Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Tsion E. Abraham"'
Publikováno v:
Cells, Vol 13, Iss 20, p 1693 (2024)
The androgen receptor (AR), a member of the nuclear steroid hormone receptor family of transcription factors, plays a crucial role not only in the development of the male phenotype but also in the development and growth of prostate cancer. While AR s
Externí odkaz:
https://doaj.org/article/114d2f84ea904314806481cc2398bfd4
Autor:
Karin Legerstee, Jason Sueters, Tsion E. Abraham, Johan A. Slotman, Gert-Jan Kremers, Jacob P. Hoogenboom, Adriaan B. Houtsmuller
Publikováno v:
Biology Open, Vol 11, Iss 11 (2022)
Externí odkaz:
https://doaj.org/article/0442c45b12564bca8f692c82b784d27d
Autor:
Karin Legerstee, Tsion E. Abraham, Wiggert A. van Cappellen, Alex L. Nigg, Johan A. Slotman, Adriaan B. Houtsmuller
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Focal adhesions (FAs) are flat elongated structures that mediate cell migration and link the cytoskeleton to the extracellular matrix. Along the vertical axis FAs were shown to be composed of three layers. We used structured illumination mic
Externí odkaz:
https://doaj.org/article/04042c18fbe1426ea391cb28c528894f
Autor:
Tamara Hoppenbrouwers, Andi R. Sultan, Tsion E. Abraham, Nicole A. Lemmens-den Toom, Silvie Hansenová Maňásková, Wiggert A. van Cappellen, Adriaan B. Houtsmuller, Willem J. B. van Wamel, Moniek P. M. de Maat, Johan W. van Neck
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Staphylococcus aureus are strong inducers of neutrophil extracellular traps (NETs), a defense mechanism of neutrophils against pathogens. Our aim was to explore the role of Protein A in S. aureus-induced NETosis. We determined the Protein A productio
Externí odkaz:
https://doaj.org/article/f4475e7b910646f4839b0bfbaae80543
Autor:
Guzman Torrelo, Tsion E Abraham, Frank Bruchertseifer, Robin M. de Kruijff, Dik C. van Gent, Martin E. van Royen, Adriaan B Houtsmuller, Thomas A Hartjes, Roland Kanaar, Antonia G. Denkova, Jeroen Essers, Alfred Morgenstern, Johan A. Slotman, Stefan J. Roobol
Publikováno v:
Nanotheranostics, 4, 14-25. Ivyspring International Publishers
Nanotheranostics, 4(1)
Nanotheranostics
Nanotheranostics, 4(1)
Nanotheranostics
Polymersomes have the potential to be applied in targeted alpha radionuclide therapy, while in addition preventing release of recoiling daughter isotopes. In this study, we investigated the cellular uptake, post uptake processing and intracellular lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3301213e373015dce1554d9de6b40fb5
https://pure.eur.nl/en/publications/3c1aced6-5bf4-4935-bd62-bbc3cb2f5b60
https://pure.eur.nl/en/publications/3c1aced6-5bf4-4935-bd62-bbc3cb2f5b60
Autor:
Fatma Özgün, Martin E. van Royen, Adriaan B Houtsmuller, Tsion E Abraham, Nathan A. Lack, Bart Geverts, Zeynep Kaya, Tunç Morova
Publikováno v:
Journal of Cell Science, 134(14):jcs258332. Company of Biologists Ltd
Androgen receptor (AR) splice variants are proposed to be a potential driver of lethal castration-resistant prostate cancer. AR splice variant 7 (ARv7) is the most commonly observed isoform and strongly correlates with resistance to second-generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d538a977b3d5a4df03aec74f1922b9
https://pure.eur.nl/en/publications/69dc424f-d8cf-4a7c-a2c6-396aa466a620
https://pure.eur.nl/en/publications/69dc424f-d8cf-4a7c-a2c6-396aa466a620
Autor:
Johan A. Slotman, Tsion E Abraham, Wiggert A. van Cappellen, Adriaan B. Houtsmuller, Karin Legerstee, Alex L. Nigg
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, 11(1):2315. Nature Publishing Group
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, 11(1):2315. Nature Publishing Group
Focal adhesions (FAs) are flat elongated structures that mediate cell migration and link the cytoskeleton to the extracellular matrix. Along the vertical axis FAs were shown to be composed of three layers. We used structured illumination microscopy t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac43cdbfbb43afec40c1519698e6a86
https://doi.org/10.1038/s41598-021-81898-x
https://doi.org/10.1038/s41598-021-81898-x
Autor:
Irene van den Bent, Adriaan B Houtsmuller, Wiggert A. van Cappellen, Tsion E Abraham, Maarten W. Paul, Jeroen Essers, Stefan J. Roobol, Dik C. van Gent, Roland Kanaar
Publikováno v:
International Journal of Molecular Sciences, 21(18):6602, 1-19. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Volume 21
Issue 18
International Journal of Molecular Sciences, Vol 21, Iss 6602, p 6602 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 18
International Journal of Molecular Sciences, Vol 21, Iss 6602, p 6602 (2020)
High-linear-energy-transfer (LET) radiation is more lethal than similar doses of low-LET radiation types, probably a result of the condensed energy deposition pattern of high-LET radiation. Here, we compare high-LET &alpha
particle to low-LET X-
particle to low-LET X-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eeb70e6b74c7ac70930b646da0ac4d9
https://pure.eur.nl/en/publications/b64b85c6-8904-40f1-9390-833daceff4cf
https://pure.eur.nl/en/publications/b64b85c6-8904-40f1-9390-833daceff4cf
Autor:
Daniela Roell, Sophie Bartsch, Tsion E Abraham, Martin E. van Royen, Rudolf Matusch, Wiebke Hessenkemper, Florian Kraft, Aria Baniahmad, Adriaan B. Houtsmuller, Monique Hauschild, Thomas W. Rösler
Publikováno v:
Journal of Steroid Biochemistry and Molecular Biology, 188, 59-70. Elsevier Ltd.
Androgen receptor (AR) antagonists are used for hormone therapy of prostate cancer (PCa). However resistance to the treatment occurs eventually. One possible reason is the occurrence of AR mutations that prevent inhibition of AR-mediated transactivat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4909148b01de07369373540b26b7716
https://pure.eur.nl/en/publications/b533bb5a-9c2e-45c8-888c-549ecd9d7f2e
https://pure.eur.nl/en/publications/b533bb5a-9c2e-45c8-888c-549ecd9d7f2e
Autor:
Tsion E Abraham, Wiebke Hessenkemper, Athanassios Giannis, Daniela Roell, Martin E. van Royen, Sophie Bartsch, Aria Baniahmad, Florian Kraft, Adriaan B. Houtsmuller, Marie Thiele, SM Rabe
Publikováno v:
Current Medicinal Chemistry, 22(9), 1156-1167. Bentham Science Publishers B.V.
The prostate adenocarcinoma is the cancer with the highest incidence for men in Western countries. Targeting the androgen receptor (AR) by antagonists is used as hormone therapy for prostate cancer (PCa), however, eventually therapy resistance occurs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710bf0d7a081411fde7833b26ea466c5
https://doi.org/10.2174/0929867321666140601164240
https://doi.org/10.2174/0929867321666140601164240