Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Tsuguhiro Kaneda"'
Autor:
Naohiro Seo, Junko Nakamura, Tsuguhiro Kaneda, Hiroaki Tateno, Asako Shimoda, Takanori Ichiki, Koichi Furukawa, Jun Hirabayashi, Kazunari Akiyoshi, Hiroshi Shiku
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 3, Pp n/a-n/a (2022)
Abstract The development of a new large‐scale purification protocol is required for research on the reliable bioactivity and drug discovery of extracellular vesicles (EVs). To address this issue, herein, we propose an effective method for preparing
Externí odkaz:
https://doaj.org/article/ec048ebd4cd04199bbc9a4fcae2aff61
Autor:
Naoto Mamiya, Junko Hattori, Motohiro Hamaguchi, Urara Shigemi, Kazuyo Nakamura, Kayoko Shimizu, Saeko Fujisaki, Seiichiro Fujisaki, Shiro Ibe, Yoshiyuki Yokomaku, Tsuguhiro Kaneda, Makoto Utsumi
Publikováno v:
AIDS Research and Human Retroviruses. 25:15-21
To monitor active HIV-1 transmission in Nagoya, Japan, we have been determining the subtypes of HIV-1 infecting therapy-naive individuals who have newly visited the Nagoya Medical Center since 1997. The subtypes were determined by phylogenetic analys
Autor:
Naoto Mamiya, Seiichiro Fujisaki, Shiro Ibe, Junko Hattori, Kaori Sawaki, Motohiro Hamaguchi, Urara Shigemi, Tsuguhiro Kaneda, Yoshiyuki Yokomaku
Publikováno v:
AIDS Research and Human Retroviruses. 24:1121-1125
We analyzed a total of 12 near full-length genomes of drug-resistant HIV-1 spreading among therapy-naive individuals in Nagoya, Japan. Genomes comprised seven protease inhibitor (PI)-resistant viruses possessing an M46I (n = 6) or L90M mutation (n =
Autor:
Naoto Mamiya, Saeko Fujisaki, Yoshiyuki Yokomaku, Kazuyo Nakamura, Junko Hattori, Shiro Ibe, Motohiro Hamaguchi, Urara Shigemi, Tsuguhiro Kaneda, Takejiro Kazumi, Kayoko Shimizu, Seiichiro Fujisaki
Publikováno v:
AIDS Research and Human Retroviruses. 24:7-14
We studied the emergence of drug-resistant human immunodeficiency virus type 1 (HIV-1) with major amino acid mutations in 402 therapy-naive patients at Nagoya Medical Center, Japan, between 1999 and 2006. The mean prevalence of drug-resistant HIV-1 w
Autor:
Masaaki Takahashi, Naoto Mamiya, Shiro Ibe, Naoya Okumura, Tsuguhiro Kaneda, Motohiro Hamaguchi, Tatsuo Suzuki, Yuichi Kudaka, Atsushi Hirano
Publikováno v:
AIDS Research and Human Retroviruses. 23:983-987
The present study assessed the relationship between central nervous system (CNS) side effects and plasma concentrations of efavirenz (EFV) in Japanese HIV-1-infected patients. Subjects consisted of 69 HIV-1-infected patients (57 therapy-naive and 12
Autor:
Junko Hattori, Motohiro Hamaguchi, Naoya Okumura, Yumiko Yamazaki, Tsuguhiro Kaneda, Yukihiro Nishiyama, Masataka Uchiyama
Publikováno v:
Microbiology and Immunology. 51:193-200
Several reports have documented a better prognosis for HIV-1-infected patients co-infected with GBV-C, while other reports have contradicted such findings with the result that this issue remains controversial. We attempted to clarify the complicated
Autor:
Tsuguhiro Kaneda, Takayuki Morishita, Kaoru Wada, Hiromi Nagai, Makoto Utsumi, Yukihiro Nishiyama
Publikováno v:
Journal of Virological Methods. 124:157-165
A new estimation method for quantitation of HIV-1 DNA was established by introducing a pre-quantitation polymerase chain reaction (PCR) before conventional real-time PCR. Two alternative methods for estimating the copy number can be used: the first m
Autor:
Masao Yoshida, Tsuyoshi Oki, Tatsuo Suzuki, Masaaki Takahashi, Naoya Okumura, Tsuguhiro Kaneda
Publikováno v:
Biological and Pharmaceutical Bulletin. 28:1286-1290
We developed a simple HPLC method for the simultaneous quantitative determination of seven HIV protease inhibitors: amprenavir (APV), atazanavir (ATV), indinavir (IDV), lopinavir (LPV), nelfinavir (NFV), ritonavir (RTV), saquinavir (SQV), and a nonnu
Autor:
Naoto Mamiya, Masahiko Nakai, Katsuo Yamanaka, Koichi Nagaoka, Hirotaka Ito, Makoto Utsumi, Tsuyoshi Oki, Yoshiko Usami, Tsuguhiro Kaneda, Masafumi Sagisaka
Publikováno v:
Biological & Pharmaceutical Bulletin. 27:261-265
The pharmacokinetic parameters of lopinavir (LPV) were examined by administering Kaletra (LPV+ritonavir) to 8 healthy Japanese volunteers both in the fasting and postprandial conditions. LPV showed a biphasic decline, which was slower in the initial
Autor:
Katsuhiko Sato, Kaoru Wada, Shiro Ibe, Takayuki Morishita, Junko Hattori, Tsuguhiro Kaneda, Makoto Utsumi, Hiromi Nagai
Publikováno v:
Microbiology and Immunology. 47:759-763
Since the discovery of GB virus-C (GBV-C) and hepatitis G virus (HGV), many studies have been performed. These viruses are now known to be parenterally, as well as sexually transmitted. A phylogenetic analysis also revealed that GBV-C has five major