Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Tsukasa Shimauchi"'
Publikováno v:
JA Clinical Reports, Vol 7, Iss 1, Pp 1-5 (2021)
Abstract Background Neurotoxicity caused by a local anesthetic after regional anesthesia is a rare but serious problem for anesthesiologists. It is difficult to diagnose neurotoxicity from anesthetics because of the large number of possible diagnoses
Externí odkaz:
https://doaj.org/article/97d27c326e7b4948947a9ed6fb37371f
Autor:
Tsukasa Shimauchi, Takuro Numaga-Tomita, Yuri Kato, Hiroyuki Morimoto, Kosuke Sakata, Ryosuke Matsukane, Akiyuki Nishimura, Kazuhiro Nishiyama, Atsushi Shibuta, Yutoku Horiuchi, Hitoshi Kurose, Sang Geon Kim, Yasuteru Urano, Takashi Ohshima, Motohiro Nishida
Publikováno v:
Cells, Vol 11, Iss 13, p 2041 (2022)
Retarded revascularization after progressive occlusion of large conductance arteries is a major cause of bad prognosis for peripheral artery disease (PAD). However, pharmacological treatment for PAD is still limited. We previously reported that suppr
Externí odkaz:
https://doaj.org/article/e89d2112d64a412badfa2e0abc81ba01
Autor:
Sayaka Oda, Takuro Numaga-Tomita, Naoyuki Kitajima, Takashi Toyama, Eri Harada, Tsukasa Shimauchi, Akiyuki Nishimura, Tatsuya Ishikawa, Yoshito Kumagai, Lutz Birnbaumer, Motohiro Nishida
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Excess production of reactive oxygen species (ROS) caused by hyperglycemia is a major risk factor for heart failure. We previously reported that transient receptor potential canonical 3 (TRPC3) channel mediates pressure overload-induced mala
Externí odkaz:
https://doaj.org/article/1d2ac9be588947d783316c98deccb3ba
Publikováno v:
JA Clinical Reports, Vol 4, Iss 1, Pp 1-3 (2018)
Abstract Background Arginine vasopressin has been used for the management of refractory vasodilatory shock. However, it is still unclear whether arginine vasopressin is useful for hypotension in patients with spinal cord injury. Case description A 78
Externí odkaz:
https://doaj.org/article/cf5e06a5d04e43b49c6ff5695f46d101
Autor:
Sarah-Eve Lemay, Charifa Awada, Tsukasa Shimauchi, Wen-Hui Wu, Sébastien Bonnet, Steeve Provencher, Olivier Boucherat
Publikováno v:
Cells, Vol 10, Iss 6, p 1473 (2021)
Pulmonary arterial hypertension is a debilitating chronic disorder marked by the progressive obliteration of the pre-capillary arterioles. This imposes a pressure overload on the right ventricle (RV) pushing the latter to undergo structural and mecha
Externí odkaz:
https://doaj.org/article/a6ee1f26504042c7980de5283f7c61c0
Autor:
Takuro Numaga-Tomita, Sayaka Oda, Tsukasa Shimauchi, Akiyuki Nishimura, Supachoke Mangmool, Motohiro Nishida
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 4 (2017)
Cardiac stiffness, caused by interstitial fibrosis due to deposition of extracellular matrix proteins, is thought as a major clinical outcome of heart failure with preserved ejection fraction (HFpEF). Canonical transient receptor potential (TRPC) sub
Externí odkaz:
https://doaj.org/article/e2b4e88afcb9439288638411a1eb56cf
Autor:
Tsukasa Shimauchi, Olivier Boucherat, Tetsuro Yokokawa, Yann Grobs, WenHui Wu, Mark Orcholski, Sandra Martineau, Junichi Omura, Eve Tremblay, Kana Shimauchi, Valérie Nadeau, Sandra Breuils-Bonnet, Roxane Paulin, François Potus, Steeve Provencher, Sébastien Bonnet
Publikováno v:
JACC: Basic to Translational Science. 7:384-403
The authors show that increased poly(adenosine diphosphate-ribose) polymerase 1 (PARP1) and pyruvate kinase muscle isozyme 2 (PKM2) expression is a common feature of a decompensated right ventricle in patients with pulmonary arterial hypertension and
Autor:
Junichi Omura, Sandra Breuils-Bonnet, Eve Tremblay, Alice Bourgeois, Steeve Provencher, Yann Grobs, Tsukasa Shimauchi, Geraldine Vitry, Wen-Hui Wu, Victoria Toro, Mark Orcholski, Roxane Paulin, Sandra Martineau, Valérie Nadeau, Sébastien Bonnet, Pasquale Ferraro, Charlotte Romanet, François Potus, Olivier Boucherat
Publikováno v:
Thorax. 77:247-258
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterised by exuberant tissue remodelling and associated with high unmet medical needs. Outcomes are even worse when IPF results in secondary pulmonary hypertension (PH). Imp
Autor:
Sandra Breuils-Bonnet, Allan Lawrie, Stephen L. Archer, Eve Tremblay, Tsukasa Shimauchi, François Potus, David G. Kiely, Wen-Hui Wu, Jianhui Lin, Olivier Boucherat, Valérie Nadeau, Sébastien Bonnet, Kassandra Gagnon, Sandra Martineau, Karima Habbout, Hamza Zafar, Roxane Paulin, Steeve Provencher, Junichi Omura, Jean Perron, Florence Mazoyer
Publikováno v:
Circulation. 142:1464-1484
Background: Right ventricular (RV) function is the major determinant for both functional capacity and survival in patients with pulmonary arterial hypertension (PAH). Despite the recognized clinical importance of preserving RV function, the subcellul
Autor:
Duncan J. Stewart, L. Christian Napp, Jason G.E. Zelt, Volker Rudolph, Torben Schubert, Ekaterina Legchenko, Georg Hansmann, Anna Klinke, Marion Müller, Tsukasa Shimauchi, Alexander M.K. Rothman, Sébastien Bonnet
Publikováno v:
Cardiovasc Diagn Ther
Therapeutic options for right ventricular (RV) dysfunction and failure are strongly limited. Right heart failure (RHF) has been mostly addressed in the context of pulmonary arterial hypertension (PAH), where it is not possible to discern pulmonary va