Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Tsan-Ju Chen"'
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 6, Pp 553-560 (2024)
Abstract Working memory (WM) is a cognitive function important for guiding the on‐going or upcoming behavior. A memory‐related protein Arc (activity‐regulated cytoskeleton‐associated protein) is implicated in long‐term memory consolidation.
Externí odkaz:
https://doaj.org/article/4cff6ff0af56404c83afd515a32c50a0
Autor:
Lin Kang, Ai-Lun Yang, Chao-Han Lai, Tsan-Ju Chen, Sung-Yen Lin, Yan-Hsiung Wang, Chau-Zen Wang, Edward M. Conway, Hua-Lin Wu, Mei-Ling Ho, Je-Ken Chang, Chung-Hwan Chen, Tsung-Lin Cheng
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9522
Osteoarthritis (OA) is a prevalent form of arthritis that affects over 32.5 million adults worldwide, causing significant cartilage damage and disability. Unfortunately, there are currently no effective treatments for OA, highlighting the need for no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb645635079e41681c804f624e888932
https://doi.org/10.3390/ijms24119522
https://doi.org/10.3390/ijms24119522
Publikováno v:
Journal of Cellular Physiology. 231:2428-2438
Cholinergic dysfunction in the brain is closely related to cognitive impairment including memory loss. In addition to the degeneration of basal forebrain cholinergic neurons, deficits in the cholinergic receptor signaling may also play an important r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64c8a7d4162335e3358f4d9afe31c903
https://doi.org/10.1002/jcp.25347
https://doi.org/10.1002/jcp.25347
Publikováno v:
Journal of cellular physiology. 235(2)
Chronic high-fat-diet (HFD) consumption can lead to the development of brain insulin resistance, which then exerts deleterious effects on learning and memory. Activity-regulated cytoskeleton-associated protein (Arc) is a memory-related protein, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b4750aaa4c7642800706c8936656603
https://pubmed.ncbi.nlm.nih.gov/31264208
https://pubmed.ncbi.nlm.nih.gov/31264208
Publikováno v:
Hormones and Behavior. 66:674-684
Both the detrimental effects of early life adversity and the beneficial effects of exercise on the hypothalamic-pituitary-adrenal (HPA) axis have been reported. Early life exposure to di-(2-ethylhexyl)-phthalate (DEHP) may impair the development of e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e40eade0685ddf551cc072381a7524b
https://doi.org/10.1016/j.yhbeh.2014.09.010
https://doi.org/10.1016/j.yhbeh.2014.09.010
Publikováno v:
Cellular and Molecular Life Sciences. 71:4069-4080
Learning and memory depend on long-term synaptic plasticity including long-term potentiation (LTP) and depression (LTD). Activity-regulated cytoskeleton-associated protein (Arc) plays versatile roles in synaptic plasticity mainly through inducing F-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfe1abb7cf4e889b795415c30000f666
https://doi.org/10.1007/s00018-014-1620-5
https://doi.org/10.1007/s00018-014-1620-5
Autor:
Jwu-Lai Yeh, Tsung Lin Cheng, Jong-Hau Hsu, Shu-Fen Liou, Tsan-Ju Chen, Chaw-Chi Chiu, Huai-Min Chen
Publikováno v:
The American Journal of Chinese Medicine. 42:785-797
Myocardial dysfunction, a common complication after sepsis, significantly contributes to the death of patients with septic shock. In the search for potentially effective drugs to decrease mortality from sepsis, we investigated the cardioprotective ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ce16b3b61a07b25a58a515927c5976
https://doi.org/10.1142/s0192415x14500505
https://doi.org/10.1142/s0192415x14500505
Publikováno v:
Toxicology Letters. 206:245-251
Di-(2-ethylhexyl) phthalate (DEHP) is widely used as a plasticizer in plastics. Its reproductive toxicity and teratogenic effects are well known. DEHP can cause liver damage and peroxisome proliferation, as well as carcinogenesis. Animal study has sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b6a29e7edbc6b867e4a9ecbc2f49db1
https://doi.org/10.1016/j.toxlet.2011.08.002
https://doi.org/10.1016/j.toxlet.2011.08.002
Publikováno v:
Toxicological Sciences. 116:264-272
Aluminum (Al) is a neurotoxicant and is implicated in several neurodegenerative diseases, including Alzheimer's disease (AD). In AD brains, one of the pathological hallmarks is the extracellular deposition of senile plaques, which are mainly composed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edb9c0071f6ddf6eb45ce2e3f86868e
https://doi.org/10.1093/toxsci/kfq114
https://doi.org/10.1093/toxsci/kfq114
Publikováno v:
Journal of Neuroscience Research. 87:2297-2307
The deposition of amyloid-beta (Abeta) contributes to the pathogenesis of Alzheimer's disease. Even at low levels, Abeta may interfere with various signaling cascades critical for the synaptic plasticity that underlies learning and memory. Brain-deri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed87cec14476235eb708d97ea7fb67d5
https://doi.org/10.1002/jnr.22057
https://doi.org/10.1002/jnr.22057