Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tsipora Malachi"'
Autor:
Anat Gafter-Gvili, Boris Zingerman, Benaya Rozen-Zvi, Yaacov Ori, Hefziba Green, Ido Lubin, Tsipora Malachi, Uzi Gafter, Michal Herman-Edelstein
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68341 (2013)
BACKGROUND:DNA repair is a cellular defence mechanism responding to DNA damage caused in large part by oxidative stress. There is a controversy with regard to the effect of red blood cells on DNA damage and cellular response. AIM:To investigate the e
Externí odkaz:
https://doaj.org/article/540c121bc35143089b0e8318f9bca3a0
Autor:
Shelly Lichtenberg, Tsipora Malachi, Uzi Gafter, Benaya Rozen-Zvi, Boris Zingerman, Michal Herman-Edelstein, Yaacov Ori
Publikováno v:
Biomedicine & Pharmacotherapy. 66:111-115
Introduction Cancer is a major cause of mortality among transplant recipients. Immunosuppressive treatment is a modifiable factor contributing to this phenomenon. Cyclosporine in kidney transplant recipients was associated with reduced UV-induced DNA
Autor:
Yaacov Ori, Anat Gafter-Gvili, Benaya Rozen-Zvi, Asher Korzets, Avry Chagnac, Michal Herman, Tsipora Malachi, Uzi Gafter, Boris Zingerman
Publikováno v:
Leukemia Research. 35:219-225
Background Mitochondria provide ATP and Ca 2+ needed for DNA repair, but also produce reactive oxygen species (ROS), which may damage DNA. Aim To investigate the effect of mitochondrial function inhibition on DNA repair. Method Five mitochondrial inh
Publikováno v:
Biochemical and Biophysical Research Communications. 336:842-846
Spontaneous DNA repair in peripheral blood mononuclear cells (PBMC) has been recently described. The aim of this study was to evaluate whether spontaneous DNA repair is Ca2+-dependent, as in vitro-stimulated DNA repair. Spontaneous DNA repair in PBMC
Autor:
Tsipora Malachi, Talia Weinstein, Uzi Gafter, Dina Zevin, Yaacov Ori, Avry Chagnac, Gai Milo, Michal Herman
Publikováno v:
Biochemical and Biophysical Research Communications. 320:578-586
DNA molecules are constantly damaged during mitosis and by oxygen-free radicals produced by either cellular metabolism or by external factors. Populations at risk include patients with cancer-prone disease, patients under enhanced oxidative stress, a
Autor:
Avry Chagnac, Uzi Gafter, Dina Zevin, Tsipora Malachi, Talia Weinstein, Yaacov Ori, Michal Herman, Asher Korzets
Publikováno v:
Journal of Laboratory and Clinical Medicine. 140:255-262
Treatment with cyclosporin A (CsA) in kidney-transplant recipients is associated with reduced DNA repair and enhanced cancer incidence. CsA is an inhibitor of the serine/threonine phosphatase calcineurin, also termed PP2B, which is a Ca2+/calmodulin-
Autor:
Avry Chagnac, Dina Zevin, Asher Korzets, Yaacov Ori, Michal Herman, Uzi Gafter, Tsipora Malachi, Talia Weinstein
Publikováno v:
Journal of Laboratory and Clinical Medicine. 137:14-20
Cancer incidence is enhanced in transplant recipients. Decreased DNA repair ability is associated with increased cancer incidence. Transplanted patients with cancer were found to have reduced DNA repair. We hypothesized that immunosuppressive therapy
Autor:
Tsipora Malachi, Mona Boaz, Uzi Gafter, Talia Weinstein, Michal Herman, Avry Chagnac, Yaacov Ori, Asher Korzets
Publikováno v:
Nephrology Dialysis Transplantation. 15:883-887
Uraemic patients have a decreased ability to withstand oxidative stress. It is postulated that their antioxidant capacity is reduced, yet the mechanism remains unclear. Recently 33 haemodialysis (HD) patients were exposed to chloramine contamination
Publikováno v:
Journal of Laboratory and Clinical Medicine. 133:391-400
Lymphocytes from patients with end-stage renal disease (ESRD) exhibit elevated cytosolic calcium concentration ([Ca2+]i), but the mechanisms responsible for this elevated [Ca2+]i have not been entirely elucidated. In addition, lymphocyte proliferativ
Autor:
Uzi Gafter, Hefziba Green, Tsipora Malachi, Boris Zingerman, Ido Lubin, Anat Gafter-Gvili, Benaya Rozen-Zvi, Michal Herman-Edelstein, Yaacov Ori
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68341 (2013)
PLoS ONE
PLoS ONE
Background DNA repair is a cellular defence mechanism responding to DNA damage caused in large part by oxidative stress. There is a controversy with regard to the effect of red blood cells on DNA damage and cellular response. Aim To investigate the e