Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Tsu T. Chuang"'
Autor:
Lauren R. Sheckler, Irving L. Weissman, Stephen A. Stimpson, Massimiliano Cerletti, Joshua J. Schroeder, Amy J. Wagers, John T. Moore, Matthew A. Inlay, Tata Nageswara Rao, Dave J. Becherer, Derrick J. Rossi, Tsu T. Chuang, Deepti A. Cole
Publikováno v:
SSRN Electronic Journal.
Skeletal muscle normally exhibits robust regenerative potential in youth; however, myogenic activity declines with age, resulting in defective muscle repair after injury. In this study, we identified signaling pathways in mouse muscle stem cells that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb09ee48d13552e4d63a0315a8951b12
https://doi.org/10.2139/ssrn.3244794
https://doi.org/10.2139/ssrn.3244794
Publikováno v:
British Journal of Pharmacology. 155:434-440
Background and purpose: The beneficial effect of 5-HT6 receptor antagonism in cognition remains controversial. This study has been undertaken to reassess the cognition enhancing properties of acute vs subchronic treatment with the selective 5-HT6 rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1b5b51c1ce9cedcdbe819bfa6a889dc
https://doi.org/10.1038/bjp.2008.281
https://doi.org/10.1038/bjp.2008.281
Autor:
Beatriz Marcos, S W Tsang, Mitchell K.P. Lai, Paul T. Francis, Monica Garcia-Alloza, Francisco J. Gil-Bea, Christopher Chen, María J. Ramírez, Tsu T. Chuang
Publikováno v:
Monica Garcia-Alloza
ResearcherID
ResearcherID
We studied the hypothesis that disturbances in 5-HT_{6} receptor function in the temporal cortex may contribute to clinical symptoms of Alzheimer's disease (AD). 5-HT_{6} density and 5-HT levels were significantly decreased in a cohort of AD patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa70037e3d4d24fbd7f2a5f1ca014a4
https://doi.org/10.3233/jad-2008-14104
https://doi.org/10.3233/jad-2008-14104
Autor:
Tania L. Mead, Peter Henry Milner, Leann P. Quinn, Nigel Deeks, Giancarlo Trani, Brenda K. Trail, Michael A. Briggs, Christopher N. Johnson, Andrew D. Medhurst, Alison M. Ray, Abir A. Khazragi, Tania O. Stean, David R. Witty, Stuart M. Baddeley, Geoffrey Stemp, Rivers Dean Andrew, Tsu T. Chuang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5698-5700
Starting from a benzazepine sulfonamide 5-HT(6) receptor antagonist lead with limited brain penetration, application of a strategy of conformational constraint and reduction of hydrogen bond donor count led to a novel series of tricyclic derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37fdec6da30eb144f3f300af260903a1
https://doi.org/10.1016/j.bmcl.2008.08.010
https://doi.org/10.1016/j.bmcl.2008.08.010
Publikováno v:
Synapse (New York, N.Y.). 63(9)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2a3a1eead58eceab9957451a1172870
https://pubmed.ncbi.nlm.nih.gov/19504619
https://pubmed.ncbi.nlm.nih.gov/19504619
Autor:
Christopher N. Johnson, Alison M. Ray, Brenda K. Trail, Andrew G. Foley, Leann P. Quinn, Mahmood Ahmed, Andrew D. Medhurst, Tania O. Stean, David R. Witty, Warren D. Hirst, Neil Upton, Tsu T. Chuang, David Sunter
Publikováno v:
Alzheimer's & Dementia. 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f376f1ee35e3c280298c098feaef2213
https://doi.org/10.1016/j.jalz.2008.05.2397
https://doi.org/10.1016/j.jalz.2008.05.2397