Infliximab Therapeutic monitoring by tryptic peptide LC-MS/MS method improvements lead to improved accuracy with decreased imprecision and turnaround time

Autor: Paula M. Ladwig, Ann L. Rivard, Alex Barbeln, Anthony Maus, David L. Murray, Melissa R. Snyder, Maria A.V. Willrich

Publikováno v: Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 32, Iss , Pp 24-30 (2024)

Introduction: Therapeutic drug monitoring of infliximab has become the standard of care for inflammatory bowel disease in the setting of loss of response to therapy, and occasionally in proactive therapy personalization. Measurement of infliximab by

Externí odkaz: https://doaj.org/article/eca8d07ac2a540d78f474e928cb0c67d

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Isobaric Labeling Proteomics Allows a High-Throughput Investigation of Protein Corona Orientation

Autor: Nara Liessi, Valentina Castagnola, Fabio Benfenati, Andrea Armirotti, Mattia Bramini, Luca Maragliano

Publikováno v: Analytical Chemistry
Digibug. Repositorio Institucional de la Universidad de Granada
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Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)

The formation of the biomolecular corona represents a crucial factor in controlling the biological interactions and trafficking of nanomaterials. In this context, the availability of key epitopes exposed on the surface of the corona, and able to enga

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8809e4f4e1fe808d205985d31002d1bb
https://doi.org/10.1021/acs.analchem.0c03134

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Picoflow Liquid Chromatography–Mass Spectrometry for Ultrasensitive Bottom-Up Proteomics Using 2-μm-i.d. Open Tubular Columns

Autor: Sarah M. Williams, Shaorong Liu, Richard D. Smith, Ryan T. Kelly, Zhitao Zhao, Piliang Xiang, Ronald J. Moore, Ying Zhu, Yu Yang

Publikováno v: Anal Chem

In many areas of application, key objectives of chemical separation and analysis are to minimize the sample quantity while maximizing the chemical information obtained. Increasing measurement sensitivity is especially critical for proteomics research

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8eb306c6320efe0d07294b7cca36888
https://doi.org/10.1021/acs.analchem.9b05639