Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Tsu Yi Su"'
Autor:
Tsu-Yi Su, Julia Hauenstein, Ece Somuncular, Özge Dumral, Elory Leonard, Charlotte Gustafsson, Efthymios Tzortzis, Aurora Forlani, Anne-Sofie Johansson, Hong Qian, Robert Månsson, Sidinh Luc
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Age is a risk factor for hematologic malignancies. Attributes of the aging hematopoietic system include increased myelopoiesis, impaired adaptive immunity, and a functional decline of the hematopoietic stem cells (HSCs) that maintain hematop
Externí odkaz:
https://doaj.org/article/ce8fe9bb60494b84ad3652fa933d6098
Autor:
Kun-Yang Lin, Wen-Der Wang, Chi-Hung Lin, Elham Rastegari, Yu-Han Su, Yu-Tzu Chang, Yung-Feng Liao, Yi-Chieh Chang, Haiwei Pi, Bo-Yi Yu, Shu-Hwa Chen, Chung-Yen Lin, Mei-Yeh Lu, Tsu-Yi Su, Fei-Yang Tzou, Chih-Chiang Chan, Hwei-Jan Hsu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Retrotransposons are known to be involved in aging. Here the authors show that the retrotransposon silencer Piwi contributes to germline stem cell loss during aging in Drosophila.
Externí odkaz:
https://doaj.org/article/f818031002264c058f9fd632e6d09a5a
Autor:
Fei-Yang Tzou, Tsu-Yi Su, Wan-Syuan Lin, Han-Chun Kuo, Yu-Lian Yu, Yu-Han Yeh, Chung-Chih Liu, Ching-Hua Kuo, Shu-Yi Huang, Chih-Chiang Chan
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108972- (2021)
Summary: Disruption of sphingolipid homeostasis is known to cause neurological disorders, but the mechanisms by which specific sphingolipid species modulate pathogenesis remain unclear. The last step of de novo sphingolipid synthesis is the conversio
Externí odkaz:
https://doaj.org/article/d549c70fb1f546f3ba3ccb7c7a1fdb6b
Hematopoiesis is maintained by hematopoietic stem cells (HSCs) that replenish the blood lineages throughout life. It is well-established that the HSC pool is functionally heterogeneous consisting of cells differing in longevity, self-renewal ability,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ce11a104ac3a7aad64595b38af1c1a4
https://doi.org/10.1101/2023.03.20.533430
https://doi.org/10.1101/2023.03.20.533430
Publikováno v:
Stem Cells Translational Medicine; Nov2023, Vol. 12 Issue 11, p720-726, 7p
Autor:
Wen-Der Wang, Yu Tzu Chang, Chung Yen Lin, Yu Han Su, Fei Yang Tzou, Haiwei Pi, Kun-Yang Lin, Hwei-Jan Hsu, Chi Hung Lin, Elham Rastegari, Bo Yi Yu, Mei Yeh Lu, Tsu Yi Su, Yung-Feng Liao, Yi Chieh Chang, Shu Hwa Chen, Chih-Chiang Chan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Transposons are known to participate in tissue aging, but their effects on aged stem cells remain unclear. Here, we report that in the Drosophila ovarian germline stem cell (GSC) niche, aging-related reductions in expression of Piwi (a transposon sil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26e4eb16133b173bdc3cfc5b5777c0bc
https://doaj.org/article/f818031002264c058f9fd632e6d09a5a
https://doaj.org/article/f818031002264c058f9fd632e6d09a5a
Autor:
Göran Larson, Jonas Nilsson, Hiroshi Nakato, Fredrik Noborn, Masahiko Takemura, Nanako Bowden, Tsu Yi Su, Eriko Nakato, Sarah E. Baker
Publikováno v:
Molecular Biology of the Cell
Proteoglycans, a class of carbohydrate-modified proteins, often modulate growth factor signaling on the cell surface. However, the molecular mechanism by which proteoglycans regulate signal transduction is largely unknown. In this study, using a rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ed50be7063cce4f9b70d1f8d735296
https://doi.org/10.1091/mbc.e19-06-0327
https://doi.org/10.1091/mbc.e19-06-0327
Autor:
Ece Somuncular, Julia Hauenstein, Prajakta Khalkar, Anne-Sofie Johansson, Özge Dumral, Nicolai S. Frengen, Charlotte Gustafsson, Giuseppe Mocci, Tsu-Yi Su, Hugo Brouwer, Christine L. Trautmann, Michael Vanlandewijck, Stuart H. Orkin, Robert Månsson, Sidinh Luc
Publikováno v:
Stem cell reports. 17(7)
Hematopoiesis is maintained by functionally diverse lineage-biased hematopoietic stem cells (HSCs). The functional significance of HSC heterogeneity and the regulatory mechanisms underlying lineage bias are not well understood. However, absolute puri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc910d1a5dca0a11b52eb767117edc34
https://pubmed.ncbi.nlm.nih.gov/35714596
https://pubmed.ncbi.nlm.nih.gov/35714596
Autor:
Fei-Yang Tzou, Tsu-Yi Su, Chih-Chiang Chan, Yu-Han Yeh, Chung-Chih Liu, Wan-Syuan Lin, Ching-Hua Kuo, Han-Chun Kuo, Shu-Yi Huang, Yu-Lian Yu
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108972-(2021)
Summary: Disruption of sphingolipid homeostasis is known to cause neurological disorders, but the mechanisms by which specific sphingolipid species modulate pathogenesis remain unclear. The last step of de novo sphingolipid synthesis is the conversio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aac1c592c33c960cd0001c40a572f0d
https://pubmed.ncbi.nlm.nih.gov/33852856
https://pubmed.ncbi.nlm.nih.gov/33852856
Autor:
Yu-Lian Yu, Chung-Chih Liu, Chih-Chiang Chan, Yu-Han Yeh, Tsu-Yi Su, Shu-Yi Huang, Fei-Yang Tzou
SummaryDisruption of sphingolipid homeostasis has been shown to cause neurological disorders. How specific sphingolipid species modulate the pathogenesis remains unknown. The last step of sphingolipid de novo synthesis is the conversion of dihydrocer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b6b8fd736fdd66a0330a1051e38001
https://doi.org/10.1101/2020.06.01.128579
https://doi.org/10.1101/2020.06.01.128579