Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tsonko M, Tsonkov"'
Autor:
Christina Birkedahl, Falk-Petersen, Tsonko M, Tsonkov, Malene Sofie, Nielsen, Kasper, Harpsøe, Christoffer, Bundgaard, Bente, Frølund, Uffe, Kristiansen, David E, Gloriam, Petrine, Wellendorph
Publikováno v:
Scientific Reports
Brain GABAΑ receptors are ionotropic receptors belonging to the class of Cys-loop receptors and are important drug targets for the treatment of anxiety and sleep disorders. By screening a compound library (2,112 compounds) at recombinant human α4β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e0f78437ba78a2e82173300d259c6a6
https://pubmed.ncbi.nlm.nih.gov/32572053
https://pubmed.ncbi.nlm.nih.gov/32572053
Autor:
Kasper Harpsøe, Christina Birkedahl Falk-Petersen, Tsonko M. Tsonkov, Uffe Kristiansen, David E. Gloriam, Malene Sofie Nielsen, Petrine Wellendorph, Bente Frølund, Christoffer Bundgaard
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Falk-Petersen, C B, Tsonkov, T M, Nielsen, M S, Harpsøe, K, Bundgaard, C, Frølund, B, Kristiansen, U, Gloriam, D E & Wellendorph, P 2020, ' Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABA A receptors ', Scientific Reports, vol. 10, no. 1, 10078 . https://doi.org/10.1038/s41598-020-66821-0
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Falk-Petersen, C B, Tsonkov, T M, Nielsen, M S, Harpsøe, K, Bundgaard, C, Frølund, B, Kristiansen, U, Gloriam, D E & Wellendorph, P 2020, ' Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABA A receptors ', Scientific Reports, vol. 10, no. 1, 10078 . https://doi.org/10.1038/s41598-020-66821-0
Brain GABAΑ receptors are ionotropic receptors belonging to the class of Cys-loop receptors and are important drug targets for the treatment of anxiety and sleep disorders. By screening a compound library (2,112 compounds) at recombinant human α4β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3bf28828f4618689a1ced9e7f024b0d
Autor:
Kasper Harpsøe, David E. Gloriam, Gáspár Pándy-Szekeres, Andrzej J. Bojarski, Alexander S. Hauser, Tsonko M. Tsonkov, Christian Munk, Stefan Mordalski
Publikováno v:
Pándy-Szekeres, G, Munk, C, Tsonkov, T M, Mordalski, S, Harpsøe, K, Hauser, A S, Bojarski, A J & Gloriam, D E 2018, ' GPCRdb in 2018 : adding GPCR structure models and ligands ', Nucleic Acids Research, vol. 46, no. D1, gkx1109 . https://doi.org/10.1093/nar/gkx1109
Nucleic Acids Research
Nucleic Acids Research
G protein-coupled receptors are the most abundant mediators of both human signalling processes and therapeutic effects. Herein, we report GPCRome-wide homology models of unprecedented quality, and roughly 150 000 GPCR ligands with data on biological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa8cc5557332cb806bc0644cd672c9d
https://curis.ku.dk/portal/da/publications/gpcrdb-in-2018(d1933ffe-4f45-4b02-8d94-dbbe93675a46).html
https://curis.ku.dk/portal/da/publications/gpcrdb-in-2018(d1933ffe-4f45-4b02-8d94-dbbe93675a46).html
