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of 7
pro vyhledávání: '"Tsukimi Iida"'
Thermodynamic stability of human lipocalin-type prostaglandin D synthase under various pH conditions
Autor:
Tsukimi Iida, Masatoshi Nakatsuji, Yoshiaki Teraoka, Yuji Goto, Takaki Yamamura, Takashi Inui
Publikováno v:
The Journal of Biochemistry.
Lipocalin-type prostaglandin D synthase (L-PGDS) binds various hydrophobic small molecules. Since we aim to use human L-PGDS as a carrier in a drug delivery system (DDS) for poorly water-soluble drugs, quality control of the protein is indispensable.
Autor:
Maki Mochizuki, Tadayasu Ohkubo, Susumu Uchiyama, Tsukimi Iida, Shigenori Nishimura, Akiyoshi Tanaka, Yoshihiro Urade, Takashi Inui
Publikováno v:
FEBS Journal. 275:233-241
Lipocalin-type prostaglandin (PG) D synthase (L-PGDS) is a dual-functioning protein in the lipocalin family, acting as a PGD(2)-synthesizing enzyme and as an extracellular transporter for small lipophilic molecules. We earlier reported that denaturan
Autor:
Tsukimi Iida, Yasuo Noda, Shin-ichi Segawa, Yuya Miyamoto, Akiyoshi Tanaka, Keisuke Yamaguchi, Takashi Inui, Shigenori Nishimura
Publikováno v:
Journal of biochemistry. 151(3)
We previously reported that the thermal unfolding of mouse lipocalin-type prostaglandin D synthase (L-PGDS) is a completely reversible process under acidic conditions and follows a three-state pathway, including an intermediate state (I) between nati
Autor:
Tsukimi, Iida, Shigenori, Nishimura, Maki, Mochizuki, Susumu, Uchiyama, Tadayasu, Ohkubo, Yoshihiro, Urade, Akiyoshi, Tanaka, Takashi, Inui
Publikováno v:
The FEBS journal. 275(2)
Lipocalin-type prostaglandin (PG) D synthase (L-PGDS) is a dual-functioning protein in the lipocalin family, acting as a PGD(2)-synthesizing enzyme and as an extracellular transporter for small lipophilic molecules. We earlier reported that denaturan
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 823(2)
Membrane proteins were obtained from the mitochondrial fraction of HL-60 cells by solubilization with octyl glucoside and bound to heparin-gels. Bound proteins were successively eluted with solutions containing increasing concentrations of Mg(2+) in
Autor:
Satoshi Kume, Tsukimi Iida, Takashi Inui, Shigenori Nishimura, Kaoru Saruwatari, Harumi Fukuda
Publikováno v:
Seibutsu Butsuri. 50:S95
Autor:
Iida, Tsukimi1,2 (AUTHOR), Nakatsuji, Masatoshi1 (AUTHOR), Teraoka, Yoshiaki1 (AUTHOR), Goto, Yuji3 (AUTHOR), Yamamura, Takaki1 (AUTHOR), Inui, Takashi1 (AUTHOR) inuit@omu.ac.jp
Publikováno v:
Journal of Biochemistry. Jul2023, Vol. 174 Issue 1, p21-31. 11p.