MS-DIAL 5 multimodal mass spectrometry data mining unveils lipidome complexities.

Autor: Takeda H; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan.; RIKEN Center for Brain Science, 2-1 Hirosawa, Wako, Saitama, 351-0106, Japan., Matsuzawa Y; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Takeuchi M; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Takahashi M; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan., Nishida K; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Harayama T; Institut de Pharmacologie Moléculaire et Cellulaire, Université Côte d'Azur - CNRS UMR7275 - Inserm U1323, 660 Route des Lucioles, 06560, Valbonne, France. harayama@ipmc.cnrs.fr.; Institute of Global Innovation Research, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan. harayama@ipmc.cnrs.fr., Todoroki Y; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Shimizu K; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Sakamoto N; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Oka T; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Maekawa M; Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo, 105-8512, Japan., Chung MH; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Kurizaki Y; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Kiuchi S; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Tokiyoshi K; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Buyantogtokh B; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Kurata M; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Kvasnička A; Faculty of Medicine and Dentistry, Palacký University Olomouc, Hněvotínská 3, 779 00, Olomouc, Czech Republic.; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc, Zdravotníků 248/7, 779 00, Olomouc, Czech Republic.; Department of Medical Biochemistry, Oslo University Hospital, Sognsvannsveien 20, 0372, Oslo, Norway., Takeda U; K.K. ABSciex Japan, Shinagawa, Tokyo, 140-0001, Japan., Uchino H; Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo, 105-8512, Japan.; RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan., Hasegawa M; Department of Applied Biological Science, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo, 183-8509, Japan., Miyamoto J; Department of Applied Biological Science, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo, 183-8509, Japan., Tanabe K; Innovative Technology Laboratories, AGC Inc., 1-1 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045, Japan., Takeda S; Innovative Technology Laboratories, AGC Inc., 1-1 Suehiro-cho, Tsurumi-ku, Yokohama, 230-0045, Japan., Mori T; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan., Kumakubo R; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Tanaka T; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Yoshino T; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan., Okamoto M; Shimadzu Corporation, 1 Nishinokyo Kuwabara-cho, Nakagyo-ku, Kyoto, 604-8511, Japan., Takahashi H; Shimadzu Corporation, 1 Nishinokyo Kuwabara-cho, Nakagyo-ku, Kyoto, 604-8511, Japan., Arita M; Graduate School of Pharmaceutical Sciences, Keio University, Minato-ku, Tokyo, 105-8512, Japan. marita@keio.jp.; RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan. marita@keio.jp.; Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan. marita@keio.jp., Tsugawa H; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan. htsugawa@go.tuat.ac.jp.; RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan. htsugawa@go.tuat.ac.jp.; Institute of Global Innovation Research, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo, 184-8588, Japan. htsugawa@go.tuat.ac.jp.; RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa, 230-0045, Japan. htsugawa@go.tuat.ac.jp.; Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan. htsugawa@go.tuat.ac.jp.

Publikováno v: Nature communications [Nat Commun] 2024 Nov 28; Vol. 15 (1), pp. 9903. Date of Electronic Publication: 2024 Nov 28.

Macrophage-depleted young mice are beneficial in vivo models to assess the translocation of Klebsiella pneumonia from the gastrointestinal tract to the liver in the elderly.

Autor: Tsugawa H; Transkingdom Signaling Research Unit, Division of Host Defense Mechanism, Tokai University School of Medicine, Isehara, 259-1193, Japan. Electronic address: tsugawa.hitoshi.r@tokai.ac.jp., Tsubaki S; Transkingdom Signaling Research Unit, Division of Host Defense Mechanism, Tokai University School of Medicine, Isehara, 259-1193, Japan., Tanaka R; Department of Immunology, Division of Host Defense Mechanism, Tokai University School of Medicine, Isehara, 259-1193, Japan., Nashimoto S; Transkingdom Signaling Research Unit, Division of Host Defense Mechanism, Tokai University School of Medicine, Isehara, 259-1193, Japan., Imai J; Department of Clinical Health Science, Tokai University School of Medicine, Isehara, 259-1193, Japan., Matsuzaki J; Division of Pharmacotherapeutics, Keio University Faculty of Pharmacy, Tokyo, 105-8512, Japan., Hozumi K; Department of Immunology, Division of Host Defense Mechanism, Tokai University School of Medicine, Isehara, 259-1193, Japan.

