Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Tsoka Sophia"'
Motivation: Despite advances in the computational analysis of high-throughput molecular profiling assays (e.g. transcriptomics), a dichotomy exists between methods that are simple and interpretable, and ones that are complex but with lower degree of
Externí odkaz:
http://arxiv.org/abs/2306.05813
Cancer is a complex disease with significant social and economic impact. Advancements in high-throughput molecular assays and the reduced cost for performing high-quality multi-omics measurements have fuelled insights through machine learning . Previ
Externí odkaz:
http://arxiv.org/abs/2206.10699
Autor:
Avelar, Pedro Henrique da Costa, Del Coco, Natalia, Lamb, Luis C., Tsoka, Sophia, Cardoso-Silva, Jonathan
Background: Following the outbreak of the coronavirus epidemic in early 2020, municipalities, regional governments and policymakers worldwide had to plan their Non-Pharmaceutical Interventions (NPIs) amidst a scenario of great uncertainty. At this ea
Externí odkaz:
http://arxiv.org/abs/2104.01133
Autor:
Li, Yutong, Cardoso-Silva, Jonathan, Kelly, John M., Delves, Michael J., Furnham, Nicholas, Papageorgiou, Lazaros G., Tsoka, Sophia
Publikováno v:
In Artificial Intelligence In Medicine January 2024 147
Autor:
Ainali Chrysanthi, Valeyev Najl, Perera Gayathri, Williams Andrew, Gudjonsson Johann E, Ouzounis Christos A, Nestle Frank O, Tsoka Sophia
Publikováno v:
BMC Genomics, Vol 13, Iss 1, p 472 (2012)
Abstract Background Psoriasis is an immune-mediated disease characterised by chronically elevated pro-inflammatory cytokine levels, leading to aberrant keratinocyte proliferation and differentiation. Although certain clinical phenotypes, such as plaq
Externí odkaz:
https://doaj.org/article/4d1ed675d163496d9aff48c1b9f04728
Publikováno v:
BMC Research Notes, Vol 4, Iss 1, p 462 (2011)
Abstract Background Cellular constituents such as proteins, DNA, and RNA form a complex web of interactions that regulate biochemical homeostasis and determine the dynamic cellular response to external stimuli. It follows that detailed understanding
Externí odkaz:
https://doaj.org/article/828e3435c14c4c8191d7d8f89e363bb6
Autor:
Tsoka Sophia, Hazelwood Lee, Espinosa Octavio, Freilich Shiri, Simon Michelle, Ainali Chrysanthi, Ouzounis Christos A, Hancock John M
Publikováno v:
BMC Evolutionary Biology, Vol 11, Iss 1, p 142 (2011)
Abstract Background Cellular ATP levels are generated by glucose-stimulated mitochondrial metabolism and determine metabolic responses, such as glucose-stimulated insulin secretion (GSIS) from the β-cells of pancreatic islets. We describe an analysi
Externí odkaz:
https://doaj.org/article/54b94015c71047e4aa9b632d2c97f8ad
Publikováno v:
Algorithms for Molecular Biology, Vol 5, Iss 1, p 36 (2010)
Abstract Background The detection of modules or community structure is widely used to reveal the underlying properties of complex networks in biology, as well as physical and social sciences. Since the adoption of modularity as a measure of network t
Externí odkaz:
https://doaj.org/article/1e4e056acb234411ba058ae69d3a1a1d
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 557 (2010)
Abstract Background Genome-wide expression patterns in physiological cardiac hypertrophy. Co-expression patterns in physiological cardiac hypertrophy Results In this study, the first large-scale analysis of publicly available genome-wide expression d
Externí odkaz:
https://doaj.org/article/4b406f71577e424c83dcc070f70fde7b
Autor:
Tsoka Sophia, Blanc Eric, Gottlieb Assaf, Goldovsky Leon, Freilich Shiri, Ouzounis Christos A
Publikováno v:
BMC Bioinformatics, Vol 10, Iss 1, p 355 (2009)
Abstract Background Previous methods of detecting the taxonomic origins of arbitrary sequence collections, with a significant impact to genome analysis and in particular metagenomics, have primarily focused on compositional features of genomes. The e
Externí odkaz:
https://doaj.org/article/450926a8859e4dc38b913f0bab8e3cb6