Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Tsafi Pe'ery"'
Autor:
Deepti Saxena, Michael Spino, Fernando Tricta, John Connelly, Bernadette M Cracchiolo, Axel-Rainer Hanauske, Darlene D'Alliessi Gandolfi, Michael B Mathews, Jonathan Karn, Bart Holland, Myung Hee Park, Tsafi Pe'ery, Paul E Palumbo, Hartmut M Hanauske-Abel
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154842 (2016)
UNLABELLED:Antiretrovirals suppress HIV-1 production yet spare the sites of HIV-1 production, the HIV-1 DNA-harboring cells that evade immune detection and enable viral resistance on-drug and viral rebound off-drug. Therapeutic ablation of pathogenic
Externí odkaz:
https://doaj.org/article/e17e5bea35ab4969b437207695534e81
Autor:
Hartmut M Hanauske-Abel, Deepti Saxena, Paul E Palumbo, Axel-Rainer Hanauske, Augusto D Luchessi, Tavane D Cambiaghi, Mainul Hoque, Michael Spino, Darlene D'Alliessi Gandolfi, Debra S Heller, Sukhwinder Singh, Myung Hee Park, Bernadette M Cracchiolo, Fernando Tricta, John Connelly, Anthony M Popowicz, Richard A Cone, Bart Holland, Tsafi Pe'ery, Michael B Mathews
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74414 (2013)
HIV-1 blocks apoptosis, programmed cell death, an innate defense of cells against viral invasion. However, apoptosis can be selectively reactivated in HIV-infected cells by chemical agents that interfere with HIV-1 gene expression. We studied two glo
Externí odkaz:
https://doaj.org/article/6c8d6c50e71847d2ba0749f5c2b0cea3
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1010 (2007)
The positive transcription elongation factor P-TEFb is a pivotal regulator of gene expression in higher cells. Originally identified in Drosophila, attention was drawn to human P-TEFb by the discovery of its role as an essential cofactor for HIV-1 tr
Externí odkaz:
https://doaj.org/article/b952716dcd044b2dbd3cdde8c284c721
Autor:
Michael B. Mathews, Tsafi Pe'ery, Hartmut M. Hanauske-Abel, Bernadette Cracchiolo, Hong Li, Debra S. Heller, Mohit R. Jain, Mainul Hoque, Elisabeth Mémin
PDF - 109K, Fig. S5. EF-P signals in target protein sequences.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::815db7588830f07f58d175dcb6aa1027
https://doi.org/10.1158/0008-5472.22401069
https://doi.org/10.1158/0008-5472.22401069
Autor:
Michael B. Mathews, Tsafi Pe'ery, Hartmut M. Hanauske-Abel, Bernadette Cracchiolo, Hong Li, Debra S. Heller, Mohit R. Jain, Mainul Hoque, Elisabeth Mémin
PDF - 468K, Fig. S1. Inhibition of DOHH by ciclopirox and deferiprone. Fig. S2. Cell cycle analysis. Fig. S3. Effects of CPX and DEF on cell size and morphology. Fig. S4. Effect of CPX and DEF on HeLa cell proteins analyzed by 2D gel electrophoresis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568d2a828f099f003ca853db6c68c93d
https://doi.org/10.1158/0008-5472.22401066
https://doi.org/10.1158/0008-5472.22401066
Autor:
Michael B. Mathews, Tsafi Pe'ery, Hartmut M. Hanauske-Abel, Bernadette Cracchiolo, Hong Li, Debra S. Heller, Mohit R. Jain, Mainul Hoque, Elisabeth Mémin
PDF - 74K, Table S1. Identification of drug-dependent spots.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8326ca1e124dd5366f87fb7307e8d663
https://doi.org/10.1158/0008-5472.22401063
https://doi.org/10.1158/0008-5472.22401063
Autor:
Hartmut M. Hanauske-Abel, Tsafi Pe'ery, Hong Li, Elisabeth Mémin, Bernadette Cracchiolo, Debra S. Heller, Mohit Jain, Michael B. Mathews, Mainul Hoque
Publikováno v:
Cancer Research. 74:552-562
Cancer etiology is influenced by alterations in protein synthesis that are not fully understood. In this study, we took a novel approach to investigate the role of the eukaryotic translation initiation factor eIF5A in human cervical cancers, where it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbba65be4df88ecb7a1bca10c4a913f0
https://doi.org/10.1158/0008-5472.can-13-0474
https://doi.org/10.1158/0008-5472.can-13-0474
Publikováno v:
Oncogene
The heterodimeric nuclear factor (NF) 90/NF45 complex (NF90/NF45) binds nucleic acids and is a multifunctional regulator of gene expression. Here we report that depletion of NF90/NF45 restores the expression of the p53 and p21 proteins in cervical ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c732123212b45a40fb14904870a3f3a
https://doi.org/10.1038/onc.2012.533
https://doi.org/10.1038/onc.2012.533
Autor:
Tsafi Pe'ery, Michael B. Mathews, Mainul Hoque, Raghavendra A. Shamanna, Anita Lewis-Antes, Edouard I. Azzam, David Lagunoff
Publikováno v:
Molecular and Cellular Biology. 31:4832-4843
Nuclear factor 90 (NF90), an RNA-binding protein implicated in the regulation of gene expression, exists as a heterodimeric complex with NF45. We previously reported that depletion of the NF90/NF45 complex results in a multinucleated phenotype. Time-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef926ad68344b546fd6970b86ef7206
https://doi.org/10.1128/mcb.05849-11
https://doi.org/10.1128/mcb.05849-11
The 3′UTR of HIC mRNA improves the production of recombinant proteins in Chinese hamster ovary cells
Autor:
Sheng-Hao Chao, Jaron Liu, Jialing Lee, Sebastian C. Y. Ku, Tsafi Pe'ery, Michael B. Mathews, Tara M. Young
Publikováno v:
Journal of Biotechnology. 139:152-155
Positive transcription elongation factor b (P-TEFb) is an important transcriptional regulator which controls 70–80% of RNA polymerase II transcription. It has been reported that the human I-mfa (inhibitor of MyoD family a) domain-containing protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5885d3757498dd543c2c82aaa9f32b05
https://doi.org/10.1016/j.jbiotec.2008.10.008
https://doi.org/10.1016/j.jbiotec.2008.10.008