Publikováno v: Microbes and infection [Microbes Infect] 2024 Nov-Dec; Vol. 26 (8), pp. 105371. Date of Electronic Publication: 2024 Jun 05.

Concordant inter-laboratory derived concentrations of ceramides in human plasma reference materials via authentic standards.

Autor: Torta F; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore.; Precision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119077, Singapore.; Signature Research Program in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore (NUS) Medical School, Singapore, 169857, Singapore., Hoffmann N; Institute for Bio- and Geosciences (IBG-5), Forschungszentrum Jülich GmbH, 52428, Jülich, Germany.; Department of Analytical Chemistry, University of Vienna, Vienna, Austria., Burla B; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore., Alecu I; Neural Regeneration Laboratory, Ottawa Institute of Systems Biology, Ottawa Brain and Mind Research Institute, Department of Biochemistry, Microbiology, and Immunology, and Department of Chemistry, Centre for Catalysis Research and Innovation, University of Ottawa, Ottawa, K1H 8M5, Canada., Arita M; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan., Bamba T; Division of Metabolomics Center, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, 3‑1‑1, Maidashi, Higashi‑ku, Fukuoka, 812‑8582, Japan., Bennett SAL; Neural Regeneration Laboratory, Ottawa Institute of Systems Biology, Ottawa Brain and Mind Research Institute, Department of Biochemistry, Microbiology, and Immunology, and Department of Chemistry, Centre for Catalysis Research and Innovation, University of Ottawa, Ottawa, K1H 8M5, Canada., Bertrand-Michel J; MetaboHUBMetaToul Facility, I2MC U1297 Inserm, Toulouse, France., Brügger B; Heidelberg University Biochemistry Center (BZH), Im Neuenheimer Feld 328, 69120, Heidelberg, Germany., Cala MP; Metabolomics Core Facility-MetCore, Universidad de los Andes, Bogotá, 111711, Colombia., Camacho-Muñoz D; Laboratory for Lipidomics and Lipid Biology, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9NT, United Kingdom., Checa A; Unit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Chen M; Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada., Chocholoušková M; Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10, Pardubice, Czech Republic., Cinel M; Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; Baker Department of Cardiovascular Research, Translation and Implementation, La Trobe University, Bundoora, VIC, 3086, Australia., Chu-Van E; Université Paris-Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), MetaboHUB, F-91191, Gif sur Yvette, France., Colsch B; Université Paris-Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), MetaboHUB, F-91191, Gif sur Yvette, France., Coman C; Department of Analytical Chemistry, University of Vienna, Vienna, Austria., Connell L; Avanti Polar Lipids, Alabaster, AL, USA., Sousa BC; Babraham Institute, Babraham Research Campus, Cambridge, MA, CB22 3AT, USA., Dickens AM; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520, Turku, Finland.; Department of Chemistry, University of Turku, Turku, Finland., Fedorova M; Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, University of Leipzig, 04013, Leipzig, Germany.; Center for Biotechnology and Biomedicine, University of Leipzig, 04013, Leipzig, Germany.; Center of Membrane Biochemistry and Lipid Research, Faculty of Medicine Carl Gustav Carus of TU Dresden, 01307, Dresden, Germany., Eiríksson FF; Faculty of Pharmaceutical Sciences, University of Iceland, Reykjavik, Iceland.; ArcticMass, Reykjavik, Iceland., Gallart-Ayala H; Metabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Ghorasaini M; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333ZA, Leiden, The Netherlands., Giera M; Center for Proteomics and Metabolomics, Leiden University Medical Center, 2333ZA, Leiden, The Netherlands., Guan XL; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, 636921, Singapore., Haid M; Metabolomics and Proteomics Core, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany., Hankemeier T; Metabolomics and Analytics Centre, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Harms A; Metabolomics and Analytics Centre, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Höring M; University Hospital of Regensburg, Institute of Clinical Chemistry and Laboratory Medicine, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany., Holčapek M; Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10, Pardubice, Czech Republic., Hornemann T; Institute of Clinical Chemistry, University Zurich, 8952, Schlieren, Switzerland., Hu C; State Key Laboratory of Medical Proteomics, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China., Hülsmeier AJ; Institute of Clinical Chemistry, University Zurich, 8952, Schlieren, Switzerland., Huynh K; Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; Baker Department of Cardiovascular Research, Translation and Implementation, La Trobe University, Bundoora, VIC, 3086, Australia., Jones CM; Chemical Science Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA., Ivanisevic J; Metabolomics Platform, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland., Izumi Y; Division of Metabolomics Center, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, 3‑1‑1, Maidashi, Higashi‑ku, Fukuoka, 812‑8582, Japan., Köfeler HC; Core Facility Mass Spectrometry, Medical University of Graz, 8010, Graz, Austria., Lam SM; LipidALL Technologies, Changzhou, 213000, Jiangshu, China.; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China., Lange M; Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, University of Leipzig, 04013, Leipzig, Germany.; Center for Biotechnology and Biomedicine, University of Leipzig, 04013, Leipzig, Germany., Lee JC; Department of Chemistry, Yonsei University, Seoul, 03722, South Korea., Liebisch G; University Hospital of Regensburg, Institute of Clinical Chemistry and Laboratory Medicine, Franz-Josef-Strauß-Allee 11, 93053, Regensburg, Germany., Lippa K; Chemical Science Division, National Institute of Standards and Technology, Gaithersburg, MD, 20899, USA., Lopez-Clavijo AF; Babraham Institute, Babraham Research Campus, Cambridge, MA, CB22 3AT, USA., Manzi M; Centro de Investigaciones en Bionanociencias (CIBION), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Godoy Cruz 2390, C1425FQD, Ciudad de Buenos Aires, Argentina.; Departamento de Fisiología, Biología Molecular y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Intendente Güiraldes, 2160 C1428EGA, Buenos Aires, Argentina.