Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Tsukasa, Oda"'
Publikováno v:
Cell Proliferation.
Autor:
Tetsuhiro Kasamatsu, Maaya Awata-Shiraiwa, Rei Ishihara, Yuki Murakami, Yuta Masuda, Nanami Gotoh, Tsukasa Oda, Akihiko Yokohama, Ikuko Matsumura, Hiroshi Handa, Norifumi Tsukamoto, Hirokazu Murakami, Takayuki Saitoh
Cellular senescence refers to a pause in the cell cycle, usually in response to internal and/or external stress, including telomere dysfunction, abnormal cellular growth, and DNA damage. Several chemotherapeutic drugs, such as melphalan (MEL) and dox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b22ab39c17f040e6f75602f9bd14e57
https://doi.org/10.21203/rs.3.rs-2058604/v1
https://doi.org/10.21203/rs.3.rs-2058604/v1
Autor:
Nanami Gotoh, Keiko Okuda, Hiroshi Handa, Takayuki Saitoh, Takayuki Yamashita, Ruri Nakamura, Hirokazu Murakami, Tsukasa Oda, Tetsuhiro Kasamatsu
Publikováno v:
Cancer Gene Therapy. 29:225-240
Major histocompatibility complex class II (MHC II) is important for the adaptive immune response because MHC II presents processed antigens to a cluster of differentiation 4 (CD4)-positive T-cells. Conventional doses of chemotherapeutic agents induce
Autor:
Rei Ishihara, Tsukasa Oda, Yuki Murakami, Ikuko Matsumura, Saki Watanabe, Yuta Asao, Yuta Masuda, Nanami Gotoh, Tetsuhiro Kasamatsu, Hisashi Takei, Nobuhiko Kobayashi, Nobuo Sasaki, Takayuki Saitoh, Hirokazu Murakami, Hiroshi Handa
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 3
Pages: 2216
Volume 24
Issue 3
Pages: 2216
Tissue inhibitors of metalloproteinases (TIMPs) are endogenous matrix metalloproteinase inhibitors. TIMP1 is produced by cancer cells and has pleiotropic activities. However, its role and source in multiple myeloma (MM) are unclear. Here, we evaluate
Autor:
Yuki Murakami, Kei Kimura-Masuda, Tsukasa Oda, Ikuko Matsumura, Yuta Masuda, Rei Ishihara, Saki Watanabe, Yuko Kuroda, Tetsuhiro Kasamatsu, Nanami Gotoh, Hisashi Takei, Nobuhiko Kobayashi, Takayuki Saitoh, Hirokazu Murakami, Hiroshi Handa
Publikováno v:
Genes; Volume 14; Issue 1; Pages: 100
MicroRNAs (miRNAs and miRs) are small (19–25 base pairs) non-coding RNAs with the ability to modulate gene expression. Previously, we showed that the miR-34 family is downregulated in multiple myeloma (MM) as the cancer progressed. In this study, w
Autor:
Takayuki Saitoh, Tsukasa Oda
Publikováno v:
Cancers
Cancers, Vol 13, Iss 504, p 504 (2021)
Cancers, Vol 13, Iss 504, p 504 (2021)
Simple Summary Multiple myeloma (MM) is a plasma cell malignancy. Novel therapies have improved outcomes in MM patients; however, MM still remains incurable. MM cells present genomic instability, whose molecular basis is not fully understood. Recentl
Autor:
Tetsuhiro, Kasamatsu, Nao, Hashimoto, Nao, Sakaya, Maaya, Awata-Shiraiwa, Rei, Ishihara, Yuki, Murakami, Yuta, Masuda, Nanami, Gotoh, Kazue, Nagai, Tsukasa, Oda, Akihiko, Yokohama, Takayuki, Saitoh, Hiroshi, Handa, Norifumi, Tsukamoto, Kunihiko, Hayashi, Hirokazu, Murakami
Publikováno v:
Clinical and experimental medicine. 21(2)
Single-nucleotide polymorphisms (SNPs) of the IDO1 and IDO2 genes have been associated with some diseases. Here, we investigated the association of IDO1 and IDO2 SNPs with the susceptibility to multiple myeloma (MM) and their relationships with MM cl
Autor:
Yuta Masuda, Hirokazu Murakami, Tsukasa Oda, Rei Ishihara, Yuki Murakami, Kenichi Tahara, Hisashi Takei, Yuko Kuroda, Tetsuhiro Kasamatsu, Takayuki Saitoh, Kei Kimura-Masuda, Saki Watanabe, Hiroshi Handa, Kazuki Honma, Nobuhiko Kobayashi
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 19
International Journal of Molecular Sciences, Vol 21, Iss 7121, p 7121 (2020)
Volume 21
Issue 19
International Journal of Molecular Sciences, Vol 21, Iss 7121, p 7121 (2020)
Long noncoding RNAs (lncRNAs) are deregulated in human cancers and are associated with disease progression. Plasmacytoma Variant Translocation 1 (PVT1), a lncRNA, is located adjacent to the gene MYC, which has been linked to multiple myeloma (MM). PV
Autor:
Nobuhiko Kobayashi, Akihiko Yokohama, Makiko Takizawa, Hirokazu Murakami, Takayuki Saitoh, Kei Kimura-Masuda, Rei Ishihara, Yuki Murakami, Yuko Kuroda, Hiroaki Shimizu, Hisashi Takei, Tsukasa Oda, Takuma Ishizaki, Hiroshi Handa, Kazuki Honma, Norifumi Tsukamoto
Publikováno v:
Cancers, Vol 12, Iss 2, p 363 (2020)
Cancers
Volume 12
Issue 2
Cancers
Volume 12
Issue 2
Acute myeloid leukemia (AML) with granulocytic sarcoma (GS) is characterized by poor prognosis
however, its underlying mechanism is unclear. Bone marrow samples from 64 AML patients (9 with GS and 55 without GS) together with AML cell lines PL21
however, its underlying mechanism is unclear. Bone marrow samples from 64 AML patients (9 with GS and 55 without GS) together with AML cell lines PL21
Autor:
Norifumi Tsukamoto, Hiroshi Handa, Tsukasa Oda, Takayuki Saitoh, Alkebsi Lobna, Akihiko Yokohama, Hiroaki Shimizu, Toru Sakura, Hirokazu Murakami, Nanami Gotoh, Takumi Hoshino, Tetsuhiro Kasamatsu, Noriyuki Takahashi, Yusuke Minato, Makiko Takizawa
Publikováno v:
International Journal of Hematology. 108:246-253
Recent studies have shown that tumors of relapsed acute myeloid leukemia (AML) present additional genetic mutations compared to the primary tumors. The base excision repair (BER) pathway corrects oxidatively damaged mutagenic bases and plays an impor