Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Tsuguri Toyomoto"'
Autor:
Tsuguri Toyomoto, Asami Sato, Maki Sugai, Takashi Kubota, Takahide Hayano, Seiichiro Fujisaki, Osamu Koiwai
Publikováno v:
Genes to Cells. 11:47-57
N regions at the junction of V, D and J DNA segments are synthesized with large protein complexes including terminal deoxynucleotidyltransferase (TdT) during V(D)J recombination in B- or T-cells. TdT directly binds to TdIF1, TdIF2, PCNA and the Ku70/
Autor:
Hiroko Yamamoto, Noriko Shimazaki, Shingo Toji, Sachiko Kuroda, Shirou Ibe, Reo Kaneko, Katsuyuki Tamai, Izumi Takebe, Kiyoko Fujita, Akiko Tanabe, Tsuguri Toyomoto, Tamami Kobayashi, Osamu Koiwai
Publikováno v:
Genes to Cells. 6:815-824
Background The repertoires of Ig and TcR are generated by a combinatorial rearrangement of variable (V), diversity (D), and joining (J) segments (V(D)J recombination) in B- and T-cells. Terminal deoxynucleotidyltransferase (TdT) adds extra nucleotide
Autor:
Noriko Shimazaki, Osamu Koiwai, Shingo Toji, Tomohiko Hasegawa, Kiyoko Fujita, Reo Kaneko, Katsuyuki Tamai, Hiroko Yamamoto, Shiro Ibe, Nobuyuki Yamashita, Akiko Tanabe, Tsuguri Toyomoto
Publikováno v:
Genes to Cells. 6:641-652
Background Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase that enhances Ig and TcR gene diversity in the N region in B- and T-cells. TdT is found as a member of a large protein complex in the lysate of the thymocytes. To elucidate the
Autor:
Seiichiro, Fujisaki, Asami, Sato, Tsuguri, Toyomoto, Takahide, Hayano, Maki, Sugai, Takashi, Kubota, Osamu, Koiwai
Publikováno v:
Genes to cells : devoted to molecularcellular mechanisms. 11(1)
N regions at the junction of V, D and J DNA segments are synthesized with large protein complexes including terminal deoxynucleotidyltransferase (TdT) during V(D)J recombination in B- or T-cells. TdT directly binds to TdIF1, TdIF2, PCNA and the Ku70/