The structure of NAD ⁺ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.

Autor: Klontz E; Division of Vaccine Research, Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, USA., Obi JO; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland, USA., Wang Y; Division of Vaccine Research, Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, USA; Department of Physiology, School of Basic Medical Sciences and Clinical Pharmacy, China Pharmaceutical University, Nanjing, P.R. China., Glendening G; Division of Vaccine Research, Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, USA., Carr J; Division of Vaccine Research, Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, USA., Tsibouris C; Division of Vaccine Research, Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, USA., Buddula S; Division of Vaccine Research, Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, USA., Nallar S; Division of Vaccine Research, Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, USA; Department of Microbiology and Immunology, School of Medicine, University of Maryland, Baltimore, Maryland, USA., Soares AS; Brookhaven National Laboratory, National Synchrotron Light Source II, Structural Biology Program, Upton, New York, USA., Beckett D; Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland, USA., Redzic JS; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Denver, School of Medicine, Aurora, Colorado, USA., Eisenmesser E; Department of Biochemistry and Molecular Genetics, School of Medicine, University of Colorado Denver, School of Medicine, Aurora, Colorado, USA., Palm C; Department of Biological Sciences, Towson University, Towson, Maryland, USA., Schmidt K; Department of Biological Sciences, Towson University, Towson, Maryland, USA., Scudder AH; Department of Biological Sciences, Towson University, Towson, Maryland, USA., Obiorah T; Department of Biological Sciences, Towson University, Towson, Maryland, USA., Essuman K; Department of Developmental Biology, Washington University School of Medicine, St Louis, Missouri, USA; Department of Neurosurgery, Massachusetts General Hospital, Boston, Massachusetts, USA., Milbrandt J; Department of Developmental Biology, Washington University School of Medicine, St Louis, Missouri, USA., Diantonio A; Department of Developmental Biology, Washington University School of Medicine, St Louis, Missouri, USA., Ray K; Division of Vaccine Research, Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, USA; Department of Biochemistry and Molecular Biology at the University of Maryland, School of Medicine, Baltimore, Maryland, USA., Snyder MLD; Department of Biological Sciences, Towson University, Towson, Maryland, USA., Deredge D; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland, USA., Snyder GA; Division of Vaccine Research, Institute of Human Virology, School of Medicine, University of Maryland, Baltimore, Maryland, USA; Department of Microbiology and Immunology, School of Medicine, University of Maryland, Baltimore, Maryland, USA. Electronic address: gsnyder@ihv.umaryland.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2023 Nov; Vol. 299 (11), pp. 105290. Date of Electronic Publication: 2023 Sep 25.