Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Tseten Yeshi"'
Autor:
Yash Agarwal, Cole Beatty, Sara Ho, Lance Thurlow, Antu Das, Samantha Kelly, Isabella Castronova, Rajeev Salunke, Shivkumar Biradar, Tseten Yeshi, Anthony Richardson, Moses Bility
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/406f197c4a954537bb5ac4d42ad0861e
Autor:
Lance R. Thurlow, Anthony R. Richardson, Moses T. Bility, Tseten Yeshi, Antu Das, Rajeev Salunke, Yash Agarwal, Isabella Castronova, Sara Ho, Cole Beatty, Samantha Kelly, Shivkumar Biradar
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Autor:
Jack Crawford, Goutham Narla, Jaya Sangodkar, Kameswaran Ravichandran, Eric M. Ostertag, Analisa DiFeo, Sahar Mazhar, Angela Arey, Tseten Yeshi Jamling, Min Tong, Fallon K. Noto, Valeriya Adjan-Steffey, Wei Zhang, Christopher B. McClain
Publikováno v:
Molecular Cancer Therapeutics. 17:2481-2489
The rat is the preferred model for toxicology studies, and it offers distinctive advantages over the mouse as a preclinical research model including larger sample size collection, lower rates of drug clearance, and relative ease of surgical manipulat
Autor:
Sara Ho, Antu Das, Yash Agarwal, Anthony R. Richardson, Isabella Castronova, Shivkumar Biradar, Samantha Kelly, Tseten Yeshi, Rajeev Salunke, Moses T. Bility, Lance R. Thurlow, Cole Beatty
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
The human skin is a major barrier for host defense against many human pathogens, with several pathogens directly targeting the skin for replication and disease. The skin is also the primary route of infection for a myriad of vector-borne diseases; th
Autor:
Jaya Sangodkar, Rita Tohme, Sam Moody, Matthew D. Galsky, Analisa DiFeo, Marwan K. Tayeh, B. Mark Evers, Fallon K. Noto, Caitlin M. O’Connor, Bisoye Towobola Adedeji, Ming Tong, Tseten Yeshi Jamling, Kajari Bhattacharya, Lauren Hurst, Goutham Narla, Sudeh Izadmehr, Jyothsna Narla, Eric M. Ostertag, Amit R. Rupani, Christopher B. McClain, Xiaohua Gao, Jack Crawford, Jeffrey W. Innis, Erika Hanson, Kristin LeSueur
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0240169 (2020)
PLoS ONE, Vol 15, Iss 10, p e0240169 (2020)
We have created the immunodeficient SRG rat, a Sprague-Dawley Rag2/Il2rg double knockout that lacks mature B cells, T cells, and circulating NK cells. This model has been tested and validated for use in oncology (SRG OncoRat®). The SRG rat demonstra
Autor:
Antu Das, Yash Argawal, Tseten Yeshi Jamling, Bisoye Towobola Adedeji, Fallon K. Noto, Moses T. Bility, Rajeev Salunke, Sara Grace Ho, Cole Beatty
Publikováno v:
Cancer Research. 80:5621-5621
The development of Novel cancer immunotherapies has relied on the use of immune humanized mice. The field of study can be enhanced using an immune humanized rat, which will provide several advantages over the currently available humanized mouse model
Autor:
Noto K. Fallon, Sam Moody, Goutham Narla, Bisoye Towobola Adedeji, Valeriya Steffey, Tseten Yeshi Jamling, Jack Crawford, Chris Brenzel
Publikováno v:
Cancer Research. 80:6133-6133
The use of the most predictive model is essential in transferring scientific knowledge from bench to bedside. In In vivo cancer research, immunodeficient mice models are being used, but have been found with limitations. They fall short in tumor take
Autor:
Sara Ho, Antu Das, Rajeev Salunke, Fallon K. Noto, Bisoye Towobola Adedeji, Yash Agarwal, Moses T. Bility, Cole Beatty, Tseten Yeshi Jamling
Publikováno v:
Molecular Cancer Therapeutics. 18:A007-A007
Immune humanized mice have been valuable in the development of novel cancer immunotherapies and have demonstrated stronger efficacy when combined with standard of care chemotherapy. An immune humanized rat could provide several advantages over the cu
Autor:
Fallon K. Noto, Sam Moody, Bisoye Towobola Adedeji, Tseten Yeshi Jamling, Jack Crawford, B. Mark Evers, Goutham Narla, Chris Brenzel
Publikováno v:
Molecular Cancer Therapeutics. 18:B067-B067
Current cell line-derived cancer and PDX mouse models are hindered by low engraftment rates and slow tumor growth kinetics. Furthermore, serial passaging of patient derived tissue results in changes to the genomic landscape such that the transplanted