Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Tsan-Zon Liu"'
Publikováno v:
Tumor Biology, Vol 39 (2017)
We provide herein several lines of evidence to substantiate that folic acid (or folate) is a micronutrient capable of functioning as a novel redox regulator on hepatocellular carcinoma. First, we uncovered that folate deficiency could profoundly down
Externí odkaz:
https://doaj.org/article/b39d53f84ebd43feaf4caab948316ffa
Autor:
Hung-Chih Hsu, Wen-Ming Chang, Jin-Yi Wu, Chin-Chin Huang, Fung-Jou Lu, Yi-Wen Chuang, Pey-Jium Chang, Kai-Hua Chen, Chang-Zern Hong, Rang-Hui Yeh, Tsan-Zon Liu, Ching-Hsein Chen
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146440 (2016)
Despite a plethora of literature has documented that osteoarthritis (OA) is veritably associated with oxidative stress-mediated chondrocyte death and matrix degradation, yet the possible involvement of synoviocyte abnormality as causative factor of O
Externí odkaz:
https://doaj.org/article/592339e572f44884a01d590f484a6b8b
Publikováno v:
Journal of the Formosan Medical Association, Vol 109, Iss 2, Pp 106-112 (2010)
Betel quid (BQ) chewing is a popular oral masticatory activity, and there are approximately 600 million BQ chewers worldwide. Although chewing BQ has been linked to the patho-genesis of oral cancer, leukoplakia, and oral submucous fibrosis. The quest
Externí odkaz:
https://doaj.org/article/94e2d4b8bf104a0d8e002350d3020309
Publikováno v:
Journal of the Formosan Medical Association, Vol 107, Iss 7, Pp 513-518 (2008)
Background/Purpose: Accumulating literature has documented that there exists a distinct difference in nitro blue tetrazolium reduction capacity by the polymorphonuclear neutrophils (PMNs) from patients with different types of leukemia. The underlying
Externí odkaz:
https://doaj.org/article/e74d832a709b466a8f6aa09d72352424
Autor:
Ruo-Chiau Wang, Chien-Yu Huang, Tai-Long Pan, Wei-Yu Chen, Chun-Te Ho, Tsan-Zon Liu, Yu-Jia Chang
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139232 (2015)
To search for reliable biomarkers and drug targets for management of hepatocellular carcinoma (HCC), we performed a global proteomic analysis of a pair of HCC cell lines with distinct differentiation statuses using 2-DE coupled with MALDI-TOF MS. In
Externí odkaz:
https://doaj.org/article/68e405a6d57b42eda273fa11a40b1a36
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136340 (2015)
Here, we present evidence of a novel microtubule-disrupting agent, N-deacetyl-N-(chromone-2-carbonyl)-thiocolchicine (TCD), exhibiting potent antitumor activity (with IC50 values in the nanomolar range) against hepatocellular carcinoma cell lines. Ce
Externí odkaz:
https://doaj.org/article/71830de5f4fc4986ba783aa6b4502820
Autor:
Hung-Chih Hsu, Jeng-Fong Chiou, Yu-Huei Wang, Chia-Hui Chen, Shin-Yi Mau, Chun-Te Ho, Pey-Jium Chang, Tsan-Zon Liu, Ching-Hsein Chen
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e77931 (2013)
It has been postulated that folic acid (folate) deficiency (FD) may be a risk factor for the pathogenesis of a variety of oxidative stress-triggered chronic degenerative diseases including diabetes, however, the direct evidence to lend support to thi
Externí odkaz:
https://doaj.org/article/cd5bbcd2128d4dca8edb854c9dfeb5fd
Autor:
Jeng Fong Chiou, Chu Yee Wu, Tsan Zon Liu, Sheng Ming Chen, Shun Liang Chen, Shung Sheng Tsou, Jan Show Chu
Publikováno v:
Journal of Food and Drug Analysis. 16
A novel spectrophotometric method for rapid quantification of acetaminophen in serum that is particularly suited for emergency usage is described. Free unconjugated acetaminophen is separated from other endogenous interferents by extracting the drug
Publikováno v:
Life Sciences. 198:25-31
Aims This study uncovered that the genetically endowed intracellular glutathione contents (iGSH) regulated by the catalytic subunit of γ‑glutamylcysteine synthetase heavy chain (γ‑GCSh) as a prime target for overcoming both the inherited and st
Autor:
Jinn‑Rung Kuo, Kun Goung Lai, Hung Sheng Shang, Chun‑Te Ho, Tsan Zon Liu, Jeng Fong Chiou, Yin Ju Chen
Publikováno v:
Oncology Letters
Cisplatin is commonly recognized as a DNA-damaging drug; however, its versatile antitumor effects have been demonstrated to extend beyond this narrow functional attribute. The present study determined how cisplatin regulates alternative pathways and