Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Tsepo L. Tsekoa"'
Autor:
Varsha Chhiba, Priyen Pillay, Sibongile Mtimka, Ghaneshree Moonsamy, Lusisizwe Kwezi, Ofentse J. Pooe, Tsepo L. Tsekoa
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16723- (2023)
The unique metagenomic, metaviromic libraries and indigenous micro diversity within Southern Africa have the potential for global beneficiation in academia and industry. Microorganisms that flourish at high temperatures, adverse pH conditions, and hi
Externí odkaz:
https://doaj.org/article/cb61b6b8322b478db13ef82bafe38522
Autor:
Jennifer C. Van Wyk, B. Trevor Sewell, Michael J. Danson, Tsepo L. Tsekoa, Muhammed F. Sayed, Don A. Cowan
Publikováno v:
Current Research in Structural Biology, Vol 4, Iss , Pp 256-270 (2022)
Nitrile hydratases (NHases) are important biocatalysts for the enzymatic conversion of nitriles to industrially-important amides such as acrylamide and nicotinamide. Although thermostability in this enzyme class is generally low, there is not suffici
Externí odkaz:
https://doaj.org/article/c90cb24114fc4f7986852852b84aaf3f
Autor:
Advaita Acarya Singh, Priyen Pillay, Previn Naicker, Kabamba Alexandre, Kanyane Malatji, Lukas Mach, Herta Steinkellner, Juan Vorster, Rachel Chikwamba, Tsepo L. Tsekoa
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
The hypersensitive response is elicited by Agrobacterium infiltration of Nicotiana benthamiana, including the induction and accumulation of pathogenesis-related proteins, such as proteases. This includes the induction of the expression of several cys
Externí odkaz:
https://doaj.org/article/cfd344e9e899400299b598eb5312238e
Autor:
Daria A. Rutkowska, Nobalanda B. Mokoena, Tsepo L. Tsekoa, Vusi S. Dibakwane, Martha M. O’Kennedy
Publikováno v:
BMC Veterinary Research, Vol 15, Iss 1, Pp 1-15 (2019)
Abstract Background African horse sickness (AHS) is a severe arthropod-borne viral disease of equids, with a mortality rate of up to 95% in susceptible naïve horses. Due to safety concerns with the current live, attenuated AHS vaccine, alternate saf
Externí odkaz:
https://doaj.org/article/c446a926d5814dd4bcfb0f026b2c60b6
Autor:
Isak Gerber, Rachel Chikwamba, Stoyan Stoychev, Tsepo L. Tsekoa, Jinal Bhiman, Lukas Mach, Kabamba Alexandra, Lusisizwe Kwezi, Herta Steinkellner, Advaita Acarya Singh, Kevin J. Whaley, Larry Zeitlin, Michael H. Pauly, Juan Vorster, Ofentse Jacob Pooe, Lynn Morris, Therese Lotter-Stark
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Broadly neutralising antibodies (bNAbs) against human immunodeficiency virus type 1 (HIV-1), such as CAP256-VRC26 are being developed for HIV prevention and treatment. These Abs carry a unique but crucial post-translational modification (PTM), namely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b19686c642bd96196e5cfdf45a61d39
http://link.springer.com/article/10.1038/s41598-020-63052-1
http://link.springer.com/article/10.1038/s41598-020-63052-1
Publikováno v:
Current Opinion in Biotechnology. 61:89-95
Local manufacturing of protein-based vaccines and therapies in Africa is limited and contributes to a trade deficit, security of supply concerns and poor access to biopharmaceuticals by the poor. Plant molecular farming is a potential technology solu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c241405f5ebc1cf1d0bc66fccc69d69d
https://doi.org/10.1016/j.copbio.2019.11.005
https://doi.org/10.1016/j.copbio.2019.11.005
Publikováno v:
Vaccines, Vol 9, Iss 1270, p 1270 (2021)
Vaccines
Vaccines
Since the demonstration of the first plant-produced proteins of medical interest, there has been significant growth and interest in the field of plant molecular farming, with plants now being considered a viable production platform for vaccines. Desp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cb766b0957dd904b71a88e814bb0f1f
https://www.mdpi.com/2076-393X/9/11/1270
https://www.mdpi.com/2076-393X/9/11/1270
Publikováno v:
Molecular Biology Reports. 47:353-361
Endonucleases play a crucial role as reagents in laboratory research and diagnostics. Here, metagenomics was used to functionally screen a fosmid library for endonucleases. A fosmid library was constructed using metagenomic DNA isolated from soil sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d9dc13698314aa3fb3cd37edbe5f4f
https://doi.org/10.1007/s11033-019-05137-3
https://doi.org/10.1007/s11033-019-05137-3
Publikováno v:
Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie. :26-40
Met die toenemende voorkoms van weerstandige Plasmodium stamme het die beheer van malaria-voorkoms en -mortaliteit weer op die voorgrond getree. Nuwe teikens en antimalariamiddels wat effektief is teen weerstandige malaria-parasiete word dus dringend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9496743eb56a30cb745ed006e3c0186f
https://doi.org/10.36303/satnt.2019.38.1.677
https://doi.org/10.36303/satnt.2019.38.1.677
Autor:
Sindisiwe G. Buthelezi, Stoyan Stoychev, Tsepo L. Tsekoa, Michael Crampton, Sipho Mamputha, Robyn Roth, P. van Zyl
Publikováno v:
Journal of Applied Microbiology. 122:1402-1411
Aims To investigate the production of soluble Cross-Reacting Material 197 (CRM197) in Escherichia coli, a safe and effective T-cell dependent protein carrier for polysaccharides used in the manufacture and application of multivalent conjugate vaccine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16f7fb4ad89b4b94aedc8f3e67af3eb3
https://doi.org/10.1111/jam.13441
https://doi.org/10.1111/jam.13441