Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of l-tryptophan

Autor: Jannette Carey, Claes von Wachenfeldt, Catherine L. Lawson, Leila Lo Leggio, Janina Sprenger

Publikováno v: Acta Crystallographica. Section F, Structural Biology Communications
Sprenger, J, Lawson, C L, Von Wachenfeldt, C, Lo Leggio, L & Carey, J 2021, ' Crystal structures of Val58Ile tryptophan repressor in a domain-swapped array in the presence and absence of L-tryptophan ', Acta Crystallographica Section F: Structural Biology Communications, vol. 77, no. 7, pp. 215-225 . https://doi.org/10.1107/S2053230X21006142
Acta crystallographica / F 77(7), 215-225 (2021). doi:10.1107/S2053230X21006142
'Acta Crystallographica F ', vol: 77, pages: 215-225 (2021)

Acta crystallographica / F 77(7), 215 - 225 (2021). doi:10.1107/S2053230X21006142
The crystal structures of domain-swapped tryptophan repressor (TrpR) variant Val58Ile before and after soaking with the physiological ligand L-tryptophan (L-Trp) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fdd02e404cf01d9ff7f9267298f98f0
http://europepmc.org/articles/PMC8248821

Tryptophan Operon Diversity Reveals Evolutionary Trends among Geographically Disparate Chlamydia trachomatis Ocular and Urogenital Strains Affecting Tryptophan Repressor and Synthase Function

Autor: Naraporn Somboonna, Gracie Richards, Sankhya Bommana, Deborah Dean, Maryam Tarazkar

Publikováno v: mBio, vol 12, iss 3
mBio
mBio, Vol 12, Iss 3 (2021)

The obligate intracellular pathogen Chlamydia trachomatis (Ct) is the leading cause of bacterial sexually transmitted infections and blindness globally. To date, Ct urogenital strains are considered tryptophan prototrophs, utilizing indole for trypto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c363c321023a980a03b50cfe9fab9030
https://doi.org/10.1128/mbio.00605-21

Design of a biosensor for direct visualisation of auxin

Autor: O. Herud-Sikimic, Andre C. Stiel, Sooruban Shanmugaratnam, Ortega-Perez M, Birte Höcker, Gerd Jürgens

In plants, one of the most important regulative small molecules is indole-3-acetic acid (IAA) known as auxin. Its dynamic redistribution plays an essential role in virtually every aspect of plant life, ranging from cell shape and division to organoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efb52febb38b385bfa5c8a8f7c385c92
https://doi.org/10.1101/2020.01.19.911735

Trp-ing upon new repressors

Autor: Andreas K. Brödel, Mark Isalan

Publikováno v: Nature Chemical Biology. 14:328-329

Bioengineers have used directed evolution to generate a new family of synthetic transcription factors based on the tryptophan repressor. The evolved repressor family enables researchers to build new gene circuits for biomedical applications.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f84f4858353c88829a4aea11c3d7a04
https://doi.org/10.1038/s41589-018-0012-9

Proteomic Analysis to Identify the Role of LuxS/AI-2 Mediated Protein Expression in Escherichia coli O157:H7

Autor: Martha L. Cepeda, William K. Russell, Brad J. Williams, Suresh D. Pillai, Palmy R. Jesudhasan, Kamlesh A. Soni, M.E. Hume, Arul Jayaraman

Publikováno v: Foodborne Pathogens and Disease. 4:463-471

Microorganisms employ autoinducer molecules to modulate various bacterial processes including virulence expression, biofilm development, and bioluminescence. The universal autoinducer molecule AI-2 is hypothesized to mediate cell signaling in Escheri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d705309826bdb20437a46cc247e9c4
https://doi.org/10.1089/fpd.2007.0034