Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tsui Han Loo"'
Autor:
Tsui Han Loo, Xiaoqian Ye, Ruth Jinfen Chai, Mitsuteru Ito, Gisèle Bonne, Anne C Ferguson-Smith, Colin L Stewart
Publikováno v:
eLife, Vol 8 (2019)
Here we show that a major muscle specific isoform of the murine LINC complex protein SUN1 is required for efficient muscle regeneration. The nucleoplasmic domain of the isoform specifically binds to and inhibits Drosha, a key component of the micropr
Externí odkaz:
https://doaj.org/article/91a0a0b2e6f24b3b9e111f25c07c8652
Autor:
Ming-Yi Chou, Meng-Chuen Hu, Pin-Yu Chen, Chi-Lin Hsu, Ting-Yu Lin, Mao-Jia Tan, Chih-Yu Lee, Meng-Fai Kuo, Pei-Hsin Huang, Vin-Cent Wu, Shih-Hung Yang, Pi-Chuan Fan, Hsin-Yi Huang, Schahram Akbarian, Tsui-Han Loo, Colin L Stewart, Hsiang-Po Huang, Susan Shur-Fen Gau, Hsien-Sung Huang
Publikováno v:
Human Molecular Genetics. 31:3161-3180
RTL1/PEG11, which has been associated with anxiety disorders, is a retrotransposon-derived imprinted gene in the placenta. However, imprinting patterns and functions of RTL1 in the brain have not been well-investigated. We found Rtl1 was paternally,
Publikováno v:
Current opinion in geneticsdevelopment. 67
The regulation of genomic function is in part mediated through the physical organization and architecture of the nucleus. Disruption to nuclear organization and architecture is increasingly being recognized by its contribution to many diseases. The L
Autor:
Anne C. Ferguson-Smith, Gisèle Bonne, Colin L. Stewart, Mitsuteru Ito, Ruth Jinfen Chai, Xiaoqian Ye, Tsui Han Loo
Publikováno v:
eLife
eLife, 2019, 8, ⟨10.7554/eLife.49485⟩
eLife, eLife Sciences Publication, 2019, 8, ⟨10.7554/eLife.49485⟩
eLife, Vol 8 (2019)
eLife, 2019, 8, ⟨10.7554/eLife.49485⟩
eLife, eLife Sciences Publication, 2019, 8, ⟨10.7554/eLife.49485⟩
eLife, Vol 8 (2019)
International audience; Here we show that a major muscle specific isoform of the murine LINC complex protein SUN1 is required for efficient muscle regeneration. The nucleoplasmic domain of the isoform specifically binds to and inhibits Drosha, a key
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::902276e7b4d5cd66b456bd39c019a083
https://hal.sorbonne-universite.fr/hal-02573415/document
https://hal.sorbonne-universite.fr/hal-02573415/document
Autor:
Tsui Han Loo, Esther Sook Miin Wong, Brian Burke, Graham D. Wright, Arnette Shi Wei Wong, Alessandra Calvi, Colin L. Stewart
Publikováno v:
Developmental Biology. 407(2):321-330
One of the more dramatic examples of cellular reorganization occurs during spermiogenesis in which a roughly spherical spermatid is transformed into a mature sperm cell. A highlight of this process involves nuclear remodeling whereby the round sperma
Autor:
Tsui-Han Loo, Mohan K. Balasubramanian
Publikováno v:
The Journal of Cell Biology
p21-activated kinases (Paks) have been identified in a variety of eukaryotic cells as key effectors of the Cdc42 family of guanosine triphosphatases. Pak kinases play important roles in regulating the filamentous actin cytoskeleton. In this study, we
Autor:
Mitsuteru Ito, Carol A. Edwards, Tsui-Han Loo, Sarah E. Allen, Amanda N. Sferruzzi-Perri, Tomoko Kaneko-Ishino, Anne C. Ferguson-Smith, Fumitoshi Ishino, Moe Kitazawa, Colin L. Stewart, Bjorn T. Adalsteinsson
Publikováno v:
Development (Cambridge, England). 142(14)
The paternally expressed imprinted Retrotransposon-like 1 (Rtl1/Peg11) is a retrotransposon-derived gene that has evolved a function in eutherian placentation. Seven miRNAs, including miR-127, are processed from a maternally expressed antisense Rtl1
Publikováno v:
Molecular and Cellular Biology. 24:3849-3859
p21-activated kinases (PAKs) associate with a guanine nucleotide exchange factor, Pak-interacting exchange factor (PIX), which in turn binds the paxillin-associated adaptor GIT1 that targets the complex to focal adhesions. Here, a detailed structure-
Publikováno v:
Molecular and Cellular Biology. 20:6354-6363
The p21-activated kinase PAK is targeted to focal complexes (FCs) through interactions with the SH3 domains of the PAK-interacting exchange factor PIX and Nck. PIX is a Rac GTP exchange factor that also binds the G-protein-coupled receptor kinase-int