Zobrazeno 1 - 10
of 215
pro vyhledávání: '"Tsonwin, Hai"'
Autor:
Zhen Lu, Jinyun Chen, Pengfei Yu, Matthew J. Atherton, Jun Gui, Vivek S. Tomar, Justin D. Middleton, Neil T. Sullivan, Sunil Singhal, Subin S. George, Ashley G. Woolfork, Aalim M. Weljie, Tsonwin Hai, Evgeniy B. Eruslanov, Serge Y. Fuchs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Dendritic cells (DC) present tumour antigens to T cells but this process is defective in the tumour microenvironment. Here the authors find that downregulation of cholesterol 25-hydroxylase underlies defective cross presentation of tumour antigens.
Externí odkaz:
https://doaj.org/article/6f99c246674341cbadfcbbf971df3ad6
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 19, p 10280 (2021)
Previously, we showed that mice treated with cyclophosphamide (CTX) 4 days before intravenous injection of breast cancer cells had more cancer cells in the lung at 3 h after cancer injection than control counterparts without CTX. At 4 days after its
Externí odkaz:
https://doaj.org/article/6798df170420483cbe60d6ec714cf79c
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7356 (2021)
Previously, we showed that chemotherapy paradoxically exacerbated cancer cell colonization at the secondary site in a manner dependent on Atf3, a stress-inducible gene, in the non-cancer host cells. Here, we present evidence that this phenotype is es
Externí odkaz:
https://doaj.org/article/dce1f2bece1c4d9b988fcd5a6cc5b6a5
Autor:
Roy Kalfon, Tom Friedman, Shir Eliachar, Rona Shofti, Tali Haas, Lilach Koren, Jacob D Moskovitz, Tsonwin Hai, Ami Aronheim
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0213081 (2019)
c-Jun dimerization protein (JDP2) and Activating Transcription Factor 3 (ATF3) are closely related basic leucine zipper proteins. Transgenic mice with cardiac expression of either JDP2 or ATF3 showed maladaptive remodeling and cardiac dysfunction. Su
Externí odkaz:
https://doaj.org/article/b7e59c89d8b64732b6df441aee01e741
Autor:
Samson T. Jacob, Kalpana Ghoshal, Tsonwin Hai, Periannan Kuppusamy, Anna Bratasz, Wendy Frankel, Stefan Costinean, Bo Wang, Thomas Kaffenberger, Satavisha Roy, Sarmila Majumder
Supplementary Methods, Table 1, Figures 1-8 from Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6b30335e25564455cda8c4542693d5
https://doi.org/10.1158/0008-5472.22388933
https://doi.org/10.1158/0008-5472.22388933
Autor:
Saška Brajkovic, Mourad Ferdaoussi, Valérie Pawlowski, Hélène Ezanno, Valérie Plaisance, Erik Zmuda, Tsonwin Hai, Jean-Sébastien Annicotte, Gérard Waeber, Amar Abderrahmani
Publikováno v:
Journal of Diabetes Research, Vol 2016 (2016)
Chronic intake of saturated free fatty acids is associated with diabetes and may contribute to the impairment of functional beta cell mass. Mitogen activated protein kinase 8 interacting protein 1 also called islet brain 1 (IB1) is a candidate gene f
Externí odkaz:
https://doaj.org/article/d2d61d7052cd4e23b7a7b55d79d476fa
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3333 (2018)
An emerging picture in cancer biology is that, paradoxically, chemotherapy can actively induce changes that favor cancer progression. These pro-cancer changes can be either inside (intrinsic) or outside (extrinsic) the cancer cells. In this review, w
Externí odkaz:
https://doaj.org/article/5abbe877dc844e88973b5e473be035e8
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 12, Iss 7, Pp 527-538 (2010)
The mechanisms underlying the proapoptotic effect of the chemotherapeutic agent, cisplatin, are largely undefined. Understanding the mechanisms regulating cisplatin cytotoxicity may uncover strategies to enhance the efficacy of this important therape
Externí odkaz:
https://doaj.org/article/5184d24dd7e84617995769c2f5379406
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 7356, p 7356 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 14; Pages: 7356
International Journal of Molecular Sciences; Volume 22; Issue 14; Pages: 7356
Previously, we showed that chemotherapy paradoxically exacerbated cancer cell colonization at the secondary site in a manner dependent on Atf3, a stress-inducible gene, in the non-cancer host cells. Here, we present evidence that this phenotype is es
Autor:
Justin D, Middleton, Jared, Fehlman, Subhakeertana, Sivakumar, Daniel G, Stover, Tsonwin, Hai
Publikováno v:
International Journal of Molecular Sciences
Previously, we showed that chemotherapy paradoxically exacerbated cancer cell colonization at the secondary site in a manner dependent on Atf3, a stress-inducible gene, in the non-cancer host cells. Here, we present evidence that this phenotype is es