Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Tsukasa, Sakaida"'
Publikováno v:
Neuro-Oncology Advances. 4:iii22-iii22
Background Leptomeningeal carcinomatosis (LMC) is the most difficult condition to treat brain metastases (BM), and the presence or absence of malignant cells in the cerebrospinal fluid (CSF) is important in determining treatment strategies. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f43369039aa401acda99f7981e9df507
https://doi.org/10.1093/noajnl/vdac167.086
https://doi.org/10.1093/noajnl/vdac167.086
Autor:
Yonehiro Kanemura, Masayuki Kanamori, Fumi Higuchi, Yoshitaka Narita, Ken ichiro Matsuda, Yukitomo Ishi, Shunsaku Takayanagi, Kuniaki Saito, Takashi Komori, Ryunosuke Machida, Yohei Miyake, Takashi Sasayama, Ryo Nishikawa, Yasuhiko Hattori, Ryusuke Hatae, Koichi Ichimura, Teiji Tominaga, Masahiro Mizoguchi, Ryohei Otani, Hiroyoshi Suzuki, Yoshiko Okita, Yuko Matsushita, Mitsutoshi Nakada, Shota Tanaka, Yukihiko Sonoda, Hikaru Sasaki, Masahiro Nonaka, Nobuhiro Hata, Motoo Nagane, Tomoko Shofuda, Haruhiko Kishima, Eriel Sandika Pareira, Takehiro Uda, Yasuji Miyakita, Taishi Nakamura, Aya Kuchiba, Shigeru Yamaguchi, Kazuhiko Kurozumi, Ryuta Saito, Keiichi Kobayashi, Junya Fukai, Hideyuki Arita, Kaoru Tamura, Tsukasa Sakaida, Makoto Shibuya, Toshihiko Iuchi, Makoto Ohno, Daisuke Sakamoto, Kai Yamasaki, Sho Tamai, Kazuhiro Tanaka
Publikováno v:
Acta Neuropathologica Communications
TERT promoter mutations are commonly associated with 1p/19q codeletion in IDH-mutated gliomas. However, whether these mutations have an impact on patient survival independent of 1p/19q codeletion is unknown. In this study, we investigated the impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d98a03627094d2c8a28e4361ecb344
https://pubmed.ncbi.nlm.nih.gov/33228806
https://pubmed.ncbi.nlm.nih.gov/33228806
Autor:
Toshihiko Iuchi, Masato Syngyoji, Hironori Ashinuma, Satoko Mizuno, Yuzo Hasegawa, Taiki Setoguchi, Junji Hosono, Tsukasa Sakaida
Publikováno v:
Neuro-oncology Advances
Background: Because of the invasive nature of small cell lung cancer (SCLC), the effectiveness of local therapy for brain metastases (BM) from SCLC had been limited. In this article, we retrospectively evaluated the efficacy of chemotherapy against n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41cb6b34722533bf5551074e5117ba17
http://europepmc.org/articles/PMC8664637
http://europepmc.org/articles/PMC8664637
Publikováno v:
Carcinogenesis. 29:1878-1884
p53-upregulated modulator of apoptosis (PUMA) plays an essential role in p53-dependent apoptosis following DNA damage. PUMA also mediates apoptosis independent of p53. In this study, we investigated the role and mechanism of PUMA induction in respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7480f2dfd2d78127b3873179589022
https://doi.org/10.1093/carcin/bgn150
https://doi.org/10.1093/carcin/bgn150
Autor:
Ian F. Pollack, Andrea Gambotto, Wendy Fellows-Mayle, Hidemitsu Sato, Hideho Okada, Jill E. Dusak, Manabu Hatano, Naruo Kuwashima, Simon C. Watkins, Tsukasa Sakaida, Glenn D. Papworth
Publikováno v:
Cancer Gene Therapy. 12:757-768
We have created a novel cellular vehicle for gene therapy of malignant gliomas by transfection of murine bone marrow stroma cells (MSCs) with a cDNA encoding epidermal growth factor receptor (EGFR). These cells (EGFR-MSCs) demonstrate enhanced migrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5382363a5389b669b50f5f49a686d9c1
https://doi.org/10.1038/sj.cgt.7700827
https://doi.org/10.1038/sj.cgt.7700827
Publikováno v:
Molecular cancer therapeutics. 6(12 Pt 1)
Head and neck squamous cell carcinoma (HNSCC) ranks the eighth most common cancer worldwide. The patients often present with advanced disease, which responds poorly to chemoradiation therapy. PUMA is a BH3-only Bcl-2 family protein and a p53 target t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e6fa257d6fcb0d1093aea55f3a1e0b
https://pubmed.ncbi.nlm.nih.gov/18089712
https://pubmed.ncbi.nlm.nih.gov/18089712
Autor:
Yuichiro Nagai, Hiroshi Ishikura, Akira Yamaura, Tsukasa Sakaida, Yasuo Iwadate, Masaki Takiguchi, Takaki Hiwasa
Publikováno v:
Cancer research. 64(7)
The biological features of gliomas, which are characterized by highly heterogeneous biological aggressiveness even in the same histological category, would be precisely described by global gene expression data at the protein level. We investigated wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afed717e83b8f6b428d09472fd1df210
https://pubmed.ncbi.nlm.nih.gov/15059904
https://pubmed.ncbi.nlm.nih.gov/15059904
Autor:
Takenori Ochiai, Takaki Hiwasa, Tsukasa Sakaida, Namiko Kuroiwa, Motoo Kitagawa, Masaki Takiguchi, Hideaki Shimada
Publikováno v:
FEBS letters. 552(2-3)
We have developed a method that we call 'drug-sensitivity pattern analysis', or DSPA, for analysis of protein function. Cells are transfected with cDNA of the test molecule, followed by analysis of the sensitivity of the transfected cells to multiple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f4effb9b80be7eb92f8754c9221cc4c
https://pubmed.ncbi.nlm.nih.gov/14527683
https://pubmed.ncbi.nlm.nih.gov/14527683
Autor:
Akira Yamaura, Tsukasa Sakaida, Asao Noda, Masaki Takiguchi, Masae Uehara, Yasuo Iwadate, Sachi Yamaji, Takaki Hiwasa
Publikováno v:
International Journal of Oncology.
Apoptotic cell death is frequently suppressed by NF-kappaB transcription factor. We examined the effects of NF-kappaB on the sensitivity to anti-cancer drugs by using two NF-kappaB-inhibitory molecules, IkappaBalpha-super-repressor (IkappaBalpha-SR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0206e966059891a0c2fc7ded794984e4
https://doi.org/10.3892/ijo.23.4.1071
https://doi.org/10.3892/ijo.23.4.1071
Autor:
Tsukasa, Sakaida, Yasuo, Iwadate, Sachi, Yamaji, Masae, Uehara, Asao, Noda, Masaki, Takiguchi, Akira, Yamaura, Takaki, Hiwasa
Publikováno v:
International journal of oncology. 23(4)
Apoptotic cell death is frequently suppressed by NF-kappaB transcription factor. We examined the effects of NF-kappaB on the sensitivity to anti-cancer drugs by using two NF-kappaB-inhibitory molecules, IkappaBalpha-super-repressor (IkappaBalpha-SR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::264f60869611961dbab2beb53ffccadb
https://pubmed.ncbi.nlm.nih.gov/12963987
https://pubmed.ncbi.nlm.nih.gov/12963987