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Departamento de Desarrollo Analítico y Control de Procesos, Instituto Nacional de Tecnología Industrial, Av. General Paz 5445, B1650WAB, Buenos Aires, Argentina., Martinefski MR; Centro de Investigaciones en Bionanociencias (CIBION), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Godoy Cruz 2390, C1425FQD, Ciudad de Buenos Aires, Argentina.; Universidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Departamento de Ciencias Químicas, Buenos Aires, Junin 954, Junin, C1113AAD, CABA, Argentina., Math RGH; National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India., Mayor S; National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India., Meikle PJ; Baker Heart and Diabetes Institute, Melbourne, VIC, 3004, Australia.; Baker Department of Cardiovascular Research, Translation and Implementation, La Trobe University, Bundoora, VIC, 3086, Australia., Monge ME; Centro de Investigaciones en Bionanociencias (CIBION), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Godoy Cruz 2390, C1425FQD, Ciudad de Buenos Aires, Argentina., Moon MH; Department of Chemistry, Yonsei University, Seoul, 03722, South Korea., Muralidharan S; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore.; National Centre for Biological Sciences, Tata Institute of Fundamental Research, Bangalore, Karnataka, 560065, India., Nicolaou A; Laboratory for Lipidomics and Lipid Biology, Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9NT, United Kingdom.; Lydia Becker Institute of Immunology and Inflammation; Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Manchester, M13 9NT, United Kingdom., Nguyen-Tran T; Neural Regeneration Laboratory, Ottawa Institute of Systems Biology, Ottawa Brain and Mind Research Institute, Department of Biochemistry, Microbiology, and Immunology, and Department of Chemistry, Centre for Catalysis Research and Innovation, University of Ottawa, Ottawa, K1H 8M5, Canada., O'Donnell VB; Systems Immunity Research Institute, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK., Orešič M; Turku Bioscience Centre, University of Turku and Åbo Akademi University, 20520, Turku, Finland.; School of Medical Sciences, Faculty of Medicine and Health, Örebro University, 702 81, Örebro, Sweden., Ramanathan A; Institute for Stem Cell Science and Regenerative Medicine, 560065, Bangalore, India., Riols F; Metabolomics and Proteomics Core, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany., Saigusa D; Laboratory of Biomedical and Analytical Sciences, Faculty of Pharma-Science, Teikyo University, 2-11-1 Kaga, Itabashi-ku, Tokyo, 173-8605, Japan.; Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8573, Japan., Schock TB; Chemical Science Division, National Institute of Standards and Technology, Charleston, SC, 29412, USA., Schwartz-Zimmermann H; Christian Doppler Laboratory for Innovative Gut Health Concepts of Livestock, Institute of Bioanalytics and Agro-Metabolomics, Department of Agrobiotechnology (IFATulln), University of Natural Resources and Life Sciences, Vienna (BOKU), Konrad-Lorenz-Str. 20, 3430, Tulln, Austria., Shui G; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, 100101, China., Singh M; Metabolomics and Analytics Centre, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Takahashi M; Division of Metabolomics Center, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, 3‑1‑1, Maidashi, Higashi‑ku, Fukuoka, 812‑8582, Japan., Thorsteinsdóttir M; Faculty of Pharmaceutical Sciences, University of Iceland, Reykjavik, Iceland.; ArcticMass, Reykjavik, Iceland., Tomiyasu N; Division of Metabolomics Center, Medical Research Center for High Depth Omics, Medical Institute of Bioregulation, Kyushu University, 3‑1‑1, Maidashi, Higashi‑ku, Fukuoka, 812‑8582, Japan., Tournadre A; MetaboHUBMetaToul Facility, I2MC U1297 Inserm, Toulouse, France., Tsugawa H; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan.; RIKEN Center for Sustainable Resource Science, Yokohama, Japan.; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan., Tyrrell VJ; Systems Immunity Research Institute, School of Medicine, Cardiff University, Heath Park, Cardiff, CF14 4XN, UK., van der Gugten G; St. Paul's Hospital, Department of Pathology and Laboratory Medicine, Vancouver, BC, Canada., Wakelam MO; Babraham Institute, Babraham Research Campus, Cambridge, MA, CB22 3AT, USA., Wheelock CE; Unit of Integrative Metabolomics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.; Department of Respiratory Medicine and Allergy, Karolinska University Hospital, Stockholm, Sweden., Wolrab D; Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Studentská 573, 532 10, Pardubice, Czech Republic., Xu G; State Key Laboratory of Medical Proteomics, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China., Xu T; State Key Laboratory of Medical Proteomics, CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China., Bowden JA; Department of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32610, USA., Ekroos K; Lipidomics Consulting Ltd., Espoo, Finland. kim@lipidomicsconsulting.com., Ahrends R; Department of Analytical Chemistry, University of Vienna, Vienna, Austria. robert.ahrends@univie.ac.at., Wenk MR; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore, 117456, Singapore. mwenk@hbku.edu.qa.; Precision Medicine Translational Research Programme and Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119077, Singapore. mwenk@hbku.edu.qa.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar. mwenk@hbku.edu.qa.

