Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Tsukasa Kitahashi"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Synovial mesenchymal stem cells (MSCs) injected into the knee promote meniscus regeneration in several animal models; however, the mode of action is unknown. Our purpose was to identify the molecules responsible for this meniscus regeneratio
Externí odkaz:
https://doaj.org/article/0d010c16320f4a978c50570e03b05abb
Autor:
Yoshiteru Kamiyama, Yoichi Naritomi, Yuu Moriya, Syunsuke Yamamoto, Tsukasa Kitahashi, Toshihiko Maekawa, Masahiro Yahata, Takeshi Hanada, Asako Uchiyama, Akari Noumaru, Yoshiyuki Koga, Tomoaki Higuchi, Masahiko Ito, Hiroyuki Komatsu, Sosuke Miyoshi, Sadaaki Kimura, Nobuhiro Umeda, Eriko Fujita, Naoko Tanaka, Taku Sugita, Satoru Takayama, Akihiko Kurogi, Satoshi Yasuda, Yoji Sato
Publikováno v:
Regenerative Therapy, Vol 18, Iss , Pp 202-216 (2021)
Information on the biodistribution (BD) of cell therapy products (CTPs) is essential for prediction and assessment of their efficacy and toxicity profiles in non-clinical and clinical studies. To conduct BD studies, it is necessary to understand regu
Externí odkaz:
https://doaj.org/article/61bffe5d05ba4298956d71476d7932c0
Autor:
Soichiro Takamiya, Masahito Kawabori, Tsukasa Kitahashi, Kentaro Nakamura, Yuki Mizuno, Hironobu Yasui, Yuji Kuge, Aki Tanimori, Yasuyuki Takamatsu, Kohei Yuyama, Hideo Shichinohe, Miki Fujimura
Publikováno v:
Stem Cells International, Vol 2022 (2022)
Background. Due to the lack of effective therapies, stem cell transplantation is an anticipated treatment for chronic intracerebral hemorrhage (ICH), and higher cell survival and engraftment are considered to be the key for recovery. Mesenchymal stro
Externí odkaz:
https://doaj.org/article/5663bf5c969941958d31f88679ccb2cd
Publikováno v:
Cell Transplantation, Vol 27 (2018)
Cell therapies using adipose-derived stem cells (ADSCs) have been used to treat inflammatory bowel disease (IBD) in human and dog. We previously reported the CellSaic technique, which uses a recombinant scaffold to enhance the efficacy of cell therap
Externí odkaz:
https://doaj.org/article/29c7f18de5b1465eb5770274cb2ca686
Autor:
Toshio Imai, Tsukasa Kitahashi
Publikováno v:
Journal of Applied Toxicology. 34:57-65
Acrylamide (AA) is known to induce tumors in various organs/tissues in rats and mice. Epidemiological studies of oral exposure have generated controversial results but mortality studies of people who work with AA have indicated increased rates of pan
Autor:
Yoshihiro Nomura, Kenji Shimizu, Akika Sakamoto, Shoko Ikawa, Yasushi Nakamura, Shuji Sasabe, Kenji Sato, Tsukasa Kitahashi, Toshifumi Tsujiuchi, Eun Young Park, Masahiro Tsutsumi
Publikováno v:
Journal of Agricultural and Food Chemistry. 60:940-945
A water extract of shark cartilage was fractionated into acidic and basic fractions by preparative isoelectric focusing on the basis of the amphoteric nature of samples. The acidic fraction was further fractionated into ethanol-soluble and -precipita
Autor:
Toshio Imai, Masaaki Iigo, Nobuo Takasuka, Keiji Wakabayashi, Mami Takahashi, Tsukasa Kitahashi, Naoki Yoshimi, Takashi Sugimura, Yusaku Hori
Publikováno v:
Cancer Letters. 275:150-157
Tumor promotion potential of diacylglycerol (DAG)-rich edible oil was examined using a two-stage mouse skin carcinogenesis model initiated with 7,12-dimethylbenz[a]anthracene (DMBA). Topical treatment with 75 mg DAG oil once a day for 5 days/week for
Autor:
Yuko Nakayama, Yasushi Nakamura, Kenji Sato, Meiko Yokoyama, Akari Kominami, Masashi Kuwahata, Sonoko Yoshimoto, Chia-Cheng Chang, James E. Trosko, Asuka Kubo, Yasuhiro Kido, Minami Kageyama, Shinpei Watanabe, Yoshiyuki Tsujimoto, Yukiko Kobayashi, Brad L. Upham, Tsukasa Kitahashi, Eun Young Park
Publikováno v:
International Journal of Cancer. 124:2512-2519
The introduction of the tumorigenic v-Ha-ras oncogene-transformed rat liver epithelial cells (WBras), which is deficient in gap junctional intercellular communication (GJIC), into F344 rats, induces significant formation of hepatocellular tumors. GJI
Autor:
Hidetaka Sato, Michihiro Mutoh, Masao Naka, Rikako Ishigamori, Yoshihisa Kamanaka, Keiji Wakabayashi, Mami Takahashi, Takayuki Maruyama, Tsukasa Kitahashi, Takashi Sugimura, Masami Komiya
Publikováno v:
Carcinogenesis. 29:1608-1613
Elevated protein expression of inducible nitric oxide synthase (iNOS) has been observed in human pancreatic cancers and therefore, iNOS may play important roles in pancreatic carcinogenesis. This was examined in the present study, using an experiment
Autor:
Nobuo Takasuka, Yutaka Yamada, Mami Takahashi, Tsukasa Kitahashi, Yoichi Oghiso, Masahiro Tsutsumi, Katsumi Imaida, Takashi Sugimura, Keiji Wakabayashi, Masanao Yokohira
Publikováno v:
Cancer Science. 99:241-245
Epidermal growth factor receptor (EGFR) gene alterations have been found in human lung cancers. However, there is no information on the factors inducing EGFR mutations. In rodents, K-ras mutations are frequently found in many lung carcinogenesis mode