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Akademický článek

Clinical and radiological effect of medialized cortical bone trajectory for lumbar pedicle screw fixation in patients with degenerative lumbar spondylolisthesis: study protocol for a randomized controlled trial (mPACT)

Autor: Anja Tschugg, Pujan Kavakebi, Sebastian Hartmann, Sara Lener, Christoph Wipplinger, Wolfgang N. Löscher, Sabrina Neururer, Matthias Wildauer, Claudius Thomé

Publikováno v: Trials, Vol 19, Iss 1, Pp 1-8 (2018)

Abstract Background Spinal fusion with pedicle screw fixation represents the gold standard for lumbar degenerative disc disease with instability. Although it is an established technique, it is nevertheless an invasive intervention with high complicat

Externí odkaz: https://doaj.org/article/4722b6dad9cc447a8085252d1455b97a

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Akademický článek

The influence of surface EMG-triggered multichannel electrical stimulation on sensomotoric recovery in patients with lumbar disc herniation: study protocol for a randomized controlled trial (RECO)

Autor: Sara Lener, Christoph Wipplinger, Sebastian Hartmann, Wolfgang N. Löscher, Sabrina Neururer, Matthias Wildauer, Claudius Thomé, Anja Tschugg

Publikováno v: Trials, Vol 18, Iss 1, Pp 1-7 (2017)

Abstract Background Intervertebral disc degeneration is one of the most common reasons for chronic low back pain and sensomotoric deficits, often treated by lumbar sequestrectomy. Nevertheless, the prognostic factors relevant for time and quality of

Externí odkaz: https://doaj.org/article/e8242187d2904fb0a7f2d8fe60b65776

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Akademický článek

Self-complementary adeno-associated virus serotype 6 mediated knockdown of ADAMTS4 induces long-term and effective enhancement of aggrecan in degenerative human nucleus pulposus cells: A new therapeutic approach for intervertebral disc disorders.

Autor: Demissew Shenegelegn Mern, Anja Tschugg, Sebastian Hartmann, Claudius Thomé

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0172181 (2017)

Inhibition of intervertebral disc (IVD) degeneration, which is often accompanied by painful inflammatory and immunopathological processes, is challenging. Current IVD gene therapeutic approaches are based on adenoviral gene delivery systems, which ar

Externí odkaz: https://doaj.org/article/55275cbd548a4474be8978d61fed91d6

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Gender-Specific Differences in Presentation and Management of Spinal Infection: A Single-Center Retrospective Study of 159 Cases

Autor: Claudius Thomé, Sara Lener, Christoph Wipplinger, Sebastian Hartmann, Anja Tschugg, Andreas Rietzler

Publikováno v: Global Spine Journal

Study Design: A retrospective single-center analysis of 159 cases. Objective: To investigate differences between male and female patients, as spinal infection (SI) represents a life-threatening condition and numerous factors may facilitate the course

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ca58754e3bf51010e261a8fb4c4be1f
https://doi.org/10.1177/2192568220905804

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The impact of obesity and smoking on young individuals suffering from lumbar disc herniation: a retrospective analysis of 97 cases

Autor: Sebastian Hartmann, Anja Tschugg, Christoph Wipplinger, Claudius Thomé, Sara Lener

Publikováno v: Neurosurgical Review

The negative impact on spinal diseases may apply not only to obesity but also to smoking. To investigate the influence of obesity and smoking on the development and recovery of lumbar disc herniation in young adults. Retrospective analysis of 97 pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0927faabd3a508fb8721bb36ca7051
https://doi.org/10.1007/s10143-019-01151-y

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Assessment of the Retina of Plp-α-Syn Mice as a Model for Studying Synuclein-Dependent Diseases

Autor: Kaehler, Kathrin, Seitter, Hartwig, Sandbichler, Adolf M., Tschugg, Bettina, Obermair, Gerald J., Stefanova, Nadia, Koschak, Alexandra

Publikováno v: Investigative Ophthalmology & Visual Science

Purpose Synucleinopathies such as multiple system atrophy (MSA) and Parkinson's disease are associated with a variety of visual symptoms. Functional and morphological retinal aberrations are therefore supposed to be valuable biomarkers for these neur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a44e61b404018e468d12c0aaf43d22df
http://europepmc.org/articles/PMC7415298

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Extraforaminal Lumbar Disk Herniations Lead To Neuroplastic Changes: a Study Using Quantitative Sensory Testing

Autor: Valentin Fink, Wolfgang Löscher, Claudius Thomé, Sebastian Hartmann, Sara Lener, Anja Tschugg, Matthias Wildauer, Sabrina Neururer

Publikováno v: Muscle & Nerve. 58:676-680

Introduction Extraforaminal lumbar disk herniations are characterized by distinct clinical features in comparison to paramedian lumbar disk herniations. Methods We applied the quantitative sensory testing (QST) protocol of the German Research Network

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2845bc5aebcf35254fa69a94712cebe9
https://doi.org/10.1002/mus.26184

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Management of spinal infection: a review of the literature

Autor: Anja Tschugg, Sebastian Hartmann, Claudius Thomé, Sara Lener, Francesco Certo, Giuseppe Barbagallo

Publikováno v: Acta Neurochirurgica

Spinal infection (SI) is defined as an infectious disease affecting the vertebral body, the intervertebral disc, and/or adjacent paraspinal tissue and represents 2–7% of all musculoskeletal infections. There are numerous factors, which may facilita

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab0d7cfaa58724d906cd1df74e5ff92
https://doi.org/10.1007/s00701-018-3467-2

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