Publikováno v: Nature communications [Nat Commun] 2024 Oct 03; Vol. 15 (1), pp. 8562. Date of Electronic Publication: 2024 Oct 03.

Characterization of Entamoeba fatty acid elongases; validation as targets and provision of promising leads for new drugs against amebiasis.

Autor: Mi-Ichi F; Central Laboratory, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan.; Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, Japan., Tsugawa H; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan.; Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan., Vo TK; Central Laboratory, Institute of Tropical Medicine (NEKKEN), Nagasaki University, Nagasaki, Japan.; Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, Japan., Kurizaki Y; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan., Yoshida H; Division of Molecular and Cellular Immunoscience, Department of Biomolecular Sciences, Faculty of Medicine, Saga University, Saga, Japan., Arita M; Laboratory for Metabolomics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan.; Division of Physiological Chemistry and Metabolism, Graduate School of Pharmaceutical Sciences, Keio University, Tokyo, Japan.; Human Biology-Microbiome-Quantum Research Center (WPI-Bio2Q), Keio University, Tokyo, Japan.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Aug 22; Vol. 20 (8), pp. e1012435. Date of Electronic Publication: 2024 Aug 22 (Print Publication: 2024).

Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer's Disease Neuroimaging Initiative cohort.

Autor: Oka T; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan., Matsuzawa Y; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan., Tsuneyoshi M; Human Biology Integration Foundation, Eisai Co., Ltd., Ibaraki, Japan., Nakamura Y; Human Biology Integration Foundation, Eisai Co., Ltd., Ibaraki, Japan., Aoshima K; Microbes & Host Defense Domain, Eisai Co., Ltd., Ibaraki, Japan.; School of Integrative and Global Majors, University of Tsukuba, Ibaraki, Japan., Tsugawa H; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan. htsugawa@go.tuat.ac.jp.; RIKEN Center for Sustainable Resource Science, Yokohama, Japan. htsugawa@go.tuat.ac.jp.; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. htsugawa@go.tuat.ac.jp.; Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan. htsugawa@go.tuat.ac.jp.

Publikováno v: Scientific reports [Sci Rep] 2024 Apr 02; Vol. 14 (1), pp. 6797. Date of Electronic Publication: 2024 Apr 02.