Drp1/p53 interaction mediates p53 mitochondrial localization and dysfunction in septic cardiomyopathy.

Autor: Mukherjee R; Department of Pediatrics, Division of Critical Care Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Tetri LH; Department of Pediatrics, Division of Critical Care Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Anesthesia, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Li SJ; Department of Pediatrics, Division of Critical Care Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Fajardo G; Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA., Ostberg NP; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Tsegay KB; Department of Pediatrics, Division of Critical Care Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Gera K; Department of Pediatrics, Division of Critical Care Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Cornell TT; Department of Pediatrics, Division of Critical Care Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Bernstein D; Department of Pediatrics, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA., Mochly-Rosen D; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA., Haileselassie B; Department of Pediatrics, Division of Critical Care Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Chemical and Systems Biology, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: bhailes3@stanford.edu.

Publikováno v: Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2023 Apr; Vol. 177, pp. 28-37. Date of Electronic Publication: 2023 Feb 24.

A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2.

Autor: Tsegay KB; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States., Adeyemi CM; St. Louis University School of Medicine, Department of Pharmacology and Physiology, St. Louis, MO, United States., Gniffke EP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States., Sather DN; Center for Global Infectious Disease Research, Seattle Children's Research Institute, Seattle, WA, United States.; Department of Pediatrics, University of Washington, Seattle, WA, United States., Walker JK; St. Louis University School of Medicine, Department of Pharmacology and Physiology, St. Louis, MO, United States.; Henry and Amelia Nasrallah Center for Neuroscience, Saint Louis University St. Louis, Seattle, WA, United States., Smith SEP; Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, United States.; Department of Pediatrics, University of Washington, Seattle, WA, United States.; Graduate Program in Neuroscience, University of Washington, Seattle, WA, United States.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2021 Jun 14; Vol. 12, pp. 685308. Date of Electronic Publication: 2021 Jun 14 (Print Publication: 2021).