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AMBRA1 levels predict resistance to MAPK inhibitors in melanoma.

Autor: Di Leo L; Melanoma Research Team, Center for Autophagy, Recycling and Disease, Danish Cancer Institute, Copenhagen 2100, Denmark., Pagliuca C; Melanoma Research Team, Center for Autophagy, Recycling and Disease, Danish Cancer Institute, Copenhagen 2100, Denmark., Kishk A; Department of Life Sciences and Medicine, University of Luxembourg, Belvaux 4365, Luxembourg., Rizza S; Redox Biology Group, Danish Cancer Institute, Copenhagen 2100, Denmark., Tsiavou C; Melanoma Research Team, Center for Autophagy, Recycling and Disease, Danish Cancer Institute, Copenhagen 2100, Denmark., Pecorari C; Redox Biology Group, Danish Cancer Institute, Copenhagen 2100, Denmark., Dahl C; Molecular Diagnostics Group, Danish Cancer Institute, Copenhagen 2100, Denmark., Pacheco MP; Department of Life Sciences and Medicine, University of Luxembourg, Belvaux 4365, Luxembourg., Tholstrup R; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark., Brewer JR; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark., Berico P; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016., Hernando E; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016., Cecconi F; Cell Stress and Survival, Center for Autophagy, Recycling and Disease, Danish Cancer Institute, Copenhagen 2100, Denmark.; Faculty of Medicine and Surgery, Università Cattolica del 'Sacro Cuore', Fondazione Policlinico Gemelli-Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome 00136, Italy., Ballotti R; Université Côte d'Azur, Nice 06200, France.; Inserm, Biology and Pathologies of melanocytes, team1, Equipe labellisée Ligue 2020, Centre Méditerranéen de Médecine Moléculaire, Nice 06200, France., Bertolotto C; Université Côte d'Azur, Nice 06200, France.; Inserm, Biology and Pathologies of melanocytes, team1, Equipe labellisée Ligue 2020, Centre Méditerranéen de Médecine Moléculaire, Nice 06200, France., Filomeni G; Redox Biology Group, Danish Cancer Institute, Copenhagen 2100, Denmark., Gjerstorff MF; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense 5230, Denmark.; Department of Oncology, Odense University Hospital, Odense 5000, Denmark., Sauter T; Department of Life Sciences and Medicine, University of Luxembourg, Belvaux 4365, Luxembourg., Lovat P; Translational and Clinical Research Institute, Medical School, Newcastle University, Newcastle upon Tyne NE2 4HH, United Kingdom., Guldberg P; Molecular Diagnostics Group, Danish Cancer Institute, Copenhagen 2100, Denmark.; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense 5230, Denmark., De Zio D; Melanoma Research Team, Center for Autophagy, Recycling and Disease, Danish Cancer Institute, Copenhagen 2100, Denmark.; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense 5230, Denmark.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Jun 18; Vol. 121 (25), pp. e2400566121. Date of Electronic Publication: 2024 Jun 13.