Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Tsubasa Chikada"'
Autor:
Takehiro Fukami, Yui Mazaki, Kenichi Washizuka, Hideaki Niwa, Takeshi Tsumura, Hiroo Koyama, Yuko Kano, Yasuko Koda, Fumiyuki Shirai, Kouichi Kitamura, Yoko Yashiroda, Anna Mizutani, Hitomi Yuki, Eiki Shitara, Hiroyuki Seimiya, Teruki Honma, Shin Sato, Tsubasa Chikada, Minoru Yoshida, Masayuki Okue, Takashi Watanabe, Takashi Umehara, Yukiko Muramatsu, Akiko Nagamori, Myung-Kyu Jang, Haruka Yoshida, Mikako Shirouzu
Publikováno v:
Journal of medicinal chemistry. 63(8)
Tankyrases (TNKS/TNKS2) belong to the poly(ADP-ribose) polymerase family. Inhibition of their enzymatic activities attenuates the Wnt/β-catenin signaling, which plays an important role in cancer pathogenesis. We previously reported the discovery of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30c01958ef416b8aff1cab18d74f999
https://pubmed.ncbi.nlm.nih.gov/32202790
https://pubmed.ncbi.nlm.nih.gov/32202790
Autor:
Tsubasa Chikada, Minoru Yoshida, Yukiko Muramatsu, Yoko Yashiroda, Takehiro Fukami, Fumiyuki Shirai, Masayuki Okue, Anna Mizutani, Haruka Yoshida, Hiroyuki Seimiya, Takeshi Tsumura
Publikováno v:
Cancer Science
Aberrant activation of Wnt/β-catenin signaling causes tumorigenesis and promotes the proliferation of colorectal cancer cells. Porcupine inhibitors, which block secretion of Wnt ligands, may have only limited clinical impact for the treatment of col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108b4f5f96dc0c462e0db92f54d35b64
http://europepmc.org/articles/PMC6272098
http://europepmc.org/articles/PMC6272098
Autor:
Kaori Kaneda, Yuji Tabata, Naomi Takei-Masuda, Sho Takahata, Yu Nagira, Xiaoying Hui, Masahiro Nomoto, Natsuki Kubota-Ishida, Howard I. Maibach, Tsubasa Chikada, Kazunori Maebashi
Publikováno v:
Antimicrobial agents and chemotherapy, vol 62, iss 1
ME1111 is a novel antifungal agent currently under clinical development as a topical onychomycosis treatment. A major challenge in the application of topical onychomycotics is penetration and dissemination of antifungal agent into the infected nail p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9606d621f3ccbe3379f8bba134472b2
https://europepmc.org/articles/PMC5740379/
https://europepmc.org/articles/PMC5740379/
Publikováno v:
Archives of Biochemistry and Biophysics. 517:123-130
A previous report demonstrated that treatment of human hepatocytes with phenobarbital, an activator of nuclear receptor constitutive androstane receptor (CAR), increases mRNA levels of an efflux transporter ABCG2, which is involved in the excretion o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c6056cae88b2f4c20b63a14dc5960e5
https://doi.org/10.1016/j.abb.2011.10.014
https://doi.org/10.1016/j.abb.2011.10.014
Autor:
Yasushi Yamazoe, Kiyoshi Nagata, Kouichi Yoshinari, Shuko Tachibana, Takayoshi Toriyabe, Tsubasa Chikada
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 37(8)
ABCB1 (P-glycoprotein) is an efflux transporter that limits the cellular uptake levels of various drugs in intestine, brain, and other tissues. The expression of human ABCB1 has recently been reported to be under the control of nuclear receptor NR1I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017fa7ffe403997851e18d79abd02787
https://pubmed.ncbi.nlm.nih.gov/19460946
https://pubmed.ncbi.nlm.nih.gov/19460946