Hiroko Yagihara, S. Sugimoto
Publikováno v:
The Veterinary Journal. 172:141-146
The outermost layer of skin, the epidermis, is cornified epithelial tissue composed of keratinocytes. To maintain the structure and function of the epidermis, the regulation of proliferation, differentiation, and cornification of keratinocytes is cru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb428866b3c7f0554a00a95b32bb133
https://doi.org/10.1016/j.tvjl.2005.04.009
https://doi.org/10.1016/j.tvjl.2005.04.009