Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Tskitishvili Ov"'
Autor:
L. I. Serebryakova, Galina G. Konovalova, Irina Studneva, A. A. Timoshin, Shul'zhenko Vs, Vadim Z. Lankin, Tskitishvili Ov, Yu. A. Pelogeykina, Oleg I. Pisarenko
Publikováno v:
Molecular and Cellular Biochemistry
This study investigated the effects of peptide apelin-12 (H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH, A12) and its novel structural analog (H-(N(α)Me)Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Nle-Pro-Phe-OH, AI) on myocardial antioxidant enzyme
Autor:
Alexander A. Timoshin, Anatoly F. Vanin, I. M. Studneva, Oleg I. Pisarenko, L. I. Serebryakova, D. Yu. Drobotova, Tskitishvili Ov, Enno K. Ruuge
Publikováno v:
Biophysics. 55:999-1005
Injection of dinitrosyl iron complexes with glutathione at the onset of 40-min regional myocardial ischemia in rat was shown to exert a clear cardioprotective action by decreasing the infarct size and suppressing the cardiac rhythm disturbance. After
Autor:
L. I. Serebryakova, Alexander A. Timoshin, Oleg I. Pisarenko, D. Yu. Drobotova, Enno K. Ruuge, I. M. Studneva, Tskitishvili Ov
Publikováno v:
Biophysics. 53:313-316
Changes in nitric oxide concentration in the rat myocardium in situ during temporary occlusion of the anterior descending coronary artery and subsequent reperfusion were monitored by microdialysis in the risk zone and a normal zone, using an NO trap
Publikováno v:
Bulletin of Experimental Biology and Medicine. 141:296-298
The possibility of decreasing the degree of irreversible alterations in cardiomyocytes with original saline reperfusion solution enriched with L-aspartic acid, D-glucose, and D-mannitol was studied on experimental rats with regional ischemia and repe
Publikováno v:
Journal of Cardiovascular Pharmacology. 25:564-571
With microdialysis, we monitored cardiac interstitial fluid (ISF) levels of allopurinol, its metabolites, and the adenine nucleotide breakdown products (ANBP), inosine, hypoxanthine (HYP), xanthine (Xa), uric acid (UA) in dogs that received 1 and 10
Autor:
Maria Sidorova, Oleg I. Pisarenko, Zh. D. Bespalova, Pal'keeva Me, Irina Studneva, Yu. A. Pelogeykina, Denis N. Khatri, A. A. Az’muko, Tskitishvili Ov, L. I. Serebryakova
Publikováno v:
Bulletin of experimental biology and medicine. 152(1)
Apelin-12 (A-12) peptide was synthesized by automated solid phase method and purified by reverse phase HPLC. Its homogeneity and structure were confirmed by HPLC, (1)H-NMR spectroscopy, and mass spectroscopy. Acute myocardial infarction was induced b
Autor:
Oleg I. Pisarenko, Pal'keeva Me, L. I. Serebryakova, Maria Sidorova, Irina Studneva, Tskitishvili Ov, Yu. A. Pelogeykina, A. S. Molokoedov, Zh. D. Bespalova, Denis N. Khatri, A. A. Az’muko
Publikováno v:
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. 443
Autor:
Alexander A. Timoshin, Kuz'min Ai, Medvedev Os, Tskitishvili Ov, L. I. Serebryakova, Enno K. Ruuge
Publikováno v:
Experientia. 50:677-679
A new experimental approach for spin-trapping of oxygen radicals in a selected region of the heart in situ is described. This approach is based on microdialysis, and it permits the detection of oxygen radicals in conditions of local ischemia and rest
Autor:
L. I. Serebryakova, D. Yu. Drobotova, Alexander A. Timoshin, Vladimir L. Lakomkin, Anatoly F. Vanin, Tskitishvili Ov
Publikováno v:
Journal of Hypertension. 29:e319-e320
Autor:
A. S. Molokoedov, Maria E Pal'keeva, L. I. Serebryakova, Tskitishvili Ov, Andrei A Az'muko, Zhanna D. Bespalova, Denis N. Khatri, Oleg I. Pisarenko, Irina Studneva, Maria Sidorova, Yulia A. Pelogeykina
Publikováno v:
Journal of Pharmacology & Pharmacotherapeutics
Objective: To examine cardioprotective effects of Ρ-terminal fragment of adipokine apelin-12 (A12), its novel structural analogue [MeArg 1 , NLe 10 ]-A12 (I), and [d-Ala 12 ]-A12 (II), a putative antagonist of APJ receptor, employing in vivo model o