Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Tsui-Ting Ching"'
Autor:
Wen-Chi Shen, Chiou-Hwa Yuh, Yu-Ting Lu, Yen-Hung Lin, Tsui-Ting Ching, Chao-Yung Wang, Horng-Dar Wang
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 124 (2023)
Deregulation of redox homeostasis is often associated with an accelerated aging process. Ribose-5-phosphate isomerase A (RPIA) mediates redox homeostasis in the pentose phosphate pathway (PPP). Our previous study demonstrated that Rpi knockdown boost
Externí odkaz:
https://doaj.org/article/8c0ecf7a0d92447a819df5e7945118ed
Autor:
Zhi-Han Lin, Shun-Ya Chang, Wen-Chi Shen, Yen-Hung Lin, Chiu-Lun Shen, Sin-Bo Liao, Yu-Chun Liu, Chang-Shi Chen, Tsui-Ting Ching, Horng-Dar Wang
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 612 (2022)
Altered metabolism is a hallmark of aging. The tricarboxylic acid cycle (TCA cycle) is an essential metabolic pathway and plays an important role in lifespan regulation. Supplementation of α-ketoglutarate, a metabolite converted by isocitrate dehydr
Externí odkaz:
https://doaj.org/article/44fc572a86f34d51864d44ad2ca57657
Autor:
Feng-Yung Wang, Tsui-Ting Ching
Publikováno v:
Bio-Protocol, Vol 11, Iss 16 (2021)
The nematode Caenorhabditis elegans has emerged as a popular model system for studying the regulation of lipid metabolism. Therefore, it is critical to develop a method for determining fat storage in individual worms. Oil Red O (ORO) staining has bee
Externí odkaz:
https://doaj.org/article/20454c7caab54828bea930a07d9ff36d
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241455 (2020)
S-adenosyl methionine synthetase (SAMS) catalyzes the biosynthesis of S-adenosyl methionine (SAM), which serves as a universal methyl group donor for numerous biochemical reactions. Previous studies have clearly demonstrated that SAMS-1, a C. elegans
Externí odkaz:
https://doaj.org/article/f2602c6aeb464e18b0cd2cfa6f8dc2d7
Autor:
Yan-Xi Chen, Phuong Thu Nguyen Le, Tsai-Teng Tzeng, Thu-Ha Tran, Anh Thuc Nguyen, Irene Han-Juo Cheng, Chi-Ying F. Huang, Young-Ji Shiao, Tsui-Ting Ching
Publikováno v:
Nutrients, Vol 13, Iss 12, p 4317 (2021)
Declines in physiological functions are the predominant risk factors for age-related diseases, such as cancers and neurodegenerative diseases. Therefore, delaying the aging process is believed to be beneficial in preventing the onset of age-related d
Externí odkaz:
https://doaj.org/article/d04a4e152043449ab597d981a23f1e5a
Autor:
Chiao-Yin Lim, Huan-Ting Lin, Caroline Kumsta, Tzu-Chiao Lu, Feng-Yung Wang, Yun-Hsuan Kang, Malene Hansen, Tsui-Ting Ching, Ao-Lin Hsu
Publikováno v:
Autophagy
Dietary restriction (DR) is known to promote autophagy to exert its longevity effect. While SAMS-1 (S-adenosyl methionine synthetase-1) has been shown to be a key mediator of the DR response, little is known about the roles of S-adenosyl methionine (
Supplementary Table 1 from Genome-wide Hypomethylation in Human Glioblastomas Associated with Specific Copy Number Alteration, Methylenetetrahydrofolate Reductase Allele Status, and Increased Proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405b6348eccddd0c25c7237ef6a68064
https://doi.org/10.1158/0008-5472.22364903.v1
https://doi.org/10.1158/0008-5472.22364903.v1
Genome-wide reduction in 5-methylcytosine is an epigenetic hallmark of human tumorigenesis. Experimentally induced hypomethylation in mice promotes genomic instability and is sufficient to initiate tumorigenesis. Here, we report that global hypomethy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2088c61abeb75e4f643ac5a65162db99
https://doi.org/10.1158/0008-5472.c.6494429.v1
https://doi.org/10.1158/0008-5472.c.6494429.v1
Supplementary Figure 1 from Genome-wide Hypomethylation in Human Glioblastomas Associated with Specific Copy Number Alteration, Methylenetetrahydrofolate Reductase Allele Status, and Increased Proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42d189deec0fd5668731dbb839bbefee
https://doi.org/10.1158/0008-5472.22364912
https://doi.org/10.1158/0008-5472.22364912
Supplementary Methods from Genome-wide Hypomethylation in Human Glioblastomas Associated with Specific Copy Number Alteration, Methylenetetrahydrofolate Reductase Allele Status, and Increased Proliferation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abbdead5e3b6c9effe7de9ff637e6f24
https://doi.org/10.1158/0008-5472.22364909.v1
https://doi.org/10.1158/0008-5472.22364909.v1